Project name: 5m5e:D
Status: done
submitted: 2019-03-21 14:49:35, status changed: 2019-03-21 14:55:56
Settings
|
Chain sequence(s)
|
B: SQFTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPA
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.2284
-
Maximal score value
-
1.7536
-
Average score
-
-0.689
-
Total score value
-
-139.8723
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 6 |
S |
B |
-1.5493 |
|
| 7 |
Q |
B |
-1.4130 |
|
| 8 |
F |
B |
0.0311 |
|
| 9 |
T |
B |
0.0220 |
|
| 10 |
C |
B |
0.0000 |
|
| 11 |
F |
B |
-0.0281 |
|
| 12 |
Y |
B |
0.0000 |
|
| 13 |
N |
B |
-0.6884 |
|
| 14 |
S |
B |
0.0000 |
|
| 15 |
R |
B |
-1.2221 |
|
| 16 |
A |
B |
0.0000 |
|
| 17 |
N |
B |
-0.4644 |
|
| 18 |
I |
B |
0.0000 |
|
| 19 |
S |
B |
-0.3618 |
|
| 20 |
C |
B |
0.0000 |
|
| 21 |
V |
B |
0.7088 |
|
| 22 |
W |
B |
0.0000 |
|
| 23 |
S |
B |
-0.7356 |
|
| 24 |
Q |
B |
-1.2951 |
|
| 25 |
D |
B |
-2.1623 |
|
| 26 |
G |
B |
-1.1343 |
|
| 27 |
A |
B |
-0.3439 |
|
| 28 |
L |
B |
-0.0797 |
|
| 29 |
Q |
B |
-0.9622 |
|
| 30 |
D |
B |
-1.9487 |
|
| 31 |
T |
B |
-1.5447 |
|
| 32 |
S |
B |
-1.1197 |
|
| 33 |
C |
B |
0.0000 |
|
| 34 |
Q |
B |
-0.6399 |
|
| 35 |
V |
B |
0.0000 |
|
| 36 |
H |
B |
-0.1770 |
|
| 37 |
A |
B |
0.0000 |
|
| 38 |
W |
B |
-0.3485 |
|
| 39 |
P |
B |
0.0000 |
|
| 40 |
D |
B |
-1.9398 |
|
| 41 |
R |
B |
-2.3223 |
|
| 42 |
R |
B |
-2.6975 |
|
| 43 |
R |
B |
-2.7488 |
|
| 44 |
W |
B |
-1.7469 |
|
| 45 |
N |
B |
-1.6139 |
|
| 46 |
Q |
B |
-0.5077 |
|
| 47 |
T |
B |
-0.7597 |
|
| 48 |
C |
B |
-0.8320 |
|
| 49 |
E |
B |
-1.4410 |
|
| 50 |
L |
B |
0.0000 |
|
| 51 |
L |
B |
1.4797 |
|
| 52 |
P |
B |
1.1434 |
|
| 53 |
V |
B |
1.7536 |
|
| 54 |
S |
B |
0.1568 |
|
| 55 |
Q |
B |
-0.8912 |
|
| 56 |
A |
B |
-0.6709 |
|
| 57 |
S |
B |
0.1154 |
|
| 58 |
W |
B |
0.0000 |
|
| 59 |
A |
B |
0.5662 |
|
| 60 |
C |
B |
0.0000 |
|
| 61 |
N |
B |
-1.0843 |
|
| 62 |
L |
B |
0.0000 |
|
| 63 |
I |
B |
0.7583 |
|
| 64 |
L |
B |
0.0000 |
|
| 65 |
G |
B |
-0.3018 |
|
| 66 |
A |
B |
-0.6395 |
|
| 67 |
P |
B |
-1.1460 |
|
| 68 |
D |
B |
-2.2818 |
|
| 69 |
S |
B |
-1.4478 |
|
| 70 |
Q |
B |
-1.2445 |
|
| 71 |
K |
B |
-1.0092 |
|
| 72 |
L |
B |
0.0000 |
|
| 73 |
T |
B |
0.3885 |
|
| 74 |
T |
B |
0.6224 |
|
| 75 |
V |
B |
1.3812 |
|
| 76 |
D |
B |
0.0000 |
|
| 77 |
I |
B |
-0.4093 |
|
| 78 |
V |
B |
0.0000 |
|
| 79 |
T |
B |
-0.3872 |
|
| 80 |
L |
B |
0.0000 |
|
| 81 |
R |
B |
0.5108 |
|
| 82 |
V |
B |
0.0000 |
|
| 83 |
L |
B |
-0.4527 |
|
| 84 |
C |
B |
0.0000 |
|
| 85 |
R |
B |
-2.3764 |
|
| 86 |
E |
B |
-2.5926 |
|
| 87 |
G |
B |
-1.1670 |
|
| 88 |
V |
B |
-0.0373 |
|
| 89 |
R |
B |
-1.9034 |
|
| 90 |
W |
B |
-1.3445 |
|
| 91 |
R |
B |
-1.6628 |
|
| 92 |
V |
B |
0.6667 |
|
| 93 |
M |
B |
0.7721 |
|
| 94 |
A |
B |
0.9812 |
|
| 95 |
I |
B |
1.6971 |
|
| 96 |
Q |
B |
-0.2904 |
|
| 97 |
D |
B |
-1.6514 |
|
| 98 |
F |
B |
0.0000 |
|
| 99 |
K |
B |
-1.2445 |
|
| 100 |
P |
B |
0.0000 |
|
| 101 |
F |
B |
0.0000 |
|
| 102 |
