Project name: 4jlr:H

Chain sequence(s)	H: QVTLRESGPALVKPTQTLTLTCTFSGFSLSTAGMSVGWIRQPPGKALEWLADIWWDDKKHYNPSLKDRLTISKDTSANQVVLKVTNMDPADTATYYCARDMIFNFYFDVWGQGTTVTVSSASTKGPSVFPLAPSSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.2358
• Maximal score value: 3.269
• Average score: -0.4764
• Total score value: -102.4154

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.1550
2	V	H	-0.3812
3	T	H	-0.7025
4	L	H	0.0000
5	R	H	-2.1750
6	E	H	0.0000
7	S	H	-0.7543
8	G	H	-0.4121
9	P	H	-0.4276
10	A	H	-0.4190
11	L	H	-0.2609
12	V	H	0.0000
13	K	H	-1.9890
14	P	H	-1.7505
15	T	H	-1.7687
16	Q	H	-1.9716
17	T	H	-1.4780
18	L	H	0.0000
19	T	H	-0.5621
20	L	H	0.0000
21	T	H	-0.5470
22	C	H	0.0000
23	T	H	-1.0496
24	F	H	0.0000
25	S	H	-0.8192
26	G	H	-0.7288
27	F	H	-0.2473
28	S	H	-0.1850
29	L	H	0.0000
30	S	H	-0.7273
31	T	H	-0.2109
32	A	H	-0.0482
33	G	H	0.0000
34	M	H	0.4955
35	S	H	0.0000
35A	V	H	0.0000
35B	G	H	0.0000
36	W	H	0.0000
37	I	H	0.0000
38	R	H	-0.3427
39	Q	H	-0.7503
40	P	H	-0.9643
41	P	H	-1.0199
42	G	H	-1.3547
43	K	H	-1.9385
44	A	H	-0.6261
45	L	H	0.2857
46	E	H	-0.3814
47	W	H	0.2353
48	L	H	0.0000
49	A	H	0.0000
50	D	H	0.0000
51	I	H	0.0000
52	W	H	0.0000
53	W	H	-1.4730
54	D	H	-2.8981
55	D	H	-3.2142
56	K	H	-3.2358
57	K	H	-2.0843
58	H	H	-0.8365
59	Y	H	-0.4970
60	N	H	-0.8291
61	P	H	-1.3668
62	S	H	-1.2097
63	L	H	0.0000
64	K	H	-2.7814
65	D	H	-2.7988
66	R	H	-2.1439
67	L	H	0.0000
68	T	H	-0.7236
69	I	H	0.0000
70	S	H	-1.1481
71	K	H	-1.4226
72	D	H	-1.8867
73	T	H	-1.1398
74	S	H	-0.8780
75	A	H	-0.8530
76	N	H	-1.0423
77	Q	H	-1.2933
78	V	H	0.0000
79	V	H	-0.3670
80	L	H	0.0000
81	K	H	-0.9124
82	V	H	0.0000
82A	T	H	-1.6551
82B	N	H	-2.1400
82C	M	H	0.0000
83	D	H	-1.8541
84	P	H	-0.9460
85	A	H	-0.3942
86	D	H	0.0000
87	T	H	-0.3766
88	A	H	0.0000
89	T	H	-0.2548
90	Y	H	0.0000
91	Y	H	-0.2205
92	C	H	0.0000
93	A	H	0.0000
94	R	H	0.0000
95	D	H	0.0000
96	M	H	2.1194
97	I	H	2.8291
98	F	H	3.0925
99	N	H	2.4350
100	F	H	3.2690
100A	Y	H	2.5704
100B	F	H	1.0476
101	D	H	-0.1813
102	V	H	0.1755
103	W	H	-0.1036
104	G	H	0.0000
105	Q	H	-1.4822
106	G	H	-0.9383
107	T	H	-0.6824
108	T	H	-0.4035
109	V	H	0.0000
110	T	H	-0.4205
111	V	H	0.0000
112	S	H	-0.7950
113	S	H	-0.7152
114	A	H	-0.5249
115	S	H	-0.6907
116	T	H	-0.9207
117	K	H	-1.6000
118	G	H	-1.7100
119	P	H	0.0000
120	S	H	-0.2181
121	V	H	0.0000
122	F	H	1.1165
123	P	H	0.1898
124	L	H	0.5808
125	A	H	-0.3594
126	P	H	-0.4214
127	S	H	-0.5361
128	S	H	-0.3538
134	G	H	-0.6431
135	T	H	-0.4809
136	A	H	-0.2975
137	A	H	0.0927
138	L	H	0.0000
139	G	H	0.0000
140	C	H	0.0000
141	L	H	0.7156
142	V	H	0.0000
143	K	H	-0.3067
144	D	H	-1.0371
145	Y	H	0.0000
146	F	H	0.0000
147	P	H	0.0000
148	E	H	-0.4805
149	P	H	-0.7842
150	V	H	-0.8186
151	T	H	-0.7288
152	V	H	-0.4473
153	S	H	-0.3280
154	W	H	0.0000
155	N	H	-0.6912
156	S	H	-0.5873
157	G	H	-0.5676
158	A	H	-0.2537
159	L	H	-0.0332
160	T	H	-0.3238
161	S	H	-0.3829
162	G	H	-0.4952
163	V	H	-0.0374
164	H	H	-0.5018
165	T	H	0.1133
166	F	H	0.9494
167	P	H	0.5393
168	A	H	1.2355
169	V	H	2.4035
170	L	H	1.8696
171	Q	H	0.5593
172	S	H	0.0397
173	S	H	-0.3136
174	G	H	0.1185
175	L	H	0.0722
176	Y	H	0.6393
177	S	H	0.0000
178	L	H	0.0000
179	S	H	0.6500
180	S	H	0.0000
181	V	H	0.4086
182	V	H	0.0000
183	T	H	-0.2453
184	V	H	0.0000
185	P	H	-0.5136
186	S	H	-0.5634
187	S	H	-0.5993
188	S	H	-0.5945
189	L	H	-0.8341
190	G	H	-1.0944
191	T	H	-0.9010
192	Q	H	-1.1857
193	T	H	-1.0837
194	Y	H	0.0000
195	I	H	-1.0581
196	C	H	0.0000
197	N	H	0.0000
198	V	H	0.0000
199	N	H	-2.3427
200	H	H	0.0000
201	K	H	-2.8923
202	P	H	-1.6881
203	S	H	-1.9801
204	N	H	-2.7423
205	T	H	-2.2891
206	K	H	-2.7476
207	V	H	-1.5549
208	D	H	-2.0545
209	K	H	-1.5983
210	K	H	-2.2201
211	V	H	0.0000
212	E	H	-2.4719
213	P	H	-1.3861