Project name: 5ggv:H

Chain sequence(s)	H: QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVIWYDGSNKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDPRGATLYYYYYGMDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.7478
• Maximal score value: 2.9786
• Average score: -0.4517
• Total score value: -101.6322

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.2263
2	V	H	-0.4209
3	Q	H	-0.8691
4	L	H	0.0000
5	V	H	0.2380
6	E	H	0.0000
7	S	H	-0.6269
8	G	H	-0.9184
9	G	H	-0.6106
10	G	H	-0.0902
11	V	H	0.2870
12	V	H	0.0000
13	Q	H	-1.6812
14	P	H	-1.9408
15	G	H	-2.0612
16	R	H	-2.7207
17	S	H	-2.0381
18	L	H	-1.4371
19	R	H	-2.0349
20	L	H	0.0000
21	S	H	-0.5037
22	C	H	0.0000
23	A	H	-0.3825
24	A	H	0.0000
25	S	H	-0.6311
26	G	H	-0.7045
27	F	H	-0.2322
28	T	H	-0.0480
29	F	H	0.0000
30	S	H	-0.6348
31	S	H	-0.1957
32	Y	H	-0.0792
33	G	H	0.0000
34	M	H	0.0000
35	H	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.5503
40	A	H	-1.1621
41	P	H	-0.9593
42	G	H	-1.4477
43	K	H	-2.0942
44	G	H	-0.9694
45	L	H	0.5440
46	E	H	-0.2765
47	W	H	0.2057
48	V	H	0.0000
49	A	H	0.0000
50	V	H	0.0000
51	I	H	0.0000
52	W	H	-0.2988
53	Y	H	-0.0471
54	D	H	-1.2452
55	G	H	-1.0926
56	S	H	-1.0395
57	N	H	-1.1465
58	K	H	-0.4804
59	Y	H	0.2704
60	Y	H	-0.3963
61	A	H	-1.0341
62	D	H	-2.2527
63	S	H	-1.7576
64	V	H	0.0000
65	K	H	-2.4554
66	G	H	-1.7984
67	R	H	-1.3964
68	F	H	0.0000
69	T	H	-0.7516
70	I	H	0.0000
71	S	H	-0.4993
72	R	H	-0.9535
73	D	H	-1.7074
74	N	H	-1.8252
75	S	H	-1.6335
76	K	H	-2.4878
77	N	H	-1.9730
78	T	H	-1.1573
79	L	H	0.0000
80	Y	H	-0.4444
81	L	H	0.0000
82	Q	H	-1.1105
83	M	H	0.0000
84	N	H	-1.9020
85	S	H	-1.7868
86	L	H	0.0000
87	R	H	-2.4539
88	A	H	-1.6439
89	E	H	-2.2234
90	D	H	0.0000
91	T	H	-0.7965
92	A	H	0.0000
93	V	H	0.1432
94	Y	H	0.0000
95	Y	H	0.2543
96	C	H	0.0000
97	A	H	0.0000
98	R	H	-0.2107
99	D	H	0.0000
100	P	H	0.0000
101	R	H	-0.4731
102	G	H	1.1961
103	A	H	0.8761
104	T	H	1.3937
105	L	H	2.5947
106	Y	H	2.9786
107	Y	H	2.7777
108	Y	H	2.6790
109	Y	H	2.1144
110	Y	H	1.3004
111	G	H	0.2020
112	M	H	0.0193
113	D	H	-0.2980
114	V	H	-0.0421
115	W	H	0.1496
116	G	H	-0.2605
117	Q	H	-1.0054
118	G	H	-0.4132
119	T	H	-0.3181
120	T	H	-0.2713
121	V	H	0.0000
122	T	H	-0.4018
123	V	H	0.0000
124	S	H	-0.7020
125	S	H	-0.4913
126	A	H	-0.3662
127	S	H	-0.4675
128	T	H	-0.5917
129	K	H	-1.0603
130	G	H	-1.3371
131	P	H	0.0000
132	S	H	-0.0432
133	V	H	0.0000
134	F	H	0.9308
135	P	H	0.0385
136	L	H	0.5061
137	A	H	-0.6678
138	P	H	0.0000
139	S	H	-1.0210
140	S	H	-1.1769
141	K	H	-1.8995
142	S	H	-1.0040
143	T	H	-1.0181
144	S	H	-0.9659
145	G	H	-0.8372
146	G	H	-0.8871
147	T	H	-0.6596
148	A	H	0.0000
149	A	H	-0.2136
150	L	H	0.0000
151	G	H	0.0000
152	C	H	0.0000
153	L	H	0.7576
154	V	H	0.0000
155	K	H	-0.1791
156	D	H	-0.3488
157	Y	H	0.0000
158	F	H	0.0000
159	P	H	-0.6762
160	E	H	-1.0621
161	P	H	-1.1270
162	V	H	-0.6042
163	T	H	-0.5576
164	V	H	-0.2139
165	S	H	-0.3483
166	W	H	0.0000
167	N	H	-0.7333
168	S	H	-0.6541
169	G	H	-0.5150
170	A	H	-0.2352
171	L	H	0.0147
172	T	H	-0.2768
173	S	H	-0.3519
174	G	H	-0.4413
175	V	H	0.0585
176	H	H	-0.3302
177	T	H	0.2551
178	F	H	1.0804
179	P	H	0.7067
180	A	H	1.2304
181	V	H	2.4995
182	L	H	2.1346
183	Q	H	0.7365
184	S	H	0.1218
185	S	H	-0.1625
186	G	H	0.2600
187	L	H	0.2501
188	Y	H	0.7145
189	S	H	0.0000
190	L	H	0.9812
191	S	H	0.7528
192	S	H	0.0000
193	V	H	0.4749
194	V	H	0.0000
195	T	H	-0.2319
196	V	H	0.0000
197	P	H	-0.5514
198	S	H	-0.5930
199	S	H	-0.5530
200	S	H	-0.5785
201	L	H	-0.7709
202	G	H	-1.0568
203	T	H	-0.6936
204	Q	H	-1.1772
205	T	H	-1.0787
206	Y	H	0.0000
207	I	H	-1.2740
208	C	H	0.0000
209	N	H	-1.4401
210	V	H	0.0000
211	N	H	-1.7162
212	H	H	0.0000
213	K	H	-2.7478
214	P	H	-1.6978
215	S	H	-1.8037
216	N	H	-2.4964
217	T	H	-2.0039
218	K	H	-2.5864
219	V	H	-1.5864
220	D	H	-2.5530
221	K	H	-1.9495
222	K	H	-2.3688
223	V	H	0.0000
224	E	H	-2.4222
225	P	H	-1.1696