Project name: 6azl:A
Status: done
submitted: 2019-03-20 20:42:22, status changed: 2019-03-20 20:53:51
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7385
-
Maximal score value
-
1.8882
-
Average score
-
-0.8518
-
Total score value
-
-180.5869
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.4035 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.7467 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.3218 |
|
| 6 |
Q |
A |
0.0269 |
|
| 7 |
S |
A |
0.0622 |
|
| 8 |
P |
A |
0.8334 |
|
| 9 |
V |
A |
1.8882 |
|
| 10 |
I |
A |
1.3240 |
|
| 11 |
L |
A |
0.5384 |
|
| 12 |
S |
A |
-0.4570 |
|
| 13 |
V |
A |
0.0000 |
|
| 14 |
S |
A |
-1.9336 |
|
| 15 |
P |
A |
-2.2111 |
|
| 16 |
G |
A |
-2.3473 |
|
| 17 |
E |
A |
-3.1411 |
|
| 18 |
R |
A |
-3.5103 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.7714 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-0.8596 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.6248 |
|
| 25 |
A |
A |
-1.3931 |
|
| 26 |
S |
A |
-1.0548 |
|
| 27 |
Q |
A |
-1.6441 |
|
| 28 |
S |
A |
-1.5907 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.1047 |
|
| 31 |
T |
A |
-0.8590 |
|
| 32 |
N |
A |
-1.1053 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.1950 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.6093 |
|
| 39 |
R |
A |
-2.4309 |
|
| 40 |
T |
A |
-1.9592 |
|
| 41 |
N |
A |
-2.0278 |
|
| 42 |
G |
A |
-1.5985 |
|
| 43 |
S |
A |
-1.1262 |
|
| 44 |
P |
A |
-1.0463 |
|
| 45 |
R |
A |
-0.8146 |
|
| 46 |
L |
A |
-0.1314 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.9276 |
|
| 50 |
Y |
A |
-0.3858 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.2375 |
|
| 53 |
E |
A |
-1.9810 |
|
| 54 |
S |
A |
-1.1416 |
|
| 55 |
I |
A |
-0.4951 |
|
| 56 |
S |
A |
-0.2505 |
|
| 57 |
G |
A |
-0.4146 |
|
| 58 |
I |
A |
-0.1897 |
|
| 59 |
P |
A |
-0.3183 |
|
| 60 |
S |
A |
-0.6327 |
|
| 61 |
R |
A |
-1.3186 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-1.0052 |
|
| 64 |
G |
A |
0.0000 |
|
| 65 |
S |
A |
-0.8483 |
|
| 66 |
G |
A |
-1.2038 |
|
| 67 |
S |
A |
-1.1914 |
|
| 68 |
G |
A |
-1.4343 |
|
| 69 |
T |
A |
-2.0680 |
|
| 70 |
D |
A |
-2.8699 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.9376 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-0.9914 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.8869 |
|
| 77 |
S |
A |
-2.6315 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-3.0538 |
|
| 80 |
S |
A |
-2.7687 |
|
| 81 |
E |
A |
-3.0412 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
-1.8870 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-0.7829 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.1376 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.2112 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.4018 |
|
| 92 |
N |
A |
-1.8262 |
|
| 93 |
N |
A |
-1.3413 |
|
| 94 |
W |
A |
0.0331 |
|
| 95 |
P |
A |
-0.1592 |
|
| 96 |
T |
A |
-0.4991 |
|
| 97 |
T |
A |
0.2608 |
|
| 98 |
F |
A |
1.3440 |
|
| 99 |
G |
A |
0.5903 |
|
| 100 |
A |
A |
0.5956 |
|
| 101 |
G |
A |
0.3384 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-0.1054 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-1.0755 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.7900 |
|
| 108 |
R |
A |
-1.2795 |
|
| 109 |
T |
A |
-0.2337 |
|
| 110 |
V |
A |
0.1039 |
|
| 111 |
A |
A |
-0.1926 |
|
| 112 |
A |
A |
-0.2099 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
0.0005 |
|
| 115 |
V |
A |
0.4489 |
|
| 116 |
F |
A |
1.3584 |
|
| 117 |
I |
A |
1.2988 |
|
| 118 |
F |
A |
1.5008 |
|
| 119 |
P |
A |
-0.0512 |
|
| 120 |
P |
A |
-0.7101 |
|
| 121 |
S |
A |
-1.8107 |
|
| 122 |
D |
A |
-3.2543 |
|
| 123 |
E |
A |
-3.4255 |
|
| 124 |
Q |
A |
-2.4895 |
|
| 125 |
L |
A |
-2.5857 |
|
| 126 |
K |
A |
-3.0048 |
|
| 127 |
S |
A |
-1.9068 |
|
| 128 |
G |
A |
-1.5142 |
|
| 129 |
T |
A |
-1.1211 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0628 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.7240 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.5722 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.5220 |
|
| 138 |
N |
A |
-1.2051 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
-1.2700 |
|
| 141 |
P |
A |
-1.7731 |
|
| 142 |
R |
A |
-2.9222 |
|
| 143 |
E |
A |
-3.0747 |
|
| 144 |
A |
A |
-1.9445 |
|
| 145 |
K |
A |
-1.3910 |
|
| 146 |
V |
A |
-0.7456 |
|
| 147 |
Q |
A |
-0.6269 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.7317 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.9321 |
|
| 152 |
N |
A |
-1.3602 |
|
| 153 |
A |
A |
-0.3391 |
|
| 154 |
L |
A |
0.4861 |
|
| 155 |
Q |
A |
-0.2627 |
|
| 156 |
S |
A |
-0.4876 |
|
| 157 |
G |
A |
-1.0556 |
|
| 158 |
N |
A |
-1.0470 |
|
| 159 |
S |
A |
-1.4396 |
|
| 160 |
Q |
A |
-2.2629 |
|
| 161 |
E |
A |
-2.2245 |
|
| 162 |
S |
A |
-1.2847 |
|
| 163 |
V |
A |
-0.7796 |
|
| 164 |
T |
A |
-1.2311 |
|
| 165 |
E |
A |
-2.4661 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.3740 |
|
| 168 |
S |
A |
-2.7873 |
|
| 169 |
K |
A |
-2.9651 |
|
| 170 |
D |
A |
-2.1703 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-0.9708 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.4432 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.5705 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.3644 |
|
| 181 |
L |
A |
-0.6413 |
|
| 182 |
S |
A |
-1.0246 |
|
| 183 |
K |
A |
-2.0814 |
|
| 184 |
A |
A |
-1.9221 |
|
| 185 |
D |
A |
-2.5980 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.7382 |
|
| 188 |
K |
A |
-3.7385 |
|
| 189 |
H |
A |
-3.1853 |
|
| 190 |
K |
A |
-3.2085 |
|
| 191 |
V |
A |
-1.6247 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-0.8028 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-0.9184 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.5943 |
|
| 200 |
G |
A |
-0.4647 |
|
| 201 |
L |
A |
-0.2030 |
|
| 202 |
S |
A |
-0.4165 |
|
| 203 |
S |
A |
-0.3734 |
|
| 204 |
P |
A |
-0.3744 |
|
| 205 |
V |
A |
0.1367 |
|
| 206 |
T |
A |
-0.2837 |
|
| 207 |
K |
A |
-0.2641 |
|
| 208 |
S |
A |
-0.4237 |
|
| 209 |
F |
A |
-0.7955 |
|
| 210 |
N |
A |
-2.1849 |
|
| 211 |
R |
A |
-2.5789 |
|
| 212 |
G |
A |
-1.5893 |
|