Project name: 3J9T chain B

Chain sequence(s)	B: NTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFY
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.4879
• Maximal score value: 1.9516
• Average score: -0.7191
• Total score value: -328.6382

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
29	N	B	-2.0831
30	T	B	-1.5100
31	V	B	0.0000
32	S	B	-0.5770
33	G	B	0.0957
34	V	B	0.2552
35	N	B	-0.7641
36	G	B	-0.7726
37	P	B	-0.6412
38	L	B	0.0000
39	V	B	0.0000
40	I	B	-0.2376
41	L	B	0.0000
42	E	B	-2.6442
43	K	B	-1.9036
44	V	B	-0.9386
45	K	B	-1.9525
46	F	B	0.7018
47	P	B	0.0000
48	R	B	-1.1732
49	Y	B	0.1197
50	N	B	-0.5112
51	E	B	0.0000
52	I	B	0.0000
53	V	B	0.0000
54	N	B	-0.1812
55	L	B	0.0000
56	T	B	-0.7295
57	L	B	0.0000
58	P	B	-1.7695
59	D	B	-2.1355
60	G	B	-1.0326
61	T	B	-0.1478
62	V	B	0.8860
63	R	B	-0.1991
64	Q	B	-0.7473
65	G	B	0.0000
66	Q	B	-0.1604
67	V	B	0.0000
68	L	B	0.2742
69	E	B	-0.8748
70	I	B	-1.1639
71	R	B	-2.8317
72	G	B	-2.4320
73	D	B	-2.6934
74	R	B	-2.7981
75	A	B	0.0000
76	I	B	-0.4946
77	V	B	0.0000
78	Q	B	0.0000
79	V	B	0.0000
80	F	B	-1.1065
81	E	B	-2.0155
82	G	B	-1.5893
83	T	B	-0.8541
84	S	B	-0.8380
85	G	B	-0.6457
86	I	B	0.0000
87	D	B	-0.8858
88	V	B	0.0023
89	K	B	-2.1597
90	K	B	-2.6920
91	T	B	0.0000
92	T	B	-1.5098
93	V	B	-0.8816
94	E	B	-1.1980
95	F	B	0.5309
96	T	B	-0.4658
97	G	B	-1.3708
98	E	B	-2.1306
99	S	B	-1.7353
100	L	B	-1.0713
101	R	B	-1.6031
102	I	B	0.0000
103	P	B	-0.3784
104	V	B	0.0000
105	S	B	0.0000
106	E	B	-2.7805
107	D	B	-2.6479
108	M	B	0.0000
109	L	B	-1.2872
110	G	B	-1.3750
111	R	B	-1.0625
112	I	B	-0.6505
113	F	B	0.0000
114	D	B	-0.6957
115	G	B	0.0000
116	S	B	-0.7377
117	G	B	0.0000
118	R	B	-2.2000
119	P	B	-1.4723
120	I	B	-0.2540
121	D	B	-1.6261
122	N	B	-2.0546
123	G	B	-1.8074
124	P	B	-1.5843
125	K	B	-1.9338
126	V	B	-0.8903
127	F	B	-0.6415
128	A	B	-1.1956
129	E	B	-2.4144
130	D	B	-1.5441
131	Y	B	-0.2807
132	L	B	-0.2400
133	D	B	-0.8169
134	I	B	0.0000
135	N	B	-1.5775
136	G	B	-1.0052
137	S	B	-0.5512
138	P	B	0.2708
139	I	B	1.4637
140	N	B	-0.5624
141	P	B	-0.7442
142	Y	B	-0.7476
143	A	B	-0.9182
144	R	B	-1.1575
145	I	B	0.4984
146	Y	B	1.1491
147	P	B	-0.0590
148	E	B	-1.3710
149	E	B	-1.7700
150	M	B	0.0000
151	I	B	0.0000
152	S	B	0.0000
153	T	B	0.0000
154	G	B	0.0000
155	V	B	0.0000
156	S	B	0.0000
157	A	B	0.0000
158	I	B	0.0000
159	D	B	0.0000
160	T	B	0.0000
161	M	B	0.0000
162	N	B	0.0000
163	S	B	0.0000
164	I	B	0.0000
165	A	B	0.0000
166	R	B	0.0000
167	G	B	0.0000
168	Q	B	0.0000
169	K	B	-0.3193