E |
B |
-1.4211 |
|
| 103 |
N |
B |
-0.6388 |
|
| 104 |
L |
B |
0.0000 |
|
| 105 |
R |
B |
-0.7035 |
|
| 106 |
L |
B |
0.0000 |
|
| 107 |
M |
B |
0.2685 |
|
| 108 |
A |
B |
-0.1413 |
|
| 109 |
P |
B |
0.0000 |
|
| 110 |
I |
B |
-0.0790 |
|
| 111 |
S |
B |
-0.6216 |
|
| 112 |
L |
B |
-0.6074 |
|
| 113 |
Q |
B |
-0.7598 |
|
| 114 |
V |
B |
0.1593 |
|
| 115 |
V |
B |
0.9356 |
|
| 116 |
H |
B |
-0.7321 |
|
| 117 |
V |
B |
-1.4750 |
|
| 118 |
E |
B |
-3.0159 |
|
| 119 |
T |
B |
-2.5911 |
|
| 120 |
H |
B |
-2.6548 |
|
| 121 |
R |
B |
-3.2284 |
|
| 122 |
C |
B |
0.0000 |
|
| 123 |
N |
B |
-0.5223 |
|
| 124 |
I |
B |
0.0000 |
|
| 125 |
S |
B |
-0.4808 |
|
| 126 |
W |
B |
0.0000 |
|
| 127 |
E |
B |
-1.8260 |
|
| 128 |
I |
B |
-0.5422 |
|
| 129 |
S |
B |
-0.4691 |
|
| 130 |
Q |
B |
-1.0465 |
|
| 131 |
A |
B |
-0.7964 |
|
| 132 |
S |
B |
0.0000 |
|
| 133 |
H |
B |
-1.2953 |
|
| 134 |
Y |
B |
-0.3686 |
|
| 135 |
F |
B |
0.0000 |
|
| 136 |
E |
B |
-2.4660 |
|
| 137 |
R |
B |
-3.0825 |
|
| 138 |
H |
B |
-2.1646 |
|
| 139 |
L |
B |
0.0000 |
|
| 140 |
E |
B |
0.0000 |
|
| 141 |
F |
B |
0.0000 |
|
| 142 |
E |
B |
-0.2084 |
|
| 143 |
A |
B |
0.0000 |
|
| 144 |
R |
B |
-0.2846 |
|
| 145 |
T |
B |
-0.2662 |
|
| 146 |
L |
B |
-1.0080 |
|
| 147 |
S |
B |
-1.0927 |
|
| 148 |
P |
B |
-1.0905 |
|
| 149 |
G |
B |
-1.2742 |
|
| 150 |
H |
B |
-1.9833 |
|
| 151 |
T |
B |
-1.6946 |
|
| 152 |
W |
B |
-1.4556 |
|
| 153 |
E |
B |
-2.6681 |
|
| 154 |
E |
B |
-2.8692 |
|
| 155 |
A |
B |
-1.3716 |
|
| 156 |
P |
B |
-0.3938 |
|
| 157 |
L |
B |
0.6593 |
|
| 158 |
L |
B |
0.5433 |
|
| 159 |
T |
B |
-0.2916 |
|
| 160 |
L |
B |
0.0000 |
|
| 161 |
K |
B |
-2.2602 |
|
| 162 |
Q |
B |
-2.6745 |
|
| 163 |
K |
B |
-2.7683 |
|
| 164 |
Q |
B |
-1.9494 |
|
| 165 |
E |
B |
-1.8093 |
|
| 166 |
W |
B |
-0.2429 |
|
| 167 |
I |
B |
0.2157 |
|
| 168 |
C |
B |
-0.3298 |
|
| 169 |
L |
B |
0.0000 |
|
| 170 |
E |
B |
-2.6271 |
|
| 171 |
T |
B |
-1.5054 |
|
| 172 |
L |
B |
-1.4878 |
|
| 173 |
T |
B |
-1.6026 |
|
| 174 |
P |
B |
-2.0922 |
|
| 175 |
D |
B |
-2.6019 |
|
| 176 |
T |
B |
-1.9915 |
|
| 177 |
Q |
B |
-2.2494 |
|
| 178 |
Y |
B |
0.0000 |
|
| 179 |
E |
B |
-1.0213 |
|
| 180 |
F |
B |
0.0000 |
|
| 181 |
Q |
B |
0.0000 |
|
| 182 |
V |
B |
0.0000 |
|
| 183 |
R |
B |
-0.2620 |
|
| 184 |
V |
B |
0.0000 |
|
| 185 |
K |
B |
-0.3275 |
|
| 186 |
P |
B |
0.0000 |
|
| 187 |
L |
B |
0.2030 |
|
| 188 |
Q |
B |
-0.2359 |
|
| 189 |
G |
B |
-0.9597 |
|
| 190 |
E |
B |
-1.2513 |
|
| 191 |
F |
B |
0.4882 |
|
| 192 |
T |
B |
0.0391 |
|
| 193 |
T |
B |
-0.0105 |
|
| 194 |
W |
B |
-0.2292 |
|
| 195 |
S |
B |
0.0000 |
|
| 196 |
P |
B |
-0.2783 |
|
| 197 |
W |
B |
-0.1292 |
|
| 198 |
S |
B |
0.0000 |
|
| 199 |
Q |
B |
-1.0898 |
|
| 200 |
P |
B |
-0.5801 |
|
| 201 |
L |
B |
-0.4759 |
|
| 202 |
A |
B |
-0.7705 |
|
| 203 |
F |
B |
0.0000 |
|
| 204 |
R |
B |
-2.4987 |
|
| 205 |
T |
B |
0.0000 |
|
| 206 |
K |
B |
-3.1850 |
|
| 207 |
P |
B |
-1.9355 |
|
| 208 |
A |
B |
-0.9596 |
|