Project name: 5vr9:A

Chain sequence(s)	A: QVQLVQSGAEVKKPGASVKVSCKASGYTFTSHWMHWVRQAPGQGLEWIGEFNPSGRTNYNEKFKSKATMTVDTSTNTAYMELSSLRSEDTAVYYCASRDYDYDGRYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.3808
• Maximal score value: 2.5271
• Average score: -0.6446
• Total score value: -143.1048

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-1.3330
2	V	A	-0.7438
3	Q	A	-1.3065
4	L	A	0.0000
5	V	A	-0.2177
6	Q	A	0.0000
7	S	A	-0.8531
8	G	A	-1.2083
9	A	A	0.0000
10	E	A	-1.6927
11	V	A	-1.1188
12	K	A	-1.8033
13	K	A	-2.4363
14	P	A	-1.8718
15	G	A	-1.5340
16	A	A	-1.2230
17	S	A	-1.4514
18	V	A	0.0000
19	K	A	-2.1432
20	V	A	0.0000
21	S	A	-0.6244
22	C	A	0.0000
23	K	A	-1.1301
24	A	A	0.0000
25	S	A	-0.8152
26	G	A	-0.6991
27	Y	A	-0.0882
28	T	A	0.1108
29	F	A	0.0000
30	T	A	-0.2646
31	S	A	-0.1302
32	H	A	0.0000
33	W	A	-0.6817
34	M	A	0.0000
35	H	A	-0.3131
36	W	A	0.0000
37	V	A	0.0000
38	R	A	-0.3956
39	Q	A	-0.5865
40	A	A	-1.0348
41	P	A	-0.9644
42	G	A	-1.3199
43	Q	A	-1.6499
44	G	A	-0.8214
45	L	A	0.4801
46	E	A	-0.7373
47	W	A	-0.0953
48	I	A	0.0000
49	G	A	0.0000
50	E	A	-0.5031
51	F	A	-0.5582
52	N	A	-1.0104
53	P	A	-0.7712
54	S	A	-0.7815
56	G	A	-1.4013
57	R	A	-2.2372
58	T	A	-1.1839
59	N	A	-1.1632
60	Y	A	-1.2417
61	N	A	-2.0166
62	E	A	-3.3808
63	K	A	-3.3385
64	F	A	0.0000
65	K	A	-3.2208
66	S	A	-2.1801
67	K	A	-2.3114
68	A	A	0.0000
69	T	A	-1.0079
70	M	A	0.0000
71	T	A	-0.3777
72	V	A	-0.0120
73	D	A	-0.6611
74	T	A	-0.5251
75	S	A	-0.5121
76	T	A	-0.6873
77	N	A	-0.8824
78	T	A	0.0000
79	A	A	0.0000
80	Y	A	-0.4487
81	M	A	0.0000
82	E	A	-1.7124
83	L	A	0.0000
84	S	A	-1.3349
85	S	A	-1.2806
86	L	A	0.0000
87	R	A	-2.7004
88	S	A	-2.0981
89	E	A	-2.4015
90	D	A	0.0000
91	T	A	-0.9948
92	A	A	0.0000
93	V	A	0.2107
94	Y	A	0.0000
95	Y	A	0.1599
96	C	A	0.0000
97	A	A	0.0000
98	S	A	0.0000
99	R	A	-1.9521
100	D	A	-0.9173
101	Y	A	0.0920
102	D	A	-0.3323
103	Y	A	0.0408
104	D	A	-1.6116
105	G	A	-1.2049
106	R	A	-1.4671
107	Y	A	-0.1884
108	F	A	0.0000
109	D	A	-1.3164
110	Y	A	-0.8395
111	W	A	-0.2031
112	G	A	0.0000
113	Q	A	-0.9713
114	G	A	-0.3504
115	T	A	0.0000
116	L	A	-0.2243
117	V	A	0.0000
118	T	A	-0.9541
119	V	A	0.0000
120	S	A	-1.1727
121	S	A	-1.0546
122	A	A	-0.6343
123	S	A	-0.7001
124	T	A	-1.0015
125	K	A	-1.0478
126	G	A	-1.3639
127	P	A	-0.5343
128	S	A	-0.0646
129	V	A	0.0000
130	F	A	1.0221
131	P	A	-0.0028
132	L	A	0.4155
133	A	A	-0.9604
134	P	A	0.0000
135	S	A	-1.2851
136	S	A	-1.1626
137	K	A	-1.9017
138	S	A	-1.1570
139	T	A	-1.0795
140	S	A	-0.9317
141	G	A	-0.8666
142	G	A	-0.9085
143	T	A	-0.6378
144	A	A	0.0000
145	A	A	-0.1769
146	L	A	0.0000
147	G	A	0.0000
148	C	A	0.0000
149	L	A	0.7428
150	V	A	0.0000
151	K	A	-0.1138
152	D	A	-0.5187
153	Y	A	0.0000
154	F	A	-0.2311
155	P	A	0.0000
156	E	A	-0.4671
157	P	A	-0.7901
158	V	A	0.0000
159	T	A	-0.5850
160	V	A	-0.3956
161	S	A	-0.3481
162	W	A	0.0000
163	N	A	-0.8032
164	S	A	-0.6489
165	G	A	-0.5485
166	A	A	-0.2485
167	L	A	-0.0259
168	T	A	-0.2986
169	S	A	-0.3651
170	G	A	-0.4601
171	V	A	0.0146
172	H	A	-0.4455
173	T	A	0.1368
174	F	A	0.8288
175	P	A	0.6489
176	A	A	1.2627
177	V	A	2.5271
178	L	A	2.2106
179	Q	A	0.7578
180	S	A	0.0951
181	S	A	-0.2162
182	G	A	0.2275
183	L	A	0.4558
184	Y	A	0.9165
185	S	A	0.0000
186	L	A	0.0000
187	S	A	0.6488
188	S	A	0.0000
189	V	A	0.4513
190	V	A	0.0000
191	T	A	-0.2203
192	V	A	0.0000
193	P	A	-0.6263
194	S	A	-0.5804
195	S	A	-0.6088
196	S	A	-0.6542
197	L	A	-0.8369
198	G	A	-1.0012
199	T	A	-0.8335
200	Q	A	-1.5304
201	T	A	-1.2494
202	Y	A	0.0000
203	I	A	-1.2415
204	C	A	0.0000
205	N	A	0.0000
206	V	A	0.0000
207	N	A	-1.8542
208	H	A	0.0000
209	K	A	-2.9586
210	P	A	0.0000
211	S	A	-1.8980
212	N	A	-2.6661
213	T	A	-2.0847
214	K	A	-2.6533
215	V	A	-1.5039
216	D	A	-2.6212
217	K	A	-1.9718
218	K	A	-2.5453
219	V	A	0.0000
220	E	A	-2.9184
221	P	A	-1.9292
222	K	A	-2.3368
223	S	A	-1.3247