170	I	B	0.0000
171	P	B	0.0000
172	I	B	0.0000
173	F	B	0.0000
174	S	B	0.0000
175	A	B	0.0000
176	S	B	-1.1586
177	G	B	-1.6070
178	L	B	0.0000
179	P	B	-0.7852
180	H	B	-0.8247
181	N	B	-0.9623
182	E	B	-1.4860
183	I	B	0.0000
184	A	B	0.0000
185	A	B	0.0000
186	Q	B	0.0000
187	I	B	0.0000
188	C	B	0.0000
189	R	B	0.0000
190	Q	B	0.0000
191	A	B	0.0000
192	G	B	0.0000
193	L	B	-0.2867
194	V	B	0.0000
195	R	B	-1.4430
196	P	B	-0.9684
197	T	B	-0.4446
198	K	B	0.0000
199	D	B	-2.1754
200	V	B	-0.1045
201	H	B	-1.3956
202	D	B	-2.7499
203	G	B	-2.2927
204	H	B	0.0000
205	E	B	-3.2383
206	E	B	-2.8076
207	N	B	-2.3441
208	F	B	0.0000
209	S	B	-0.7436
210	I	B	0.0000
211	V	B	0.0000
212	F	B	0.0000
213	A	B	0.0000
214	A	B	0.0000
215	M	B	0.0000
216	G	B	-0.7171
217	V	B	0.0000
218	N	B	-1.7124
219	L	B	-1.0592
220	E	B	-2.2783
221	T	B	-1.8922
222	A	B	0.0000
223	R	B	-2.6494
224	F	B	-2.0089
225	F	B	0.0000
226	K	B	-2.1967
227	Q	B	-2.8782
228	D	B	0.0000
229	F	B	0.0000
230	E	B	-3.4879
231	E	B	-2.8983
232	N	B	-1.6142
233	G	B	-2.0952
234	S	B	0.0000
235	L	B	-2.0125
236	E	B	-2.2830
237	R	B	-1.5196
238	T	B	0.0000
239	S	B	0.0000
240	L	B	0.0000
241	F	B	0.0000
242	L	B	0.0000
243	N	B	0.0000
244	L	B	-0.6370
245	A	B	-1.0785
246	N	B	-1.9304
247	D	B	-1.9159
248	P	B	-1.2533
249	T	B	-1.0399
250	I	B	0.0000
251	E	B	0.0000
252	R	B	-0.4459
253	I	B	0.0000
254	I	B	-0.1629
255	T	B	0.0000
256	P	B	0.0000
257	R	B	-0.5494
258	L	B	0.0000
259	A	B	0.0000
260	L	B	0.0000
261	T	B	0.0000
262	T	B	0.0000
263	A	B	0.0000
264	E	B	0.0000
265	Y	B	-0.2980
266	L	B	0.0000
267	A	B	0.0000
268	Y	B	-1.0620
269	Q	B	-1.3982
270	T	B	-1.3516
271	E	B	-1.8594
272	R	B	-1.8358
273	H	B	0.0000
274	V	B	0.0000
275	L	B	0.0000
276	T	B	0.0000
277	I	B	0.0000
278	L	B	0.0000
279	T	B	0.0000
280	D	B	-0.2835
281	M	B	0.0000
282	S	B	0.0000
283	S	B	-0.5286
284	Y	B	0.0000
285	A	B	0.0000
286	D	B	-1.6144
287	A	B	0.0000
288	L	B	0.0000
289	R	B	-2.4463
290	E	B	-2.6278
291	V	B	0.0000
292	S	B	-1.3688
293	A	B	-1.0056
294	A	B	-1.0276
295	R	B	-1.7306
296	E	B	-2.3775
297	E	B	-1.7248
298	V	B	0.2122
299	P	B	-0.7445
300	G	B	-1.5438
301	R	B	-3.0240
302	R	B	-3.0294
303	G	B	-2.2304
304	Y	B	-1.8732
305	P	B	0.0000
306	G	B	-0.6836
307	Y	B	0.1491
308	M	B	0.0000
309	Y	B	0.7128
310	T	B	0.2295
311	D	B	-0.0400
312	L	B	0.0000
313	S	B	-0.2044
314	T	B	-0.6845
315	I	B	0.0000
316	Y	B	0.0000
317	E	B	-1.4966
318	R	B	0.0000
319	A	B	0.0000
320	G	B	-0.3724
321	R	B	0.0000
322	V	B	0.0000
323	E	B	-2.5983
324	G	B	-2.0217
325	R	B	-1.8078
326	N	B	-2.4677
327	G	B	0.0000
