Project name: 5vkk:H

Chain sequence(s)	H: VQLVQSGAEVKKPGSSVKVSCKASGYTFTSYWLHWVRQAPGQGLEWIGYINPRNDYTEYNQNFKDKATITADESTNTAYMELSSLRSEDTAFYFCARRDITTFYWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.4988
• Maximal score value: 2.4419
• Average score: -0.5719
• Total score value: -124.6844

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	H	1.2070
3	Q	H	-0.0075
4	L	H	0.0000
5	V	H	0.7346
6	Q	H	0.0000
7	S	H	-0.5315
8	G	H	-0.5774
9	A	H	-0.2512
10	E	H	-0.4764
11	V	H	-0.0054
12	K	H	-1.3100
13	K	H	-2.2892
14	P	H	-1.8454
15	G	H	-1.5491
16	S	H	-1.2476
17	S	H	-1.4029
18	V	H	0.0000
19	K	H	-2.1528
20	V	H	0.0000
21	S	H	-0.5552
22	C	H	0.0000
23	K	H	-1.0154
24	A	H	0.0000
25	S	H	-0.2658
26	G	H	0.0715
27	Y	H	0.1757
28	T	H	-0.2208
29	F	H	0.0000
30	T	H	0.0000
31	S	H	-0.3687
32	Y	H	-0.0323
33	W	H	0.0311
34	L	H	0.0000
35	H	H	-0.1206
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0146
39	Q	H	-0.2103
40	A	H	-0.8362
41	P	H	-1.0349
42	G	H	-1.2935
43	Q	H	-1.4967
44	G	H	-0.7100
45	L	H	0.7866
46	E	H	-0.2836
47	W	H	0.1112
48	I	H	0.0000
49	G	H	0.0000
50	Y	H	0.0000
51	I	H	0.0000
52	N	H	-1.2205
52A	P	H	0.0000
53	R	H	-3.1741
54	N	H	-2.9361
55	D	H	-2.7060
56	Y	H	-0.7287
57	T	H	-0.5640
58	E	H	-1.1716
59	Y	H	-1.4684
60	N	H	-1.6626
61	Q	H	-2.6977
62	N	H	-2.7427
63	F	H	0.0000
64	K	H	-3.4988
65	D	H	-3.1586
66	K	H	-2.1019
67	A	H	0.0000
68	T	H	-1.2184
69	I	H	0.0000
70	T	H	-0.6903
71	A	H	-1.7494
72	D	H	-2.5283
73	E	H	-3.2880
74	S	H	-1.5897
75	T	H	-1.4871
76	N	H	-2.0470
77	T	H	0.0000
78	A	H	0.0000
79	Y	H	-0.6588
80	M	H	0.0000
81	E	H	-1.6811
82	L	H	0.0000
82A	S	H	-1.4002
82B	S	H	-1.3391
82C	L	H	0.0000
83	R	H	-2.7333
84	S	H	-2.1862
85	E	H	-2.4163
86	D	H	0.0000
87	T	H	-0.8838
88	A	H	0.0000
89	F	H	0.5311
90	Y	H	0.0000
91	F	H	0.4846
92	C	H	0.0000
93	A	H	0.0000
94	R	H	0.0000
95	R	H	-0.4471
96	D	H	0.4911
97	I	H	1.7367
98	T	H	0.8812
99	T	H	0.9143
101	F	H	1.5247
102	Y	H	0.8279
103	W	H	0.6074
104	G	H	0.0000
105	Q	H	-0.7749
106	G	H	-0.1599
107	T	H	0.0000
108	T	H	0.1528
109	V	H	0.0000
110	T	H	-0.6151
111	V	H	0.0000
112	S	H	-1.2199
113	S	H	-1.1179
115	A	H	-0.6134
116	S	H	-0.6628
117	T	H	-0.5993
118	K	H	-1.1821
119	G	H	-1.4391
120	P	H	0.0000
121	S	H	0.0647
122	V	H	0.2928
123	F	H	1.1852
124	P	H	0.2521
125	L	H	0.4620
126	A	H	-1.0167
127	P	H	0.0000
128	S	H	0.0000
129	S	H	-1.2479
130	K	H	-1.9296
131	S	H	-0.8823
132	T	H	-1.0004
133	S	H	-0.9355
134	G	H	-0.8828
135	G	H	-0.9187
136	T	H	-0.6627
137	A	H	0.0000
138	A	H	-0.1575
139	L	H	0.0000
140	G	H	0.0000
141	C	H	0.0000
142	L	H	0.8176
143	V	H	0.0000
144	K	H	-0.1530
145	D	H	-0.4198
146	Y	H	0.0000
147	F	H	0.0000
148	P	H	-0.7815
149	E	H	-0.9715
150	P	H	-0.9911
151	V	H	-0.8052
152	T	H	-0.6142
153	V	H	-0.3958
154	S	H	-0.3549
155	W	H	0.0000
156	N	H	-0.7721
157	S	H	-0.6684
158	G	H	-0.5147
159	A	H	-0.2659
160	L	H	-0.0313
161	T	H	-0.3103
162	S	H	-0.3695
163	G	H	-0.4855
164	V	H	-0.0270
165	H	H	-0.4665
166	T	H	0.2541
167	F	H	1.1562
168	P	H	0.8227
169	A	H	1.2301
170	V	H	2.4419
171	L	H	2.1018
172	Q	H	0.6797
173	S	H	0.0927
174	S	H	-0.2122
175	G	H	0.2236
176	L	H	0.2194
177	Y	H	0.6825
178	S	H	0.0000
179	L	H	0.0000
180	S	H	0.7452
181	S	H	0.0000
182	V	H	0.4526
183	V	H	0.0000
184	T	H	-0.2737
185	V	H	0.0000
186	P	H	-0.7024
187	S	H	-0.6040
188	S	H	-0.5823
189	S	H	-0.6624
190	L	H	-0.9001
191	G	H	-1.3106
192	T	H	-0.7990
193	Q	H	-1.4266
194	T	H	-1.2124
195	Y	H	0.0000
196	I	H	-1.2832
197	C	H	0.0000
198	N	H	0.0000
199	V	H	0.0000
200	N	H	-1.9405
201	H	H	0.0000
202	K	H	-2.8415
203	P	H	-1.7386
204	S	H	-1.8780
205	N	H	-2.6460
206	T	H	-2.0858
207	K	H	-2.6098
208	V	H	-1.4370
209	D	H	-2.4503
210	K	H	-2.0143
211	R	H	-2.4504
212	V	H	0.0000
213	E	H	-2.8360
214	P	H	-1.9530
215	K	H	-2.2433
216	S	H	-1.1067
217	C	H	-0.2624