Project name: 5nhw:H

Chain sequence(s)	H: VQLVQSGAEVKKPGASVKVSCKASGYTFTSSYINWVRQAPGQGLEWMGTINPVSGSTSYAQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCARGGWFDYWGQGTLVTVSSASTKGPSVFPLAPTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSEF
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.3563
• Maximal score value: 2.5155
• Average score: -0.4398
• Total score value: -92.3635

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	H	0.3181
3	Q	H	-0.7872
4	L	H	0.0000
5	V	H	-0.3521
6	Q	H	-0.5202
7	S	H	-0.7694
8	G	H	-0.6707
9	A	H	-0.0071
10	E	H	-0.2946
11	V	H	0.8405
12	K	H	-0.8593
13	K	H	-2.1826
14	P	H	-2.2613
15	G	H	-2.0134
16	A	H	-1.4292
17	S	H	-1.7708
18	V	H	0.0000
19	K	H	-2.1076
20	V	H	0.0000
21	S	H	-0.7480
22	C	H	0.0000
23	K	H	-0.9170
24	A	H	0.0000
25	S	H	-0.4167
26	G	H	-0.3454
27	Y	H	-0.0379
28	T	H	-0.0699
29	F	H	0.0000
30	T	H	0.4692
31	S	H	0.2067
32	S	H	0.5370
33	Y	H	0.9812
34	I	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.1319
39	Q	H	-0.2632
40	A	H	-0.9033
41	P	H	-0.9242
42	G	H	-1.1760
43	Q	H	-1.5633
44	G	H	-0.5921
45	L	H	0.8732
46	E	H	0.1231
47	W	H	0.3700
48	M	H	0.0000
49	G	H	0.0000
50	T	H	0.0698
51	I	H	0.0000
52	N	H	0.2047
53	P	H	0.0000
54	V	H	1.4160
55	S	H	0.3450
56	G	H	-0.0755
57	S	H	-0.1758
58	T	H	-0.2060
59	S	H	-0.4320
60	Y	H	-0.7261
61	A	H	0.0000
62	Q	H	-2.3597
63	K	H	-2.6356
64	F	H	0.0000
65	Q	H	-2.3586
66	G	H	-1.7986
67	R	H	-1.6906
68	V	H	0.0000
69	T	H	-0.8016
70	M	H	0.0000
71	T	H	-0.6108
72	R	H	-0.6105
73	D	H	-0.5249
74	T	H	0.1134
75	S	H	0.4001
76	I	H	1.3364
77	S	H	0.1592
78	T	H	0.0000
79	A	H	0.0000
80	Y	H	-0.8228
81	M	H	0.0000
82	E	H	-1.5146
83	L	H	0.0000
84	S	H	-1.8701
85	R	H	-2.7547
86	L	H	0.0000
87	R	H	-3.3563
88	S	H	-2.3720
89	D	H	-2.5561
90	D	H	0.0000
91	T	H	-0.7608
92	A	H	0.0000
93	V	H	0.5208
94	Y	H	0.0000
95	Y	H	0.3677
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.2600
99	G	H	0.0000
100	G	H	0.2255
101	W	H	0.9362
102	F	H	0.6821
103	D	H	-0.1863
104	Y	H	0.4491
105	W	H	0.3624
106	G	H	0.0000
107	Q	H	-0.9087
108	G	H	0.0000
109	T	H	0.0000
110	L	H	0.5149
111	V	H	0.0000
112	T	H	-0.2307
113	V	H	0.0000
114	S	H	-1.1206
115	S	H	-0.7552
116	A	H	-0.4976
117	S	H	-0.4174
118	T	H	-0.7188
119	K	H	-1.0476
120	G	H	-1.3914
121	P	H	0.0000
122	S	H	-0.1442
123	V	H	0.0000
124	F	H	0.7681
125	P	H	-0.1145
126	L	H	0.1193
127	A	H	-0.9874
128	P	H	-0.7247
137	T	H	-0.2693
138	A	H	-0.1654
139	A	H	0.1175
140	L	H	0.0000
141	G	H	0.0000
142	C	H	0.0000
143	L	H	0.6422
144	V	H	0.0000
145	K	H	-0.1303
146	D	H	-0.3456
147	Y	H	0.0000
148	F	H	-0.2653
149	P	H	-0.6469
150	E	H	-1.0458
151	P	H	-1.1462
152	V	H	0.0000
153	T	H	-0.7285
154	V	H	-0.4737
155	S	H	-0.3844
156	W	H	0.0000
157	N	H	-0.7561
158	S	H	-0.6601
159	G	H	-0.5807
160	A	H	-0.2446
161	L	H	-0.0269
162	T	H	-0.3122
163	S	H	-0.3834
164	G	H	-0.5111
165	V	H	0.0159
166	H	H	-0.4014
167	T	H	0.2511
168	F	H	1.1744
169	P	H	0.7883
170	A	H	1.2736
171	V	H	2.5155
172	L	H	2.1391
173	Q	H	0.8523
174	S	H	-0.4409
175	S	H	-0.3970
176	G	H	0.2789
177	L	H	0.3623
178	Y	H	0.8162
179	S	H	0.0000
180	L	H	0.0000
181	S	H	0.7406
182	S	H	0.0000
183	V	H	0.5246
184	V	H	0.0000
185	T	H	-0.2536
186	V	H	0.0000
187	P	H	-0.4593
188	S	H	-0.4595
189	S	H	-0.5447
190	S	H	-0.5815
191	L	H	-0.9384
192	G	H	-0.9452
193	T	H	-0.6382
194	Q	H	-1.0464
195	T	H	-1.0583
196	Y	H	0.0000
197	I	H	-1.3373
198	C	H	0.0000
199	N	H	-1.5426
200	V	H	0.0000
201	N	H	-1.9538
202	H	H	0.0000
203	K	H	-2.8556
204	P	H	-1.7166
205	S	H	-1.7807
206	N	H	-2.5782
207	T	H	-2.0802
208	K	H	-2.7233
209	V	H	-1.7188
210	D	H	-2.5813
211	K	H	-2.1970
212	K	H	-2.5177
213	V	H	0.0000
214	E	H	-2.8287
215	P	H	-2.2643
216	K	H	-2.4048
217	S	H	-1.7699
218	E	H	-1.4108
219	F	H	0.7862