Project name: 4eje modified

Chain sequence(s)	A: VSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIPVPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRP; C: ILPTAPPEY
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.2618
• Maximal score value: 2.399
• Average score: -0.756
• Total score value: -114.9087

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
3	V	A	1.0360
4	S	A	-0.2988
5	E	A	-1.7055
6	S	A	-1.6714
7	Q	A	-1.7486
8	L	A	0.0000
9	K	A	-3.2618
10	K	A	-2.9540
11	M	A	-1.6174
12	V	A	0.0000
13	S	A	-2.5958
14	K	A	-2.9464
15	Y	A	0.0000
16	K	A	-2.5487
17	Y	A	-1.5728
18	R	A	-3.0674
19	D	A	-2.7371
20	L	A	-1.2900
21	T	A	0.0000
22	V	A	0.0000
23	R	A	-2.3290
24	E	A	-1.3027
25	T	A	0.0000
26	V	A	-0.5412
27	N	A	-0.8313
28	V	A	0.0000
29	I	A	-0.1988
30	T	A	0.1769
31	L	A	0.9331
32	Y	A	-0.3607
33	K	A	-1.4155
34	D	A	-0.8862
35	L	A	0.0000
36	K	A	-1.6237
37	P	A	0.0000
38	V	A	0.1543
39	L	A	-0.3122
40	D	A	-1.9556
41	S	A	-1.6750
42	Y	A	-0.3925
43	V	A	0.6095
44	F	A	-0.1576
45	N	A	-1.6325
46	D	A	-2.1988
47	G	A	-1.2748
48	S	A	-0.8684
49	S	A	-1.2982
50	R	A	-2.6305
51	E	A	-3.0813
52	L	A	0.0000
53	M	A	0.0000
54	N	A	0.0000
55	L	A	0.0000
56	T	A	-0.7641
57	G	A	-0.6624
58	T	A	0.0000
59	I	A	0.0000
60	P	A	-0.3981
61	V	A	0.0000
62	P	A	-1.1439
63	Y	A	-1.8656
64	R	A	-2.6767
65	G	A	-1.9877
66	N	A	-2.0737
67	T	A	-1.1817
68	Y	A	-0.3084
69	N	A	0.3133
70	I	A	0.0000
71	P	A	0.0000
72	I	A	0.0000
73	C	A	0.0000
74	L	A	0.0000
75	W	A	0.2896
76	L	A	0.0000
77	L	A	-0.5245
78	D	A	-1.5340
79	T	A	-0.8427
80	Y	A	0.0000
81	P	A	0.0000
82	Y	A	0.0493
83	N	A	-0.9014
84	P	A	-0.9443
85	P	A	0.0000
86	I	A	0.3776
87	C	A	0.0000
88	F	A	-0.5143
89	V	A	0.0000
90	K	A	-1.8318
91	P	A	-1.0210
92	T	A	-0.6565
93	S	A	-0.7988
94	S	A	-0.9520
95	M	A	0.0000
96	T	A	-0.8734
97	I	A	-1.0252
98	K	A	-1.4583
99	T	A	-1.5493
100	G	A	-1.8973
101	K	A	-2.0116
102	H	A	-1.5229
103	V	A	0.0000
104	D	A	-1.5780
105	A	A	-1.1471
106	N	A	-1.7298
107	G	A	0.0000
108	K	A	-1.0986
109	I	A	0.0000
110	Y	A	-0.3558
111	L	A	0.0000
112	P	A	-0.8577
113	Y	A	-0.9026
114	L	A	0.0000
115	H	A	-2.1436
116	E	A	-2.8429
117	W	A	0.0000
118	K	A	-2.7573
119	H	A	-1.5058
120	P	A	-1.3828
121	Q	A	-2.2065
122	S	A	0.0000
123	D	A	-1.0585
124	L	A	0.0000
125	L	A	0.0930
126	G	A	-0.4298
127	L	A	0.0000
128	I	A	0.0000
129	Q	A	-0.1881
130	V	A	0.7398
131	M	A	0.0000
132	I	A	0.4825
133	V	A	1.1921
134	V	A	0.0427
135	F	A	0.0000
136	G	A	-0.9694
137	D	A	-2.4272
138	E	A	-2.5987
139	P	A	0.0000
140	P	A	0.0000
141	V	A	0.0000
142	F	A	-0.9504
143	S	A	-1.3456
144	R	A	-2.2736
145	P	A	-1.3361
1	I	C	2.3990
2	L	C	2.3938
3	P	C	0.8543
4	T	C	0.4783
5	A	C	0.0000
6	P	C	0.0000
7	P	C	-1.0958
8	E	C	-1.6120
9	Y	C	0.1737