Project name: 7c10a8661932063
Status: done
submitted: 2018-12-16 15:42:36, status changed: 2018-12-16 15:52:33
Settings
|
Chain sequence(s)
|
F: PDIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRKAQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
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Minimal score value
-
-4.1568
-
Maximal score value
-
1.1981
-
Average score
-
-1.1384
-
Total score value
-
-216.292
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 15 |
P |
F |
-0.7969 |
|
| 16 |
D |
F |
-0.9763 |
|
| 17 |
I |
F |
0.4746 |
|
| 18 |
K |
F |
-0.8454 |
|
| 19 |
L |
F |
-0.2429 |
|
| 20 |
F |
F |
-0.2752 |
|
| 21 |
G |
F |
-0.8398 |
|
| 22 |
K |
F |
-1.9358 |
|
| 23 |
W |
F |
-0.8246 |
|
| 24 |
S |
F |
-1.1321 |
|
| 25 |
T |
F |
-1.9146 |
|
| 26 |
D |
F |
-3.4997 |
|
| 27 |
D |
F |
-3.7553 |
|
| 28 |
V |
F |
0.0000 |
|
| 29 |
Q |
F |
-2.5920 |
|
| 30 |
I |
F |
-1.4312 |
|
| 31 |
N |
F |
-1.8028 |
|
| 32 |
D |
F |
-1.5421 |
|
| 33 |
I |
F |
0.6303 |
|
| 34 |
S |
F |
0.0290 |
|
| 35 |
L |
F |
-0.3956 |
|
| 36 |
Q |
F |
-1.5088 |
|
| 37 |
D |
F |
-2.3390 |
|
| 38 |
Y |
F |
-1.1504 |
|
| 39 |
I |
F |
0.0000 |
|
| 40 |
A |
F |
-1.3607 |
|
| 41 |
V |
F |
-2.1108 |
|
| 42 |
K |
F |
-3.8816 |
|
| 43 |
E |
F |
-3.7203 |
|
| 44 |
K |
F |
-2.8494 |
|
| 45 |
Y |
F |
-1.3680 |
|
| 46 |
A |
F |
-1.5277 |
|
| 47 |
K |
F |
-1.4705 |
|
| 48 |
Y |
F |
-0.0256 |
|
| 49 |
L |
F |
0.3267 |
|
| 50 |
P |
F |
0.0000 |
|
| 51 |
H |
F |
-0.5857 |
|
| 52 |
S |
F |
-0.5924 |
|
| 53 |
A |
F |
-0.6923 |
|
| 54 |
G |
F |
-1.3280 |
|
| 55 |
R |
F |
-1.9937 |
|
| 56 |
Y |
F |
-1.5663 |
|
| 57 |
A |
F |
-1.3382 |
|
| 58 |
A |
F |
-1.2756 |
|
| 59 |
K |
F |
-2.0923 |
|
| 60 |
R |
F |
-2.0042 |
|
| 61 |
F |
F |
-0.3176 |
|
| 62 |
R |
F |
-2.0876 |
|
| 63 |
K |
F |
-2.0013 |
|
| 64 |
A |
F |
0.0000 |
|
| 65 |
Q |
F |
-1.2499 |
|
| 66 |
C |
F |
0.0000 |
|
| 67 |
P |
F |
-0.4505 |
|
| 68 |
I |
F |
0.0000 |
|
| 69 |
V |
F |
-0.1294 |
|
| 70 |
E |
F |
0.0000 |
|
| 71 |
R |
F |
-0.3401 |
|
| 72 |
L |
F |
0.0000 |
|
| 73 |
T |
F |
0.0000 |
|
| 74 |
N |
F |
-0.9592 |
|
| 75 |
S |
F |
0.0000 |
|
| 76 |
M |
F |
0.0000 |
|
| 77 |
M |
F |
-1.6576 |
|
| 78 |
M |
F |
-1.9119 |
|
| 79 |
H |
F |
-2.3344 |
|
| 80 |
G |
F |
-2.6517 |
|
| 81 |
R |
F |
-3.4807 |
|
| 82 |
N |
F |
-3.3259 |
|
| 83 |
N |
F |
-3.2668 |
|
| 84 |
G |
F |
-2.1856 |
|
| 85 |
K |
F |
-2.1004 |
|
| 86 |
K |
F |
-1.0663 |
|
| 87 |
L |
F |
0.2390 |
|
| 88 |
M |
F |
-0.0252 |
|
| 89 |
T |
F |
0.0000 |
|
| 90 |
V |
F |
0.0000 |
|
| 91 |
R |
F |
-1.7472 |
|
| 92 |
I |
F |
-1.1357 |
|
| 93 |
V |
F |
0.0000 |
|
| 94 |
K |
F |
-2.2879 |
|
| 95 |
H |
F |
-2.4143 |
|
| 96 |
A |
F |
0.0000 |
|
| 97 |
F |
F |
-1.4025 |
|
| 98 |
E |
F |
-2.0103 |
|
| 99 |
I |
F |
-0.7303 |
|
| 100 |
I |
F |
0.0000 |
|
| 101 |
H |
F |
-0.7160 |
|
| 102 |
L |
F |
