Project name: 5njd:M
Status: done
submitted: 2019-03-21 13:07:10, status changed: 2019-03-21 13:18:14
Settings
|
Chain sequence(s)
|
M: SVLTQPPSVSGAPGQRVTISCSGSRSNIGSNTVKWYQQLPGTAPKLLIYYNDQRPSGVPDRFSGSKSGTSASLAITGLQAEDEADYYCQSYDRYTHPALLFGTGTKVTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPT
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.1934
-
Maximal score value
-
1.9968
-
Average score
-
-0.6893
-
Total score value
-
-146.8265
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 2 |
S |
M |
0.9308 |
|
| 3 |
V |
M |
1.9968 |
|
| 4 |
L |
M |
0.0000 |
|
| 5 |
T |
M |
0.2612 |
|
| 6 |
Q |
M |
0.0000 |
|
| 7 |
P |
M |
-0.4015 |
|
| 8 |
P |
M |
-0.5985 |
|
| 9 |
S |
M |
-0.5917 |
|
| 10 |
V |
M |
-0.1802 |
|
| 11 |
S |
M |
-0.3020 |
|
| 12 |
G |
M |
-0.6533 |
|
| 13 |
A |
M |
-0.7918 |
|
| 14 |
P |
M |
-1.3494 |
|
| 15 |
G |
M |
-1.8002 |
|
| 16 |
Q |
M |
-2.4663 |
|
| 17 |
R |
M |
-2.5443 |
|
| 18 |
V |
M |
-1.0489 |
|
| 19 |
T |
M |
-0.4075 |
|
| 20 |
I |
M |
0.0000 |
|
| 21 |
S |
M |
-0.3864 |
|
| 22 |
C |
M |
0.0000 |
|
| 23 |
S |
M |
-0.2834 |
|
| 24 |
G |
M |
-0.6090 |
|
| 25 |
S |
M |
-1.3396 |
|
| 26 |
R |
M |
-2.4588 |
|
| 27 |
S |
M |
-1.4562 |
|
| 28 |
N |
M |
0.0000 |
|
| 29 |
I |
M |
0.0000 |
|
| 30 |
G |
M |
-1.7569 |
|
| 31 |
S |
M |
-1.2787 |
|
| 32 |
N |
M |
-0.7134 |
|
| 33 |
T |
M |
-0.0697 |
|
| 34 |
V |
M |
0.0000 |
|
| 35 |
K |
M |
-0.1091 |
|
| 36 |
W |
M |
0.0000 |
|
| 37 |
Y |
M |
-0.1720 |
|
| 38 |
Q |
M |
0.0000 |
|
| 39 |
Q |
M |
-0.8456 |
|
| 40 |
L |
M |
-0.6837 |
|
| 41 |
P |
M |
-0.6685 |
|
| 42 |
G |
M |
-0.6261 |
|
| 43 |
T |
M |
-0.5564 |
|
| 44 |
A |
M |
-0.4888 |
|
| 45 |
P |
M |
-0.8396 |
|
| 46 |
K |
M |
-1.1718 |
|
| 47 |
L |
M |
-0.2846 |
|
| 48 |
L |
M |
0.0000 |
|
| 49 |
I |
M |
0.0000 |
|
| 50 |
Y |
M |
-0.0249 |
|
| 51 |
Y |
M |
0.3270 |
|
| 52 |
N |
M |
-1.0383 |
|
| 53 |
D |
M |
-2.1437 |
|
| 54 |
Q |
M |
-1.7612 |
|
| 55 |
R |
M |
-1.6496 |
|
| 56 |
P |
M |
-0.9444 |
|
| 57 |
S |
M |
-0.6550 |
|
| 58 |
G |
M |
-0.8350 |
|
| 59 |
V |
M |
-1.0279 |
|
| 60 |
P |
M |
-1.3306 |
|
| 61 |
D |
M |
-2.3222 |
