| Chain sequence(s) |
A: KPRVLVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQAFYNARRRQLQQPEIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCSQSGQVLDWTGDVTPEDKCPLRPHVVWFGEMPLGMDEIYMALSMADIFIAIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQEFAEKYYGPASQVVPEFVEKLLKGLK B: KGGARHR |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 40 | K | A | -2.3762 | |
| 41 | P | A | -1.7119 | |
| 42 | R | A | -2.3106 | |
| 43 | V | A | 0.0000 | |
| 44 | L | A | 0.0000 | |
| 45 | V | A | 0.0000 | |
| 46 | L | A | 0.0000 | |
| 47 | T | A | 0.0000 | |
| 48 | G | A | 0.0000 | |
| 49 | A | A | -0.3747 | |
| 50 | G | A | -0.7219 | |
| 51 | I | A | 0.0000 | |
| 52 | S | A | 0.0000 | |
| 53 | A | A | -1.1480 | |
| 54 | E | A | -1.8821 | |
| 55 | S | A | 0.0000 | |
| 56 | G | A | -1.6457 | |
| 57 | I | A | -1.2073 | |
| 58 | R | A | -2.1629 | |
| 59 | T | A | -1.4139 | |
| 60 | F | A | -1.0219 | |
| 61 | R | A | -2.3201 | |
| 62 | A | A | -1.8068 | |
| 63 | A | A | -1.5273 | |
| 64 | D | A | -2.4527 | |
| 65 | G | A | -2.1892 | |
| 66 | L | A | -2.0821 | |
| 67 | W | A | -2.2125 | |
| 68 | E | A | -2.2988 | |
| 69 | E | A | -2.6550 | |
| 70 | H | A | -2.3560 | |
| 71 | R | A | -3.1412 | |
| 72 | V | A | 0.0000 | |
| 73 | E | A | -2.7535 | |
| 74 | D | A | -2.5687 | |
| 75 | V | A | 0.0000 | |
| 76 | A | A | 0.0000 | |
| 77 | T | A | 0.0000 | |
| 78 | P | A | -1.9641 | |
| 79 | E | A | -3.4313 | |
| 80 | G | A | 0.0000 | |
| 81 | F | A | -2.7245 | |
| 82 | D | A | -3.7320 | |
| 83 | R | A | -3.7771 | |
| 84 | D | A | -2.9180 | |
| 85 | P | A | -2.4395 | |
| 86 | E | A | -2.3077 | |
| 87 | L | A | -0.7930 | |
| 88 | V | A | 0.0000 | |
| 89 | Q | A | -0.8905 | |
| 90 | A | A | -0.4892 | |
| 91 | F | A | 0.0000 | |
| 92 | Y | A | 0.0000 | |
| 93 | N | A | -1.0799 | |
| 94 | A | A | -1.2130 | |
| 95 | R | A | -1.4640 | |
| 96 | R | A | 0.0000 | |
| 97 | R | A | -2.9449 | |
| 98 | Q | A | -2.5623 | |
| 99 | L | A | 0.0000 | |
| 100 | Q | A | -2.5080 | |
| 101 | Q | A | -2.6768 | |
| 102 | P | A | -2.0313 | |
| 103 | E | A | -2.6678 | |
| 104 | I | A | 0.0000 | |
| 105 | Q | A | -2.3737 | |
| 106 | P | A | 0.0000 | |
| 107 | N | A | -0.6376 | |
| 108 | A | A | -0.4004 | |
| 109 | A | A | 0.0000 | |
| 110 | H | A | 0.0000 | |
| 111 | L | A | 0.2033 | |
| 112 | A | A | -0.9557 | |
| 113 | L | A | 0.0000 | |
| 114 | A | A | -1.4377 | |
| 115 | K | A | -2.4192 | |
| 116 | L | A | 0.0000 | |
| 117 | Q | A | -2.2107 | |
| 118 | D | A | -2.8320 | |
| 119 | A | A | -1.9776 | |
| 120 | L | A | 0.0000 | |
| 121 | G | A | -2.4849 | |
| 122 | D | A | -3.0393 | |
| 123 | R | A | -3.2249 | |
| 124 | F | A | 0.0000 | |
| 125 | L | A | -0.9502 | |
| 126 | L | A | 0.0000 | |
| 127 | V | A | 0.0000 | |
| 128 | T | A | 0.0000 | |
| 129 | Q | A | 0.0000 | |
| 130 | N | A | 0.0000 | |
| 131 | I | A | 0.0515 | |
| 132 | D | A | 0.0000 | |
| 133 | N | A | -1.0613 | |
| 134 | L | A | 0.0000 | |
| 135 | H | A | 0.0000 | |
| 136 | E | A | -1.8335 | |
| 137 | R | A | -2.1669 | |
| 138 | A | A | -1.2940 | |
| 139 | G | A | -1.5525 | |
| 140 | N | A | 0.0000 | |
| 141 | T | A | -1.2744 | |
| 142 | N | A | -1.2028 | |
| 143 | V | A | -0.4385 | |
| 144 | I | A | -0.1357 | |
| 145 | H | A | 0.0000 | |
| 146 | M | A | 0.0000 | |
| 147 | H | A | 0.2438 | |
| 148 | G | A | 0.0000 | |
| 149 | E | A | -0.4580 | |
| 150 | L | A | 0.0000 | |
| 151 | L | A | -0.9061 | |
