Project name: mab7

Chain sequence(s)	H: QVQLVQSGAEAKKPGSSVKVSCKASGGTFSTYGISWVRQAPGQGLEWMGGIIPIFDTGNSARSFQGRVTITADESTSTAYMELSSLRSEQTAVYYCASSSRIYDLNPSLTAYYDMQVWGQGTMVTVS; L: SVLTQPPSVSAAPGQKVTISCSGSSSDIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLRTGDEADYYCGTWDSSLSAWVFGGGTKLTVLRT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8976
• Maximal score value: 1.9629
• Average score: -0.6144
• Total score value: -146.2156

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-0.6694
2	V	H	0.6931
3	Q	H	-0.5178
4	L	H	0.0000
5	V	H	-0.2300
6	Q	H	0.0000
7	S	H	-0.7808
8	G	H	-0.7025
9	A	H	-0.4668
10	E	H	-1.2420
11	A	H	-0.9821
12	K	H	-1.8571
13	K	H	-2.4738
14	P	H	-2.1975
15	G	H	-1.5774
16	S	H	-1.2626
17	S	H	-1.4213
18	V	H	0.0000
19	K	H	-2.0604
20	V	H	0.0000
21	S	H	-0.7450
22	C	H	0.0000
23	K	H	-1.6876
24	A	H	0.0000
25	S	H	-0.8086
26	G	H	-0.9367
27	G	H	-1.1651
28	T	H	-1.0893
29	F	H	0.0000
30	S	H	-0.1763
31	T	H	1.0112
32	Y	H	0.9695
33	G	H	0.0000
34	I	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.5750
40	A	H	0.0000
41	P	H	-1.0709
42	G	H	-1.2535
43	Q	H	-1.7677
44	G	H	0.0000
45	L	H	0.0000
46	E	H	-0.6575
47	W	H	0.0000
48	M	H	0.0000
49	G	H	0.0000
50	G	H	-0.5846
51	I	H	0.0000
52	I	H	0.0000
52A	P	H	0.0000
53	I	H	0.4029
54	F	H	0.5034
55	D	H	-1.5760
56	T	H	-0.8703
57	G	H	-1.1734
58	N	H	-1.4184
59	S	H	-1.4390
60	A	H	0.0000
61	R	H	-2.4356
62	S	H	-1.5335
63	F	H	0.0000
64	Q	H	-2.3309
65	G	H	-1.5881
66	R	H	-1.3525
67	V	H	-1.0529
68	T	H	-0.8841
69	I	H	-0.5196
70	T	H	-0.7854
71	A	H	-1.3285
72	D	H	-2.1494
73	E	H	-2.5707
74	S	H	-1.4966
75	T	H	-1.4670
76	S	H	0.0000
77	T	H	-1.3784
78	A	H	0.0000
79	Y	H	-0.6337
80	M	H	0.0000
81	E	H	-1.5813
82	L	H	0.0000
82A	S	H	-1.1893
82B	S	H	-1.1841
82C	L	H	0.0000
83	R	H	-2.8976
84	S	H	-2.3167
85	E	H	-2.5380
86	Q	H	0.0000
87	T	H	-0.9540
88	A	H	0.0000
89	V	H	0.2912
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	A	H	0.0000
94	S	H	0.0000
95	S	H	0.0000
96	S	H	0.5427
97	R	H	0.0000
98	I	H	1.9629
99	Y	H	1.4032
100	D	H	-0.8026
100A	L	H	-0.2369
100B	N	H	-1.2014
100C	P	H	-0.9627
100D	S	H	-0.4525
100E	L	H	0.2581
100F	T	H	-0.1024
100G	A	H	0.1472
100H	Y	H	0.4636
100I	Y	H	0.3849
100J	D	H	0.0000
100K	M	H	0.0000
101	Q	H	-0.3718
102	V	H	0.2112
103	W	H	-0.0737
104	G	H	0.0000
105	Q	H	-1.0493
106	G	H	-0.4468
107	T	H	0.0000
108	M	H	0.0444
109	V	H	0.0000
110	T	H	-0.9628
111	V	H	0.0000
112	S	H	-1.4723
2	S	L	-0.0487
3	V	L	1.0110
4	L	L	0.0000
5	T	L	-0.1234
6	Q	L	-0.5406
7	P	L	-0.6324
8	P	L	-0.9206
10	S	L	-1.0029
11	V	L	-0.3781
12	S	L	-0.5347
13	A	L	0.0000
14	A	L	-1.0453
15	P	L	-1.7415
16	G	L	-1.9730
17	Q	L	-2.3824
18	K	L	-2.4865
19	V	L	0.0000
20	T	L	-0.5032
21	I	L	0.0000
22	S	L	-0.3645
23	C	L	0.0000
24	S	L	-0.4001
25	G	L	-0.2918
26	S	L	-0.5630
27	S	L	-0.9493
28	S	L	-0.7391
29	D	L	0.0000
30	I	L	0.0000
30A	G	L	-1.2407
30B	N	L	-1.4122
31	N	L	0.0000
32	Y	L	0.0876
33	V	L	0.0000
34	S	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	0.0000
38	Q	L	-0.4377
39	L	L	0.3889
40	P	L	-0.1487
41	G	L	-0.2309
42	T	L	-0.2663
43	A	L	-0.4352
44	P	L	0.0000
45	K	L	-0.9571
46	L	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	-0.9339
50	D	L	-1.4160
51	N	L	-1.6296
52	N	L	-2.5431
53	K	L	-2.8840
54	R	L	-1.9404
55	P	L	-0.9329
56	S	L	-0.6120
57	G	L	-0.7405
58	I	L	-0.9082
59	P	L	-1.1845
60	D	L	-2.2452
61	R	L	-1.5883
62	F	L	0.0000
63	S	L	-1.4143
64	G	L	-1.3763
65	S	L	-1.2433
66	K	L	-1.0117
67	S	L	-0.8077
68	G	L	-1.0475
69	T	L	-0.9496
70	S	L	-0.6966
71	A	L	0.0000
72	T	L	-0.5808
73	L	L	0.0000
74	G	L	-0.5937
75	I	L	0.0000
76	T	L	-1.9099
77	G	L	-1.9604
78	L	L	0.0000
79	R	L	-2.7020
80	T	L	-1.8121
81	G	L	-1.4982
82	D	L	0.0000
83	E	L	-2.4121
84	A	L	0.0000
85	D	L	-1.2251
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	G	L	0.0000
90	T	L	0.0000
91	W	L	0.0000
92	D	L	0.0000
93	S	L	-0.5501
94	S	L	-0.2278
95	L	L	-0.2883
95A	S	L	-0.5593
95B	A	L	0.0000
96	W	L	0.0000
97	V	L	0.0000
98	F	L	0.0000
99	G	L	0.0000
100	G	L	-0.9026
101	G	L	-1.1529
102	T	L	0.0000
103	K	L	-2.3237
104	L	L	0.0000
105	T	L	-0.8809
106	V	L	-0.9318
107	L	L	0.1502
108	R	L	-1.2994
109	T	L	-0.7367