Project name: 5sx5:J
Status: done
submitted: 2019-03-20 20:00:48, status changed: 2019-03-20 20:10:53
Settings
|
Chain sequence(s)
|
J: QVQLQESGPGLVKPSETLSLTCTVSGGSVSSGDYYWTWIRQSPGKGLEWIGHIYYSGNTNYNPSLKSRLTISIDTSKTQFSLKLSSVTAADTAIYYCVRDRVTGAFDIWGQGTMVTVSSASTKGPSVFPLAPCSSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPQTYTCNVDHKPSNTKVDKTVE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.7353
-
Maximal score value
-
2.5001
-
Average score
-
-0.4855
-
Total score value
-
-100.4992
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
J |
-1.5706 |
|
| 2 |
V |
J |
-1.2435 |
|
| 3 |
Q |
J |
-1.8733 |
|
| 4 |
L |
J |
0.0000 |
|
| 5 |
Q |
J |
-1.6410 |
|
| 6 |
E |
J |
0.0000 |
|
| 7 |
S |
J |
-0.6547 |
|
| 8 |
G |
J |
-0.6377 |
|
| 9 |
P |
J |
-0.6134 |
|
| 10 |
G |
J |
-0.4218 |
|
| 11 |
L |
J |
-0.3895 |
|
| 12 |
V |
J |
0.0000 |
|
| 13 |
K |
J |
-2.4104 |
|
| 14 |
P |
J |
-1.7080 |
|
| 15 |
S |
J |
-1.7008 |
|
| 16 |
E |
J |
-2.5936 |
|
| 17 |
T |
J |
-1.6577 |
|
| 18 |
L |
J |
0.0000 |
|
| 19 |
S |
J |
-0.9203 |
|
| 20 |
L |
J |
0.0000 |
|
| 21 |
T |
J |
-0.6209 |
|
| 22 |
C |
J |
0.0000 |
|
| 23 |
T |
J |
-1.0873 |
|
| 24 |
V |
J |
0.0000 |
|
| 25 |
S |
J |
-1.4220 |
|
| 26 |
G |
J |
-1.2845 |
|
| 27 |
G |
J |
-1.0346 |
|
| 28 |
S |
J |
-0.8243 |
|
| 29 |
V |
J |
0.0000 |
|
| 30 |
S |
J |
-0.3396 |
|
| 31 |
S |
J |
-0.5449 |
|
| 32 |
G |
J |
-0.7627 |
|
| 33 |
D |
J |
-1.6536 |
|
| 34 |
Y |
J |
-0.6088 |
|
| 35 |
Y |
J |
0.0409 |
|
| 36 |
W |
J |
0.0000 |
|
| 37 |
T |
J |
0.0000 |
|
| 38 |
W |
J |
0.0000 |
|
| 39 |
I |
J |
0.0000 |
|
| 40 |
R |
J |
0.0000 |
|
| 41 |
Q |
J |
-0.2387 |
|
| 42 |
S |
J |
-0.6579 |
|
| 43 |
P |
J |
-0.9414 |
|
| 44 |
G |
J |
-1.3875 |
|
| 45 |
K |
J |
-1.9296 |
|
| 46 |
G |
J |
-0.7594 |
|
| 47 |
L |
J |
0.7577 |
|
| 48 |
E |
J |
0.0608 |
|
| 49 |
W |
J |
0.4856 |
|
| 50 |
I |
J |
0.0000 |
|
| 51 |
G |
J |
0.0000 |
|
| 52 |
H |
J |
-0.4609 |
|
| 53 |
I |
J |
0.0000 |
|
| 54 |
Y |
J |
-0.1166 |
|
| 55 |
Y |
J |
0.3327 |
|
| 56 |
S |
J |
-0.2846 |
|
| 57 |
G |
J |
-0.7391 |
|
