Project name: mab8

Chain sequence(s)	H: QVQLYQSGAEVKKPGSSVKVSCKASGGTFSTYGISWVRQAPGQGLEWMGGIIPIFDTGNSAQSFQGRVTITADESTSTAYMELSSLRSEQTAVYYCAASNKLYDLNPSLTAYYDMQVWGQGTMVTVS; L: SVLTQPPSVSAAPGQKVTISCSGSSSQVGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAWVFGGGTQLTVLRT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0132
• Maximal score value: 1.1371
• Average score: -0.6084
• Total score value: -144.7913

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-0.7694
2	V	H	0.4613
3	Q	H	-0.3066
4	L	H	0.0000
5	Y	H	0.0340
6	Q	H	0.0000
7	S	H	-0.7073
8	G	H	-0.6676
9	A	H	-0.0814
10	E	H	-0.3681
11	V	H	0.7064
12	K	H	-1.1177
13	K	H	-2.1730
14	P	H	-2.0843
15	G	H	-1.5854
16	S	H	-1.2722
17	S	H	-1.5586
18	V	H	0.0000
19	K	H	-1.9222
20	V	H	0.0000
21	S	H	-0.6576
22	C	H	0.0000
23	K	H	-1.5569
24	A	H	0.0000
25	S	H	-0.6945
26	G	H	-0.9476
27	G	H	-1.1384
28	T	H	-1.0626
29	F	H	0.0000
30	S	H	-0.3777
31	T	H	0.4265
32	Y	H	0.1355
33	G	H	0.0000
34	I	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.6925
40	A	H	0.0000
41	P	H	-1.1030
42	G	H	-1.2840
43	Q	H	-1.8069
44	G	H	-1.0548
45	L	H	0.0000
46	E	H	-0.7200
47	W	H	-0.2348
48	M	H	0.0000
49	G	H	0.0000
50	G	H	-0.7374
51	I	H	0.0000
52	I	H	0.0000
52A	P	H	0.0000
53	I	H	0.5936
54	F	H	0.8532
55	D	H	-1.3661
56	T	H	-0.8516
57	G	H	-1.3786
58	N	H	-1.8696
59	S	H	-1.7313
60	A	H	-1.0642
61	Q	H	-1.7076
62	S	H	-1.4435
63	F	H	0.0000
64	Q	H	-2.6652
65	G	H	-2.1809
66	R	H	-2.7064
67	V	H	0.0000
68	T	H	-1.3081
69	I	H	-0.6229
70	T	H	-0.7419
71	A	H	-1.2396
72	D	H	-1.9843
73	E	H	-2.1757
74	S	H	-1.3088
75	T	H	-1.3490
76	S	H	0.0000
77	T	H	-1.2724
78	A	H	0.0000
79	Y	H	-0.5923
80	M	H	0.0000
81	E	H	-1.8057
82	L	H	0.0000
82A	S	H	-1.6139
82B	S	H	-1.4318
82C	L	H	0.0000
83	R	H	-3.0132
84	S	H	-2.3858
85	E	H	-2.5739
86	Q	H	0.0000
87	T	H	-0.7669
88	A	H	0.0000
89	V	H	0.3706
90	Y	H	0.0000
91	Y	H	0.0674
92	C	H	0.0000
93	A	H	0.0000
94	A	H	0.0000
95	S	H	0.0000
96	N	H	-0.8762
97	K	H	-0.0400
98	L	H	1.0692
99	Y	H	1.0792
100	D	H	-0.9680
100A	L	H	-0.4502
100B	N	H	-1.3169
100C	P	H	-0.9815
100D	S	H	-0.5216
100E	L	H	-0.0361
100F	T	H	-0.3262
100G	A	H	0.1714
100H	Y	H	0.3234
100I	Y	H	0.0534
100J	D	H	-0.0788
100K	M	H	0.0000
101	Q	H	-0.4332
102	V	H	-0.0933
103	W	H	0.0000
104	G	H	0.0000
105	Q	H	-1.0307
106	G	H	-0.3376
107	T	H	0.0000
108	M	H	0.3521
109	V	H	0.0000
110	T	H	-0.3192
111	V	H	0.0000
112	S	H	-1.1693
2	S	L	-0.3987
3	V	L	0.5829
4	L	L	0.0000
5	T	L	-0.1516
6	Q	L	0.0000
7	P	L	-0.5175
8	P	L	-0.7694
10	S	L	-0.7868
11	V	L	-0.2736
12	S	L	-0.4566
13	A	L	0.0000
14	A	L	-0.8916
15	P	L	-1.4218
16	G	L	-1.7237
17	Q	L	-2.2222
18	K	L	-2.4691
19	V	L	0.0000
20	T	L	-0.5101
21	I	L	0.0000
22	S	L	-0.3441
23	C	L	0.0000
24	S	L	-0.3317
25	G	L	-0.3217
26	S	L	-0.6620
27	S	L	-0.9749
28	S	L	-0.6053
29	Q	L	-0.3665
30	V	L	0.0000
30A	G	L	-1.2350
30B	N	L	-1.4102
31	N	L	0.0000
32	Y	L	0.1206
33	V	L	0.0000
34	S	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	0.0000
38	Q	L	-0.8761
39	L	L	-0.5744
40	P	L	-0.5706
41	G	L	-0.6423
42	T	L	-0.6290
43	A	L	-0.6509
44	P	L	-0.7985
45	K	L	-1.0466
46	L	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	-0.4762
50	D	L	-1.2804
51	N	L	-1.5139
52	N	L	-2.4431
53	K	L	-2.7058
54	R	L	-1.7615
55	P	L	-0.6904
56	S	L	-0.5543
57	G	L	-0.7506
58	I	L	-0.8922
59	P	L	-1.2740
60	D	L	-2.3248
61	R	L	-1.6440
62	F	L	0.0000
63	S	L	-1.3980
64	G	L	-1.3371
65	S	L	-1.3504
66	K	L	-1.0443
67	S	L	-0.8145
68	G	L	-1.0642
69	T	L	-0.9788
70	S	L	-0.7252
71	A	L	0.0000
72	T	L	-0.5912
73	L	L	0.0000
74	G	L	-0.6222
75	I	L	0.0000
76	T	L	-1.7997
77	G	L	-1.6948
78	L	L	0.0000
79	Q	L	-1.8883
80	T	L	-1.3821
81	G	L	-1.3372
82	D	L	0.0000
83	E	L	-2.3810
84	A	L	0.0000
85	D	L	-1.3374
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	G	L	0.0000
90	T	L	0.0000
91	W	L	0.3058
92	D	L	0.0000
93	S	L	-0.0142
94	S	L	0.3920
95	L	L	1.1371
95A	S	L	0.2193
95B	A	L	0.0000
96	W	L	0.0000
97	V	L	0.0000
98	F	L	0.0000
99	G	L	0.0000
100	G	L	-0.7758
101	G	L	-0.7947
102	T	L	0.0000
103	Q	L	-1.8064
104	L	L	0.0000
105	T	L	-0.7735
106	V	L	-0.7311
107	L	L	0.1720
108	R	L	-1.2871
109	T	L	-0.7328