Project name: 5itf:A
Status: done
submitted: 2019-03-20 20:32:30, status changed: 2019-03-20 20:43:47
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.8237
-
Maximal score value
-
1.7733
-
Average score
-
-0.8643
-
Total score value
-
-184.1048
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.4199 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.7702 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.3391 |
|
| 6 |
Q |
A |
-0.1212 |
|
| 7 |
S |
A |
-0.0256 |
|
| 8 |
P |
A |
0.7569 |
|
| 9 |
V |
A |
1.7733 |
|
| 10 |
I |
A |
1.2344 |
|
| 11 |
L |
A |
0.5211 |
|
| 12 |
S |
A |
-0.3195 |
|
| 13 |
V |
A |
-1.2096 |
|
| 14 |
S |
A |
-1.6912 |
|
| 15 |
P |
A |
-1.8582 |
|
| 16 |
G |
A |
-1.8959 |
|
| 17 |
E |
A |
-2.6043 |
|
| 18 |
R |
A |
-3.1764 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.8482 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-0.9346 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.6917 |
|
| 25 |
A |
A |
0.0000 |
|
| 26 |
S |
A |
-1.0912 |
|
| 27 |
Q |
A |
-1.5122 |
|
| 28 |
S |
A |
-1.6968 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.0666 |
|
| 31 |
T |
A |
-0.7349 |
|
| 32 |
N |
A |
-1.1065 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.0262 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.4937 |
|
| 39 |
R |
A |
-2.0479 |
|
| 40 |
T |
A |
-1.8425 |
|
| 41 |
N |
A |
-1.7559 |
|
| 42 |
G |
A |
-1.5046 |
|
| 43 |
S |
A |
-1.0724 |
|
| 44 |
P |
A |
-0.9838 |
|
| 45 |
R |
A |
-0.7346 |
|
| 46 |
L |
A |
-0.1003 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.7960 |
|
| 50 |
Y |
A |
-0.1108 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.1404 |
|
| 53 |
E |
A |
-1.9067 |
|
| 54 |
S |
A |
-1.1135 |
|
| 55 |
I |
A |
-0.5377 |
|
| 56 |
S |
A |
-0.2495 |
|
| 57 |
G |
A |
-0.4015 |
|
| 58 |
I |
A |
-0.1455 |
|
| 59 |
P |
A |
-0.2886 |
|
| 60 |
S |
A |
-0.6196 |
|
| 61 |
R |
A |
-1.2351 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-1.0074 |
|
| 64 |
G |
A |
-0.6857 |
|
| 65 |
S |
A |
-0.7929 |
|
| 66 |
G |
A |
-1.0818 |
|
| 67 |
S |
A |
-1.1379 |
|
| 68 |
G |
A |
-1.4497 |
|
| 69 |
T |
A |
-2.1117 |
|
| 70 |
D |
A |
-2.9133 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.9896 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-1.0191 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.7048 |
|
| 77 |
S |
A |
-2.2781 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-2.5362 |
|
| 80 |
S |
A |
-2.2657 |
|
| 81 |
E |
A |
-2.2368 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
-1.6385 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-1.0334 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.1221 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.1439 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.7201 |
|
| 92 |
N |
A |
-2.1510 |
|
| 93 |
N |
A |
-1.8540 |
|
| 94 |
W |
A |
-0.2833 |
|
| 95 |
P |
A |
-0.3395 |
|
| 96 |
T |
A |
-0.6935 |
|
| 97 |
T |
A |
0.2017 |
|
| 98 |
F |
A |
1.4600 |
|
| 99 |
G |
A |
0.6711 |
|
| 100 |
A |
A |
0.5435 |
|
| 101 |
G |
A |