|
| 62 |
R |
M |
-1.6763 |
|
| 63 |
F |
M |
0.0000 |
|
| 64 |
S |
M |
-1.4160 |
|
| 65 |
G |
M |
0.0000 |
|
| 66 |
S |
M |
-1.1307 |
|
| 67 |
K |
M |
-1.1524 |
|
| 68 |
S |
M |
-0.8518 |
|
| 69 |
G |
M |
-1.1766 |
|
| 70 |
T |
M |
-1.1955 |
|
| 71 |
S |
M |
-0.9064 |
|
| 72 |
A |
M |
0.0000 |
|
| 73 |
S |
M |
-0.6305 |
|
| 74 |
L |
M |
0.0000 |
|
| 75 |
A |
M |
-0.5450 |
|
| 76 |
I |
M |
0.0000 |
|
| 77 |
T |
M |
-1.6557 |
|
| 78 |
G |
M |
-1.6644 |
|
| 79 |
L |
M |
0.0000 |
|
| 80 |
Q |
M |
-2.0906 |
|
| 81 |
A |
M |
-1.5927 |
|
| 82 |
E |
M |
-2.2979 |
|
| 83 |
D |
M |
0.0000 |
|
| 84 |
E |
M |
0.0000 |
|
| 85 |
A |
M |
0.0000 |
|
| 86 |
D |
M |
-0.7709 |
|
| 87 |
Y |
M |
0.0000 |
|
| 88 |
Y |
M |
-0.0285 |
|
| 89 |
C |
M |
0.0000 |
|
| 90 |
Q |
M |
0.0000 |
|
| 91 |
S |
M |
0.0000 |
|
| 92 |
Y |
M |
0.2857 |
|
| 93 |
D |
M |
-1.0988 |
|
| 94 |
R |
M |
-1.9101 |
|
| 95 |
Y |
M |
-0.0171 |
|
| 96 |
T |
M |
-0.2939 |
|
| 97 |
H |
M |
-1.0521 |
|
| 98 |
P |
M |
-0.4200 |
|
| 99 |
A |
M |
0.3279 |
|
| 100 |
L |
M |
1.6018 |
|
| 101 |
L |
M |
0.0000 |
|
| 102 |
F |
M |
1.6391 |
|
| 103 |
G |
M |
0.9077 |
|
| 104 |
T |
M |
0.3800 |
|
| 105 |
G |
M |
-0.2903 |
|
| 106 |
T |
M |
0.0000 |
|
| 107 |
K |
M |
-1.0044 |
|
| 108 |
V |
M |
0.0000 |
|
| 109 |
T |
M |
-0.0214 |
|
| 110 |
V |
M |
0.0000 |
|
| 111 |
L |
M |
0.6197 |
|
| 112 |
G |
M |
-0.4414 |
|
| 113 |
Q |
M |
-0.7152 |
|
| 114 |
P |
M |
-1.1660 |
|
| 115 |
K |
M |
-2.2484 |
|
| 116 |
A |
M |
-1.4018 |
|
| 117 |
A |
M |
-0.8279 |
|
| 118 |
P |
M |
-0.5343 |
|
| 119 |
S |
M |
-0.3637 |
|
| 120 |
V |
M |
0.0000 |
|
| 121 |
T |
M |
0.2946 |
|
| 122 |
L |
M |
0.9532 |
|
| 123 |
F |
M |
1.9570 |
|
| 124 |
P |
M |
0.8362 |
|
| 125 |
P |
M |
0.0000 |
|
| 126 |
S |
M |
-1.0148 |
|
| 127 |
S |
M |
-1.7042 |
|
| 128 |
E |
M |
-2.8575 |
|
| 129 |
E |
M |
-2.5237 |
|
| 130 |
L |
M |
-2.5046 |
|
| 131 |
Q |
M |
-2.6212 |
|
| 132 |
A |
M |
-2.1664 |
|
| 133 |
N |
M |
-2.9564 |
|
| 134 |
K |
M |
-3.1370 |
|
| 135 |
A |
M |
0.0000 |
|
| 136 |
T |
M |
-0.0697 |
|
| 137 |
L |
M |
0.0000 |
|
| 138 |
V |
M |
1.1903 |
|
| 139 |
C |
M |
0.0000 |
|
| 140 |
L |
M |
0.8576 |
|
| 141 |
I |
M |
0.0000 |
|
| 142 |
S |
M |
-0.7091 |
|
| 143 |
D |
M |
-1.4799 |
|
| 144 |
F |
M |
0.0000 |
|
| 145 |
Y |
M |
0.0000 |
|
| 146 |
P |
M |
-0.9460 |
|
| 147 |
G |
M |
-0.7263 |
|
| 148 |
A |
M |
-0.1093 |
|
| 149 |
V |
M |
0.0620 |
|
| 150 |
T |
M |
0.0979 |
|
| 151 |
V |
M |
0.1462 |
|
| 152 |
A |
M |
-0.3174 |
|
| 153 |
W |
M |
0.0000 |
|
| 154 |
K |
M |
-0.8968 |
|
| 155 |
A |
M |
-0.9585 |
|
| 156 |
D |
M |
-1.2626 |
|
| 157 |
S |
M |
-0.8484 |
|
| 158 |
S |
M |
-0.5494 |
|
| 159 |
P |
M |
-0.7674 |
|
| 160 |
V |
M |
-0.5728 |
|
| 161 |
K |
M |
-1.4856 |
|
| 162 |
A |
M |
-0.9127 |
|
| 163 |
G |
M |
-0.7044 |
|
| 164 |
V |
M |
-0.5228 |
|
| 165 |
E |
M |
-1.4120 |
|
| 166 |
T |
M |
-0.6260 |
|
| 167 |
T |
M |
-0.4921 |
|
| 168 |
T |
M |
-0.1699 |
|
| 169 |
P |
M |
-0.3175 |
|
| 170 |
S |
M |
-0.6510 |
|
| 171 |
K |
M |
-1.1602 |
|
| 172 |
Q |
M |
-1.3500 |
|
| 173 |
S |
M |
-1.2433 |
|
| 174 |
N |
M |
-1.6767 |
|
| 175 |
N |
M |
-1.5988 |
|
| 176 |
K |
M |
-1.5294 |
|
| 177 |
Y |
M |
-1.0444 |
|
| 178 |
A |
M |
-0.6112 |
|
| 179 |
A |
M |
-0.1589 |
|
| 180 |
S |
M |
0.0388 |
|
| 181 |
S |
M |
0.0000 |
|
| 182 |
Y |
M |
0.2460 |
|
| 183 |
L |
M |
0.0000 |
|
| 184 |
S |
M |
-0.5744 |
|
| 185 |
L |
M |
0.0000 |
|
| 186 |
T |
M |
-1.8171 |
|
| 187 |
P |
M |
-2.5616 |
|
| 188 |
E |
M |
-3.1345 |
|
| 189 |
Q |
M |
-2.3309 |
|
| 190 |
W |
M |
0.0000 |
|
| 191 |
K |
M |
-3.1934 |
|
| 192 |
S |
M |
-2.4840 |
|
| 193 |
H |
M |
-2.4936 |
|
| 194 |
R |
M |
-2.6820 |
|
| 195 |
S |
M |
-1.5166 |
|
| 196 |
Y |
M |
0.0000 |
|
| 197 |
S |
M |
0.0000 |
|
| 198 |
C |
M |
0.0000 |
|
| 199 |
Q |
M |
-0.8102 |
|
| 200 |
V |
M |
0.0000 |
|
| 201 |
T |
M |
-0.5973 |
|
| 202 |
H |
M |
0.0000 |
|
| 203 |
E |
M |
-2.3154 |
|
| 204 |
G |
M |
-1.3847 |
|
| 205 |
S |
M |
-0.9156 |
|
| 206 |
T |
M |
-0.6758 |
|
| 207 |
V |
M |
-0.6388 |
|
| 208 |
E |
M |
-1.5896 |
|
| 209 |
K |
M |
-1.1010 |
|
| 210 |
T |
M |
-0.4912 |
|
| 211 |
V |
M |
0.1353 |
|
| 212 |
A |
M |
-0.5714 |
|
| 213 |
P |
M |
-0.9544 |
|
| 214 |
T |
M |
-0.4641 |
|