1.1443 |
|
| 103 |
L |
F |
1.1981 |
|
| 104 |
T |
F |
0.2631 |
|
| 105 |
G |
F |
-0.7586 |
|
| 106 |
E |
F |
-2.2842 |
|
| 107 |
N |
F |
-1.8189 |
|
| 108 |
P |
F |
0.0000 |
|
| 109 |
L |
F |
-0.7947 |
|
| 110 |
Q |
F |
-1.2796 |
|
| 111 |
V |
F |
-0.4720 |
|
| 112 |
L |
F |
0.0000 |
|
| 113 |
V |
F |
0.0000 |
|
| 114 |
N |
F |
-0.6000 |
|
| 115 |
A |
F |
0.0000 |
|
| 116 |
I |
F |
0.0000 |
|
| 117 |
I |
F |
-0.0491 |
|
| 118 |
N |
F |
-0.5739 |
|
| 119 |
S |
F |
0.0000 |
|
| 120 |
G |
F |
-1.1126 |
|
| 121 |
P |
F |
0.0000 |
|
| 122 |
R |
F |
-2.5786 |
|
| 123 |
E |
F |
-2.0305 |
|
| 124 |
D |
F |
0.0000 |
|
| 125 |
S |
F |
-1.0040 |
|
| 126 |
T |
F |
-1.5307 |
|
| 127 |
R |
F |
-2.4400 |
|
| 128 |
I |
F |
-1.5545 |
|
| 129 |
G |
F |
-1.6494 |
|
| 130 |
R |
F |
-2.1676 |
|
| 131 |
A |
F |
-1.1396 |
|
| 132 |
G |
F |
-0.8047 |
|
| 133 |
T |
F |
-0.3874 |
|
| 134 |
V |
F |
-0.2143 |
|
| 135 |
R |
F |
-2.4037 |
|
| 136 |
R |
F |
-2.6524 |
|
| 137 |
Q |
F |
-2.7283 |
|
| 138 |
A |
F |
-2.0844 |
|
| 139 |
V |
F |
-0.5257 |
|
| 140 |
D |
F |
-1.6137 |
|
| 141 |
V |
F |
-1.4659 |
|
| 142 |
S |
F |
-1.2057 |
|
| 143 |
P |
F |
-1.1602 |
|
| 144 |
L |
F |
-0.8666 |
|
| 145 |
R |
F |
-1.9432 |
|
| 146 |
R |
F |
0.0000 |
|
| 147 |
V |
F |
0.0000 |
|
| 148 |
N |
F |
-0.7751 |
|
| 149 |
Q |
F |
-0.3665 |
|
| 150 |
A |
F |
0.0000 |
|
| 151 |
I |
F |
0.0000 |
|
| 152 |
W |
F |
0.9559 |
|
| 153 |
L |
F |
0.2667 |
|
| 154 |
L |
F |
0.0000 |
|
| 155 |
C |
F |
0.0000 |
|
| 156 |
T |
F |
-0.2545 |
|
| 157 |
G |
F |
0.0000 |
|
| 158 |
A |
F |
0.0000 |
|
| 159 |
R |
F |
-0.8172 |
|
| 160 |
E |
F |
-1.6737 |
|
| 161 |
A |
F |
-1.2781 |
|
| 162 |
A |
F |
-0.5144 |
|
| 163 |
F |
F |
0.2279 |
|
| 164 |
R |
F |
-1.4369 |
|
| 165 |
N |
F |
-0.8412 |
|
| 166 |
I |
F |
0.8879 |
|
| 167 |
K |
F |
-0.5438 |
|
| 168 |
T |
F |
-0.1315 |
|
| 169 |
I |
F |
-0.1412 |
|
| 170 |
A |
F |
0.0000 |
|
| 171 |
E |
F |
-1.9065 |
|
| 172 |
C |
F |
0.0000 |
|
| 173 |
L |
F |
0.0000 |
|
| 174 |
A |
F |
0.0000 |
|
| 175 |
D |
F |
-2.1821 |
|
| 176 |
E |
F |
0.0000 |
|
| 177 |
L |
F |
0.0000 |
|
| 178 |
I |
F |
-0.5773 |
|
| 179 |
N |
F |
-1.4695 |
|
| 180 |
A |
F |
0.0000 |
|
| 181 |
A |
F |
-1.0259 |
|
| 182 |
K |
F |
-2.0169 |
|
| 183 |
G |
F |
-1.7240 |
|
| 184 |
S |
F |
-1.3896 |
|
| 185 |
S |
F |
-1.9205 |
|
| 186 |
N |
F |
-1.9065 |
|
| 187 |
S |
F |
0.0000 |
|
| 188 |
Y |
F |
-1.2642 |
|
| 189 |
A |
F |
0.0000 |
|
| 190 |
I |
F |
-1.9734 |
|
| 191 |
K |
F |
-3.0820 |
|
| 192 |
K |
F |
-3.0098 |
|
| 193 |
K |
F |
-3.3392 |
|
| 194 |
D |
F |
-4.1568 |
|
| 195 |
E |
F |
-4.1159 |
|
| 196 |
L |
F |
-3.1755 |
|
| 197 |
E |
F |
-3.9659 |
|
| 198 |
R |
F |
-3.9599 |
|
| 199 |
V |
F |
-3.0610 |
|
| 200 |
A |
F |
0.0000 |
|
| 201 |
K |
F |
-3.3559 |
|
| 202 |
S |
F |
-2.6228 |
|
| 203 |
N |
F |
-2.8387 |
|
| 204 |
R |
F |
-2.6568 |
|