0.2167 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-0.7216 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-1.0278 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.6419 |
|
| 108 |
R |
A |
-1.1837 |
|
| 109 |
T |
A |
-0.0737 |
|
| 110 |
V |
A |
0.5198 |
|
| 111 |
A |
A |
0.1363 |
|
| 112 |
A |
A |
-0.1582 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.1793 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.0231 |
|
| 117 |
I |
A |
1.0482 |
|
| 118 |
F |
A |
1.2783 |
|
| 119 |
P |
A |
-0.1094 |
|
| 120 |
P |
A |
-0.7655 |
|
| 121 |
S |
A |
-1.8068 |
|
| 122 |
D |
A |
-3.1759 |
|
| 123 |
E |
A |
-3.3766 |
|
| 124 |
Q |
A |
-2.4194 |
|
| 125 |
L |
A |
-2.5113 |
|
| 126 |
K |
A |
-2.9481 |
|
| 127 |
S |
A |
-1.8705 |
|
| 128 |
G |
A |
-1.3696 |
|
| 129 |
T |
A |
-1.1939 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0237 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.6640 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.4137 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.6302 |
|
| 138 |
N |
A |
-1.2971 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
0.0000 |
|
| 141 |
P |
A |
-1.7898 |
|
| 142 |
R |
A |
-3.1358 |
|
| 143 |
E |
A |
-3.2829 |
|
| 144 |
A |
A |
-2.4246 |
|
| 145 |
K |
A |
-2.6177 |
|
| 146 |
V |
A |
0.0000 |
|
| 147 |
Q |
A |
-0.9682 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.7903 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.9049 |
|
| 152 |
N |
A |
-1.5654 |
|
| 153 |
A |
A |
-0.3543 |
|
| 154 |
L |
A |
0.5586 |
|
| 155 |
Q |
A |
-0.4555 |
|
| 156 |
S |
A |
-0.7450 |
|
| 157 |
G |
A |
-1.4578 |
|
| 158 |
N |
A |
-1.8945 |
|
| 159 |
S |
A |
-1.8154 |
|
| 160 |
Q |
A |
-2.2878 |
|
| 161 |
E |
A |
-2.1107 |
|
| 162 |
S |
A |
-1.1008 |
|
| 163 |
V |
A |
-0.7294 |
|
| 164 |
T |
A |
-1.2902 |
|
| 165 |
E |
A |
-2.4060 |
|
| 166 |
Q |
A |
-2.2190 |
|
| 167 |
D |
A |
-2.4346 |
|
| 168 |
S |
A |
-2.4673 |
|
| 169 |
K |
A |
-2.6901 |
|
| 170 |
D |
A |
-1.8798 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-1.0630 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.3863 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.6578 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.7865 |
|
| 181 |
L |
A |
-0.9619 |
|
| 182 |
S |
A |
-1.1718 |
|
| 183 |
K |
A |
-2.2286 |
|
| 184 |
A |
A |
-2.0514 |
|
| 185 |
D |
A |
-2.7317 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.8237 |
|
| 188 |
K |
A |
-3.7981 |
|
| 189 |
H |
A |
-3.1491 |
|
| 190 |
K |
A |
-3.1710 |
|
| 191 |
V |
A |
-1.4236 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-1.0618 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.3261 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.5542 |
|
| 200 |
G |
A |
-0.3537 |
|
| 201 |
L |
A |
-0.1899 |
|
| 202 |
S |
A |
-0.4568 |
|
| 203 |
S |
A |
-0.4569 |
|
| 204 |
P |
A |
-0.6320 |
|
| 205 |
V |
A |
-0.0933 |
|
| 206 |
T |
A |
-0.4455 |
|
| 207 |
K |
A |
-0.4240 |
|
| 208 |
S |
A |
-0.3680 |
|
| 209 |
F |
A |
-0.5664 |
|
| 210 |
N |
A |
-1.6166 |
|
| 211 |
R |
A |
-2.4131 |
|
| 212 |
G |
A |
-1.4270 |
|
| 213 |
A |
A |
-0.7429 |
|