Project name: 3hmx:L
Status: done
submitted: 2019-03-20 20:10:17, status changed: 2019-03-20 20:24:43
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCRASQGISSWLAWYQQKPEKAPKSLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYNIYPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7093
-
Maximal score value
-
1.5217
-
Average score
-
-0.8048
-
Total score value
-
-172.2223
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.7915 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-1.8192 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-0.7361 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.6070 |
|
| 8 |
P |
L |
-0.3770 |
|
| 9 |
S |
L |
-0.7306 |
|
| 10 |
S |
L |
-0.5293 |
|
| 11 |
L |
L |
-0.2010 |
|
| 12 |
S |
L |
-0.7054 |
|
| 13 |
A |
L |
0.0000 |
|
| 14 |
S |
L |
-0.7092 |
|
| 15 |
V |
L |
0.2380 |
|
| 16 |
G |
L |
-0.8102 |
|
| 17 |
D |
L |
-1.6504 |
|
| 18 |
R |
L |
-2.2925 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.5590 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.6360 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-1.9610 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-1.9187 |
|
| 27 |
Q |
L |
-2.1174 |
|
| 28 |
G |
L |
-1.3690 |
|
| 29 |
I |
L |
0.0000 |
|
| 30 |
S |
L |
-0.6662 |
|
| 31 |
S |
L |
-0.2072 |
|
| 32 |
W |
L |
0.6985 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
A |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.0910 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.6596 |
|
| 39 |
K |
L |
-2.2168 |
|
| 40 |
P |
L |
-2.2430 |
|
| 41 |
E |
L |
-2.9428 |
|
| 42 |
K |
L |
-3.0760 |
|
| 43 |
A |
L |
-1.8084 |
|
| 44 |
P |
L |
-1.6319 |
|
| 45 |
K |
L |
-1.7922 |
|
| 46 |
S |
L |
-0.8106 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
0.7312 |
|
| 50 |
A |
L |
0.4287 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-0.1416 |
|
| 53 |
S |
L |
0.0753 |
|
| 54 |
L |
L |
0.1172 |
|
| 55 |
Q |
L |
-0.5735 |
|
| 56 |
S |
L |
-0.6427 |
|
| 57 |
G |
L |
-0.6537 |
|
| 58 |
V |
L |
-0.4891 |
|
| 59 |
P |
L |
-0.3772 |
|
| 60 |
S |
L |
-0.4106 |
|
| 61 |
R |
L |
-0.8448 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.1925 |
|
| 64 |
G |
L |
-0.1837 |
|
| 65 |
S |
L |
-0.7543 |
|
| 66 |
G |
L |
-1.1370 |
|
| 67 |
S |
L |
-1.0083 |
|
| 68 |
G |
L |
-1.1645 |
|
| 69 |
T |
L |
-1.7084 |
|
| 70 |
D |
L |
-2.4708 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7317 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6312 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.4152 |
|
| 77 |
S |
L |
-1.2341 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-1.0804 |
|
| 80 |
P |
L |
-1.0648 |
|
| 81 |
E |
L |
-1.9413 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
-0.6119 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
-0.7927 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.0897 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.5328 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
Y |
L |
1.1673 |
|
| 92 |
N |
L |
0.6227 |
|
| 93 |
I |
L |
1.2973 |
|
| 94 |
Y |
L |
1.5217 |
|
| 95 |
P |
L |
0.8514 |
|
| 96 |
Y |
L |
1.0269 |
|
| 97 |
T |
L |
0.4394 |
|
| 98 |
F |
L |
0.9685 |
|
| 99 |
G |
L |
-0.2863 |
|
| 100 |
Q |
L |
-1.0333 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.2670 |
|
| 104 |
L |
L |
0.0000 |
|
| 105 |
E |
L |
-0.9992 |
|
| 106 |
I |
L |
-0.8051 |
|
| 107 |
K |
L |
-1.5657 |
|
| 108 |
R |
L |
-2.2146 |
|
| 109 |
T |
L |
-0.5267 |
|
| 110 |
V |
L |
0.4455 |
|
| 111 |
A |
L |
0.0121 |
|
| 112 |
A |
L |
-0.2289 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.2262 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.1371 |
|
| 117 |
I |
L |
1.0972 |
|
| 118 |
F |
L |
1.3482 |
|
| 119 |
P |
L |
-0.2458 |
|
| 120 |
P |
L |
-0.7303 |
|
| 121 |
S |
L |
-1.9246 |
|
| 122 |
D |
L |
-3.2575 |
|
| 123 |
E |
L |
-3.4210 |
|
| 124 |
Q |
L |
-2.5427 |
|
| 125 |
L |
L |
-2.5409 |
|
| 126 |
K |
L |
-3.0130 |
|
| 127 |
S |
L |
-1.9602 |
|
| 128 |
G |
L |
-1.3094 |
|
| 129 |
T |
L |
-1.0077 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0089 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.5431 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.5736 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.7722 |
|
| 138 |
N |
L |
-1.7173 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.5169 |
|
| 142 |
R |
L |
-2.1778 |
|
| 143 |
E |
L |
-2.7922 |
|
| 144 |
A |
L |
-2.1175 |
|
| 145 |
K |
L |
-2.3698 |
|
| 146 |
V |
L |
-1.1913 |
|
| 147 |
Q |
L |
-0.7755 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.6798 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.8746 |
|
| 152 |
N |
L |
-1.4401 |
|
| 153 |
A |
L |
-0.3362 |
|
| 154 |
L |
L |
0.6129 |
|
| 155 |
Q |
L |
-0.2277 |
|
| 156 |
S |
L |
-0.5048 |
|
| 157 |
G |
L |
-1.0114 |
|
| 158 |
N |
L |
-0.9886 |
|
| 159 |
S |
L |
-1.5514 |
|
| 160 |
Q |
L |
-2.3334 |
|
| 161 |
E |
L |
-2.2536 |
|
| 162 |
S |
L |
-0.8141 |
|
| 163 |
V |
L |
0.0493 |
|
| 164 |
T |
L |
-0.8246 |
|
| 165 |
E |
L |
-2.0816 |
|
| 166 |
Q |
L |
-2.1276 |
|
| 167 |
D |
L |
-2.6922 |
|
| 168 |
S |
L |
-2.2234 |
|
| 169 |
K |
L |
-2.9531 |
|
| 170 |
D |
L |
-3.3034 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.8347 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.3180 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.7185 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.4554 |
|
| 181 |
L |
L |
-0.7115 |
|
| 182 |
S |
L |
-1.1844 |
|
| 183 |
K |
L |
-2.3341 |
|
| 184 |
A |
L |
-2.1059 |
|
| 185 |
D |
L |
-2.8778 |
|
| 186 |
Y |
L |
-2.6634 |
|
| 187 |
E |
L |
-3.6417 |
|
| 188 |
K |
L |
-3.7093 |
|
| 189 |
H |
L |
-3.3297 |
|
| 190 |
K |
L |
-3.2906 |
|
| 191 |
V |
L |
-1.8429 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.7630 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.1470 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.6572 |
|
| 200 |
G |
L |
-0.5772 |
|
| 201 |
L |
L |
-0.3422 |
|
| 202 |
S |
L |
-0.4485 |
|
| 203 |
S |
L |
-0.4175 |
|
| 204 |
P |
L |
-0.5248 |
|
| 205 |
V |
L |
0.1328 |
|
| 206 |
T |
L |
-0.3098 |
|
| 207 |
K |
L |
-0.3513 |
|
| 208 |
S |
L |
-0.3947 |
|
| 209 |
F |
L |
-1.3110 |
|
| 210 |
N |
L |
-2.8528 |
|
| 211 |
R |
L |
-3.2304 |
|
| 212 |
G |
L |
-2.3105 |
|
| 213 |
E |
L |
-2.2016 |
|
| 214 |
C |
L |
-0.4518 |
|