| 58 |
N |
J |
-1.5921 |
|
| 59 |
T |
J |
-1.1798 |
|
| 60 |
N |
J |
-1.7042 |
|
| 61 |
Y |
J |
-1.1750 |
|
| 62 |
N |
J |
-1.0489 |
|
| 63 |
P |
J |
-1.2892 |
|
| 64 |
S |
J |
-0.9223 |
|
| 65 |
L |
J |
0.0000 |
|
| 66 |
K |
J |
-2.2559 |
|
| 67 |
S |
J |
-1.3520 |
|
| 68 |
R |
J |
-1.3098 |
|
| 69 |
L |
J |
0.0000 |
|
| 70 |
T |
J |
-0.9300 |
|
| 71 |
I |
J |
0.0000 |
|
| 72 |
S |
J |
-0.4310 |
|
| 73 |
I |
J |
-0.2826 |
|
| 74 |
D |
J |
-1.1789 |
|
| 75 |
T |
J |
-0.9643 |
|
| 76 |
S |
J |
-1.3519 |
|
| 77 |
K |
J |
-2.1176 |
|
| 78 |
T |
J |
-1.4095 |
|
| 79 |
Q |
J |
-1.2175 |
|
| 80 |
F |
J |
0.0000 |
|
| 81 |
S |
J |
-0.5160 |
|
| 82 |
L |
J |
0.0000 |
|
| 83 |
K |
J |
-1.0897 |
|
| 84 |
L |
J |
0.0000 |
|
| 85 |
S |
J |
-1.2001 |
|
| 86 |
S |
J |
-1.3582 |
|
| 87 |
V |
J |
0.0000 |
|
| 88 |
T |
J |
-0.7297 |
|
| 89 |
A |
J |
-0.2244 |
|
| 90 |
A |
J |
-0.2601 |
|
| 91 |
D |
J |
0.0000 |
|
| 92 |
T |
J |
0.1098 |
|
| 93 |
A |
J |
0.0000 |
|
| 94 |
I |
J |
0.6421 |
|
| 95 |
Y |
J |
0.0000 |
|
| 96 |
Y |
J |
0.0693 |
|
| 97 |
C |
J |
0.0000 |
|
| 98 |
V |
J |
0.0000 |
|
| 99 |
R |
J |
0.0000 |
|
| 100 |
D |
J |
-0.3400 |
|
| 101 |
R |
J |
-0.9936 |
|
| 102 |
V |
J |
-0.2468 |
|
| 103 |
T |
J |
-0.4039 |
|
| 104 |
G |
J |
-0.3971 |
|
| 105 |
A |
J |
-0.1287 |
|
| 106 |
F |
J |
0.4098 |
|
| 107 |
D |
J |
-0.3428 |
|
| 108 |
I |
J |
-0.2843 |
|
| 109 |
W |
J |
-0.1387 |
|
| 110 |
G |
J |
-1.0034 |
|
| 111 |
Q |
J |
-1.4381 |
|
| 112 |
G |
J |
-0.6079 |
|
| 113 |
T |
J |
-0.3043 |
|
| 114 |
M |
J |
0.2039 |
|
| 115 |
V |
J |
0.0000 |
|
| 116 |
T |
J |
0.0000 |
|
| 117 |
V |
J |
0.0000 |
|
| 118 |
S |
J |
-0.7245 |
|
| 119 |
S |
J |
-0.8883 |
|
| 120 |
A |
J |
-0.5585 |
|
| 121 |
S |
J |
-0.6426 |
|
| 122 |
T |
J |
-0.5819 |
|
| 123 |
K |
J |
-1.1124 |
|
| 124 |
G |
J |
-1.3735 |
|
| 125 |
P |
J |
-0.5433 |
|
| 126 |
S |
J |
-0.0686 |
|
| 127 |
V |
J |
0.0000 |
|
| 128 |
F |
J |
1.0524 |
|
| 129 |
P |
J |
0.2873 |
|
| 130 |
L |
J |
0.5584 |
|
| 131 |
A |
J |
-0.0020 |
|
| 132 |
P |
J |
-0.0505 |
|
| 133 |
C |
J |
