Project name: 4llw:A

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASGFTFTDYTMDWVRYAPGKGLEWVADVNPNSGGSIYNQRFKGRFTLSVDRSKNTLYLQMNSLRAEDTAVYYCARNLGPSFYFDYWGQGTLVTVSSASTKGPSVFPLAPGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0463
• Maximal score value: 2.096
• Average score: -0.5377
• Total score value: -114.5335

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.1272
2	V	A	-1.2335
3	Q	A	-1.3207
4	L	A	0.0000
5	V	A	0.5822
6	E	A	0.0000
7	S	A	-0.4560
8	G	A	-0.7951
9	G	A	-0.4212
10	G	A	-0.4339
11	L	A	0.0013
12	V	A	-0.6821
13	Q	A	-1.7211
14	P	A	-1.9241
15	G	A	-1.5806
16	G	A	-1.1320
17	S	A	-1.1554
18	L	A	-1.0478
19	R	A	-2.1562
20	L	A	0.0000
21	S	A	-0.3899
22	C	A	0.0000
23	A	A	-0.3845
24	A	A	0.0000
25	S	A	-1.1471
26	G	A	-1.1611
27	F	A	-0.7162
28	T	A	-0.6614
29	F	A	0.0000
30	T	A	-1.7129
31	D	A	-1.8650
32	Y	A	-0.6630
33	T	A	-0.4121
34	M	A	0.0000
35	D	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	R	A	0.4990
39	Y	A	0.6452
40	A	A	-0.4310
41	P	A	-0.7446
42	G	A	-1.2607
43	K	A	-1.7398
44	G	A	-0.5064
45	L	A	1.0420
46	E	A	0.3498
47	W	A	0.7769
48	V	A	0.0000
49	A	A	0.0000
50	D	A	0.0000
51	V	A	0.0000
52	N	A	-0.9949
53	P	A	0.0000
54	N	A	-2.0452
55	S	A	-1.2494
56	G	A	-1.1705
57	G	A	-0.4502
58	S	A	0.5856
59	I	A	1.5036
60	Y	A	-0.2164
61	N	A	-1.3253
62	Q	A	-2.5505
63	R	A	-3.0463
64	F	A	0.0000
65	K	A	-2.6072
66	G	A	-1.9120
67	R	A	-1.5951
68	F	A	0.0000
69	T	A	-0.7084
70	L	A	0.0000
71	S	A	-0.4624
72	V	A	-0.8722
73	D	A	-1.8114
74	R	A	-2.6763
75	S	A	-2.1024
76	K	A	-2.7778
77	N	A	-2.3090
78	T	A	0.0000
79	L	A	0.0000
80	Y	A	-0.5033
81	L	A	0.0000
82	Q	A	-1.4523
83	M	A	0.0000
84	N	A	-1.4797
85	S	A	-1.4116
86	L	A	0.0000
87	R	A	-2.7949
88	A	A	-1.8532
89	E	A	-2.0263
90	D	A	0.0000
91	T	A	-0.5617
92	A	A	0.0000
93	V	A	0.6997
94	Y	A	0.0000
95	Y	A	0.3605
96	C	A	0.0000
97	A	A	0.0000
98	R	A	0.0000
99	N	A	0.0000
100	L	A	1.5919
101	G	A	0.4841
102	P	A	0.3727
103	S	A	0.9271
104	F	A	1.8886
105	Y	A	2.0960
106	F	A	1.3365
107	D	A	0.5573
108	Y	A	0.6181
109	W	A	0.3687
110	G	A	-0.0876
111	Q	A	-0.8370
112	G	A	0.0000
113	T	A	0.0157
114	L	A	0.4229
115	V	A	0.0000
116	T	A	-0.4568
117	V	A	0.0000
118	S	A	-1.0925
119	S	A	-0.9231
120	A	A	-0.5390
121	S	A	-0.6884
122	T	A	-0.7486
123	K	A	-1.3858
124	G	A	-1.7353
125	P	A	-0.8831
126	S	A	-0.2643
127	V	A	0.0000
128	F	A	0.8228
129	P	A	-0.3183
130	L	A	0.1893
131	A	A	-0.9388
132	P	A	-0.6253
140	G	A	-0.6438
141	T	A	-0.4691
142	A	A	-0.1964
143	A	A	0.0128
144	L	A	0.0000
145	G	A	0.0000
146	C	A	0.0000
147	L	A	0.6679
148	V	A	0.0000
149	K	A	-0.4556
150	D	A	-1.0032
151	Y	A	0.0000
152	F	A	0.0000
153	P	A	0.0000
154	E	A	-0.6629
155	P	A	-0.9421
156	V	A	-1.0124
157	T	A	-0.8592
158	V	A	-0.5529
159	S	A	-0.5134
160	W	A	0.0000
161	N	A	-0.7137
162	S	A	-0.5705
163	G	A	-0.4708
164	A	A	-0.1913
165	L	A	0.0499
166	T	A	-0.2905
167	S	A	-0.3830
168	G	A	-0.5117
169	V	A	-0.0653
170	H	A	-0.4979
171	T	A	0.2741
172	F	A	1.2036
173	P	A	0.7865
174	A	A	1.0300
175	V	A	2.0234
176	L	A	1.4564
177	Q	A	-0.2725
178	S	A	-0.3808
179	S	A	-0.5252
180	G	A	-0.1290
181	L	A	-0.1592
182	Y	A	0.3092
183	S	A	0.3687
184	L	A	0.0000
185	S	A	0.6811
186	S	A	0.0000
187	V	A	0.4237
188	V	A	0.0000
189	T	A	-0.2611
190	V	A	0.0000
191	P	A	-0.5693
192	S	A	-0.5221
193	S	A	-0.5969
194	S	A	-0.5490
195	L	A	-0.7176
196	G	A	-0.9050
197	T	A	-0.6355
198	Q	A	-0.8619
199	T	A	-1.0182
200	Y	A	0.0000
201	I	A	-1.3262
202	C	A	0.0000
203	N	A	-1.5624
204	V	A	0.0000
205	N	A	-2.5478
206	H	A	0.0000
207	K	A	-2.9898
208	P	A	-1.7528
209	S	A	-2.0366
210	N	A	-2.5754
211	T	A	-2.2846
212	K	A	-2.8563
213	V	A	-1.5135
214	D	A	-2.1699
215	K	A	-2.0156
216	K	A	-2.5109
217	V	A	0.0000
218	E	A	-2.7859
219	P	A	-1.8528
220	K	A	-2.1964