328	S	B	0.0000
329	I	B	0.0000
330	T	B	0.0000
331	Q	B	0.0000
332	I	B	0.0000
333	P	B	0.0000
334	I	B	0.0000
335	L	B	0.0000
336	T	B	0.0000
337	M	B	0.0000
338	P	B	-1.5665
339	N	B	-2.3250
340	D	B	-2.6497
341	D	B	-1.4801
342	I	B	0.1887
343	T	B	-0.0033
344	H	B	0.0000
345	P	B	0.0000
346	I	B	0.0000
347	P	B	0.0000
348	D	B	0.2459
349	L	B	0.7059
350	T	B	0.0000
351	G	B	0.5766
352	Y	B	1.3584
353	I	B	1.0587
354	T	B	0.0000
355	E	B	-0.6792
356	G	B	-0.4447
357	Q	B	-0.2250
358	I	B	0.0000
359	F	B	0.3831
360	V	B	0.0000
361	D	B	-1.6159
362	R	B	-3.0305
363	Q	B	-2.9564
364	L	B	0.0000
365	H	B	-2.1732
366	N	B	-3.0566
367	K	B	-3.0840
368	G	B	-2.0276
369	I	B	0.0000
370	Y	B	0.3331
371	P	B	0.0000
372	P	B	0.0000
373	I	B	0.0000
374	N	B	-0.3699
375	V	B	0.0000
376	L	B	0.4130
377	P	B	0.3121
378	S	B	0.0000
379	L	B	0.2577
380	S	B	0.0000
381	R	B	-1.9675
382	L	B	-1.1773
383	M	B	-1.2543
384	K	B	-2.0919
385	S	B	-1.3902
386	A	B	0.0000
387	I	B	-1.5863
388	G	B	-2.2083
389	E	B	-2.9284
390	G	B	-2.0704
391	M	B	0.0000
392	T	B	0.0000
393	R	B	-1.8010
394	K	B	-2.3827
395	D	B	0.0000
396	H	B	0.0000
397	G	B	0.0000
398	D	B	-1.5425
399	V	B	0.0000
400	S	B	-0.9075
401	N	B	-1.5595
402	Q	B	0.0000
403	L	B	0.0000
404	Y	B	0.2242
405	A	B	0.1700
406	K	B	0.0000
407	Y	B	0.0000
408	A	B	0.2065
409	I	B	0.3998
410	G	B	0.0000
411	K	B	-1.2408
412	D	B	-1.5902
413	A	B	0.0000
414	A	B	-0.7756
415	A	B	0.0382
416	M	B	0.4088
417	K	B	-0.4091
418	A	B	0.7784
419	V	B	1.9516
420	V	B	0.8193
421	G	B	-0.6467
422	E	B	-2.4940
423	E	B	-2.6293
424	A	B	-0.8337
425	L	B	-0.6365
426	S	B	-0.2678
427	I	B	0.7880
428	E	B	-1.0099
429	D	B	-1.2163
430	K	B	-1.3098
431	L	B	-0.5983
432	S	B	0.0000
433	L	B	-1.6497
434	E	B	-2.3826
435	F	B	0.0000
436	L	B	0.0000
437	E	B	-3.2023
438	K	B	-2.6410
439	F	B	0.0000
440	E	B	0.0000
441	K	B	-2.5700
442	T	B	-1.4230
443	F	B	0.0000
444	I	B	0.0000
445	T	B	-0.3967
446	Q	B	0.0000
447	G	B	-0.0594
448	A	B	0.1841
449	Y	B	0.3563
450	E	B	-0.7791
451	D	B	-1.3479
452	R	B	-1.0340
453	T	B	0.0000
454	V	B	0.0000
455	F	B	-0.8093
456	E	B	-1.8822
457	S	B	0.0000
458	L	B	0.0000
459	D	B	-2.3000
460	Q	B	-1.6491
461	A	B	0.0000
462	W	B	0.0000
463	S	B	-1.1668
464	L	B	0.0000
465	L	B	0.0000
466	R	B	-1.5537
467	I	B	-0.5289
468	Y	B	0.0000
469	P	B	-1.4635
470	K	B	-2.6844
471	E	B	-2.5806
472	M	B	-1.6692
473	L	B	0.0000
474	N	B	-2.4255
475	R	B	-1.7206
476	I	B	0.0000
477	S	B	-1.4585
478	P	B	-2.2085
479	K	B	-2.6741
480	I	B	-2.0006
481	L	B	0.0000
482	D	B	-3.1165
483	E	B	-2.6903
484	F	B	-1.4282
485	Y	B	-0.9334