0.5567 |
|
| 134 |
S |
J |
0.0705 |
|
| 140 |
S |
J |
-0.2804 |
|
| 141 |
T |
J |
-0.2070 |
|
| 142 |
A |
J |
-0.0512 |
|
| 143 |
A |
J |
0.2228 |
|
| 144 |
L |
J |
0.1820 |
|
| 145 |
G |
J |
0.0000 |
|
| 146 |
C |
J |
0.0000 |
|
| 147 |
L |
J |
0.6571 |
|
| 148 |
V |
J |
0.0000 |
|
| 149 |
K |
J |
-0.1508 |
|
| 150 |
D |
J |
-0.5331 |
|
| 151 |
Y |
J |
0.0000 |
|
| 152 |
F |
J |
0.0000 |
|
| 153 |
P |
J |
0.0000 |
|
| 154 |
E |
J |
-0.4535 |
|
| 155 |
P |
J |
-0.6911 |
|
| 156 |
V |
J |
-0.6411 |
|
| 157 |
T |
J |
-0.5487 |
|
| 158 |
V |
J |
-0.3644 |
|
| 159 |
S |
J |
-0.5494 |
|
| 160 |
W |
J |
0.0000 |
|
| 161 |
N |
J |
-0.8635 |
|
| 162 |
S |
J |
-0.8279 |
|
| 163 |
G |
J |
-0.6185 |
|
| 164 |
A |
J |
-0.2941 |
|
| 165 |
L |
J |
-0.0767 |
|
| 166 |
T |
J |
-0.3051 |
|
| 167 |
S |
J |
-0.3184 |
|
| 168 |
G |
J |
-0.3862 |
|
| 169 |
V |
J |
0.0609 |
|
| 170 |
H |
J |
-0.4628 |
|
| 171 |
T |
J |
0.1463 |
|
| 172 |
F |
J |
0.8662 |
|
| 173 |
P |
J |
0.6756 |
|
| 174 |
A |
J |
1.2441 |
|
| 175 |
V |
J |
2.5001 |
|
| 176 |
L |
J |
2.1320 |
|
| 177 |
Q |
J |
0.6802 |
|
| 178 |
S |
J |
0.0680 |
|
| 179 |
S |
J |
-0.2398 |
|
| 180 |
G |
J |
0.1478 |
|
| 181 |
L |
J |
0.3062 |
|
| 182 |
Y |
J |
0.8047 |
|
| 183 |
S |
J |
0.0000 |
|
| 184 |
L |
J |
0.0000 |
|
| 185 |
S |
J |
0.6152 |
|
| 186 |
S |
J |
0.0000 |
|
| 187 |
V |
J |
0.4607 |
|
| 188 |
V |
J |
0.0000 |
|
| 189 |
T |
J |
-0.0674 |
|
| 190 |
V |
J |
0.0488 |
|
| 191 |
P |
J |
-0.2447 |
|
| 198 |
Q |
J |
-1.4025 |
|
| 199 |
T |
J |
-0.9811 |
|
| 200 |
Y |
J |
-0.8006 |
|
| 201 |
T |
J |
-0.9622 |
|
| 202 |
C |
J |
0.0000 |
|
| 203 |
N |
J |
-1.3547 |
|
| 204 |
V |
J |
0.0000 |
|
| 205 |
D |
J |
-1.7797 |
|
| 206 |
H |
J |
0.0000 |
|
| 207 |
K |
J |
-2.7353 |
|
| 208 |
P |
J |
-1.6171 |
|
| 209 |
S |
J |
-1.8216 |
|
| 210 |
N |
J |
-2.5567 |
|
| 211 |
T |
J |
-2.0259 |
|
| 212 |
K |
J |
-2.6327 |
|
| 213 |
V |
J |
-1.4536 |
|
| 214 |
D |
J |
-2.2799 |
|
| 215 |
K |
J |
-1.3910 |
|
| 216 |
T |
J |
-1.0188 |
|
| 217 |
V |
J |
0.0000 |
|
| 218 |
E |
J |
-1.9650 |
|