Project name: 3gbm:H

Chain sequence(s)	H: EVQLVESGAEVKKPGSSVKVSCKASGGPFRSYAISWVRQAPGQGPEWMGGIIPIFGTTKYAPKFQGRVTITADDFAGTVYMELSSLRSEDTAMYYCAKHMGYQVRETMDVWGKGTTVTVSSASTKGPSVFPLAPGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8835
• Maximal score value: 3.072
• Average score: -0.4759
• Total score value: -101.8428

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.9930
2	V	H	-1.1487
3	Q	H	-1.5082
4	L	H	0.0000
5	V	H	0.2551
6	E	H	-0.3931
7	S	H	-0.5489
8	G	H	-0.5085
9	A	H	-0.2537
10	E	H	-0.5896
11	V	H	0.0276
12	K	H	-1.2393
13	K	H	-1.8764
14	P	H	-1.9289
15	G	H	-1.4921
16	S	H	-1.1230
17	S	H	-1.3648
18	V	H	0.0000
19	K	H	-2.1333
20	V	H	0.0000
21	S	H	-0.6936
22	C	H	0.0000
23	K	H	-1.4152
24	A	H	0.0000
25	S	H	-0.9973
26	G	H	-1.0301
27	G	H	0.0613
28	P	H	0.3263
29	F	H	1.7811
30	R	H	0.8299
31	S	H	0.7466
32	Y	H	0.9848
33	A	H	0.0000
34	I	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.9623
40	A	H	-1.2759
41	P	H	-1.1560
42	G	H	-1.3500
43	Q	H	-1.9548
44	G	H	-1.5291
45	P	H	-1.0708
46	E	H	-1.0122
47	W	H	-0.3344
48	M	H	0.0000
49	G	H	0.0000
50	G	H	0.0000
51	I	H	0.0000
52	I	H	0.0000
52A	P	H	0.0000
53	I	H	3.0720
54	F	H	2.8501
55	G	H	1.1088
56	T	H	0.3445
57	T	H	-0.5264
58	K	H	-1.5320
59	Y	H	-1.2104
60	A	H	0.0000
61	P	H	-1.6133
62	K	H	-2.2318
63	F	H	0.0000
64	Q	H	-2.2226
65	G	H	-1.5384
66	R	H	-1.3976
67	V	H	0.0000
68	T	H	-1.0098
69	I	H	0.0000
70	T	H	-0.4755
71	A	H	-0.5162
72	D	H	-0.7567
73	D	H	0.1345
74	F	H	1.5366
75	A	H	0.2686
76	G	H	-0.2525
77	T	H	-0.4610
78	V	H	0.0000
79	Y	H	-0.7698
80	M	H	0.0000
81	E	H	-1.6674
82	L	H	0.0000
82A	S	H	-1.2016
82B	S	H	-1.1702
82C	L	H	0.0000
83	R	H	-2.8835
84	S	H	-2.2691
85	E	H	-2.5114
86	D	H	0.0000
87	T	H	-1.0535
88	A	H	0.0000
89	M	H	0.0304
90	Y	H	0.0000
91	Y	H	0.1162
92	C	H	0.0000
93	A	H	0.0000
94	K	H	0.0000
95	H	H	0.0000
96	M	H	0.4486
97	G	H	0.3034
98	Y	H	1.1680
99	Q	H	-0.6287
100	V	H	-1.2533
100A	R	H	-2.5314
100B	E	H	-2.6812
100C	T	H	-1.5049
100D	M	H	-0.7072
101	D	H	-0.6241
102	V	H	-0.2289
103	W	H	0.2238
104	G	H	0.0000
105	K	H	-1.3040
106	G	H	0.0000
107	T	H	0.0000
108	T	H	0.0337
109	V	H	0.0000
110	T	H	-0.7206
111	V	H	0.0000
112	S	H	-1.0958
113	S	H	-1.0289
114	A	H	-0.5719
115	S	H	-0.6564
116	T	H	-0.6719
117	K	H	-1.1086
118	G	H	-1.4391
119	P	H	-0.6494
120	S	H	-0.1780
121	V	H	0.0000
122	F	H	0.5041
123	P	H	-0.2713
124	L	H	0.2674
125	A	H	-0.4414
126	P	H	-0.4180
136	G	H	-0.5993
137	T	H	-0.4688
138	A	H	-0.2396
139	A	H	0.1166
140	L	H	0.0000
141	G	H	0.0000
142	C	H	0.0000
143	L	H	0.5575
144	V	H	0.0000
145	K	H	-0.4164
146	D	H	-0.4088
147	Y	H	0.0000
148	F	H	0.0000
149	P	H	0.0000
150	E	H	-1.4667
151	P	H	-1.2454
152	V	H	-0.7749
153	T	H	-0.7698
154	V	H	-0.3509
156	S	H	-0.3754
157	W	H	0.0000
162	N	H	-0.6472
163	S	H	-0.5938
164	G	H	-0.5301
165	A	H	-0.1713
166	L	H	0.1153
167	T	H	-0.1933
168	S	H	-0.3327
169	G	H	-0.4550
171	V	H	0.0128
172	H	H	-0.4879
173	T	H	0.2558
174	F	H	1.1243
175	P	H	0.8180
176	A	H	1.2202
177	V	H	2.4853
178	L	H	2.1897
179	Q	H	0.7207
180	S	H	0.0873
182	S	H	-0.2077
183	G	H	0.2197
184	L	H	0.1157
185	Y	H	0.5835
186	S	H	0.6152
187	L	H	0.9326
188	S	H	0.6746
189	S	H	0.0000
190	V	H	0.4743
191	V	H	0.0000
192	T	H	-0.2377
193	V	H	0.0000
194	P	H	-0.4438
195	S	H	-0.4899
196	S	H	-0.5797
197	S	H	-0.6294
198	L	H	-0.8377
199	G	H	-1.1385
200	T	H	-1.0325
203	Q	H	-1.5496
205	T	H	-1.3038
206	Y	H	0.0000
207	I	H	-1.3146
208	C	H	0.0000
209	N	H	-1.4903
210	V	H	0.0000
211	N	H	-2.1579
212	H	H	0.0000
213	K	H	-2.8640
214	P	H	-1.7584
215	S	H	-1.8192
216	N	H	-2.5450
217	T	H	-2.0530
218	K	H	-2.6809
219	V	H	-1.4644
220	D	H	-2.2507
221	K	H	-1.9327
222	R	H	-2.6579
223	V	H	0.0000
226	E	H	-2.5823
227	P	H	-1.1675