| 152 | K | A | -0.9158 | |
| 153 | V | A | 0.0000 | |
| 154 | R | A | -1.1942 | |
| 155 | C | A | 0.0000 | |
| 156 | S | A | -1.3773 | |
| 157 | Q | A | -1.7987 | |
| 158 | S | A | -1.0899 | |
| 159 | G | A | -0.9509 | |
| 160 | Q | A | -0.8550 | |
| 161 | V | A | 0.2252 | |
| 162 | L | A | 0.1250 | |
| 163 | D | A | -1.3700 | |
| 164 | W | A | -0.8080 | |
| 165 | T | A | -1.1597 | |
| 166 | G | A | -1.3491 | |
| 167 | D | A | -1.2253 | |
| 168 | V | A | 0.0000 | |
| 169 | T | A | -1.6086 | |
| 170 | P | A | -1.9591 | |
| 171 | E | A | -2.5818 | |
| 172 | D | A | -2.1858 | |
| 173 | K | A | -2.3202 | |
| 174 | C | A | -0.5560 | |
| 182 | P | A | -1.5396 | |
| 183 | L | A | 0.0000 | |
| 184 | R | A | -0.8563 | |
| 185 | P | A | 0.0000 | |
| 186 | H | A | -0.4985 | |
| 187 | V | A | 0.0000 | |
| 188 | V | A | 0.3335 | |
| 189 | W | A | 0.0000 | |
| 190 | F | A | -0.7538 | |
| 191 | G | A | -0.8561 | |
| 192 | E | A | -0.1795 | |
| 193 | M | A | 0.3324 | |
| 194 | P | A | 0.0000 | |
| 195 | L | A | 0.1224 | |
| 196 | G | A | -0.8622 | |
| 197 | M | A | 0.0000 | |
| 198 | D | A | -2.6235 | |
| 199 | E | A | -2.0947 | |
| 200 | I | A | 0.0000 | |
| 201 | Y | A | -0.7917 | |
| 202 | M | A | 0.0584 | |
| 203 | A | A | 0.0000 | |
| 204 | L | A | 0.0000 | |
| 205 | S | A | 0.1955 | |
| 206 | M | A | 0.0943 | |
| 207 | A | A | 0.0000 | |
| 208 | D | A | -1.5566 | |
| 209 | I | A | -0.6240 | |
| 210 | F | A | 0.0000 | |
| 211 | I | A | 0.0000 | |
| 212 | A | A | 0.0000 | |
| 213 | I | A | 0.0000 | |
| 214 | G | A | 0.0000 | |
| 215 | T | A | 0.0000 | |
| 216 | S | A | -0.8568 | |
| 217 | G | A | -0.8521 | |
| 218 | H | A | -1.3694 | |
| 219 | V | A | 0.0000 | |
| 220 | Y | A | -0.7970 | |
| 221 | P | A | 0.0000 | |
| 222 | A | A | 0.0000 | |
| 223 | A | A | -0.7063 | |
| 224 | G | A | -0.4948 | |
| 225 | F | A | 0.0000 | |
| 226 | V | A | 0.0000 | |
| 227 | H | A | -1.3446 | |
| 228 | E | A | -0.6730 | |
| 229 | A | A | 0.0000 | |
| 230 | K | A | -1.3572 | |
| 231 | L | A | 0.2898 | |
| 232 | H | A | -0.7332 | |
| 233 | G | A | -0.9154 | |
| 234 | A | A | 0.0000 | |
| 235 | H | A | -0.9996 | |
| 236 | T | A | 0.0000 | |
| 237 | V | A | 0.0000 | |
| 238 | E | A | 0.0000 | |
| 239 | L | A | 0.0000 | |
| 240 | N | A | 0.0000 | |
| 241 | L | A | -0.0245 | |
| 242 | E | A | -1.4588 | |
| 243 | P | A | -1.1714 | |
| 244 | S | A | -0.9724 | |
| 245 | Q | A | -1.2417 | |
| 249 | E | A | -2.2144 | |
| 250 | F | A | 0.0000 | |
| 251 | A | A | -1.0354 | |
| 252 | E | A | -1.0653 | |
| 253 | K | A | -0.9948 | |
| 254 | Y | A | -0.1817 | |
| 255 | Y | A | 0.1019 | |
| 256 | G | A | -0.0355 | |
| 257 | P | A | -0.5355 | |
| 258 | A | A | 0.0000 | |
| 259 | S | A | -1.0391 | |
| 260 | Q | A | -1.5000 | |
| 261 | V | A | -0.8414 | |
| 262 | V | A | 0.0000 | |
| 263 | P | A | -1.9114 | |
| 264 | E | A | -2.9796 | |
| 265 | F | A | 0.0000 | |
| 266 | V | A | 0.0000 | |
| 267 | E | A | -3.7657 | |
| 268 | K | A | -3.4321 | |
| 269 | L | A | -2.0896 | |
| 270 | L | A | -2.4074 | |
| 271 | K | A | -3.2118 | |
| 272 | G | A | -2.1419 | |
| 273 | L | A | -1.5582 | |
| 274 | K | A | -2.4811 | |
| 12 | K | B | -2.0544 | |
| 13 | G | B | -1.1589 | |
| 14 | G | B | -0.8902 | |
| 15 | A | B | -0.5325 | |
| 17 | R | B | -1.8129 | |
| 18 | H | B | -1.9086 | |
| 19 | R | B | -2.3717 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine