Project name: 5i5k:H

Chain sequence(s)	H: QVQLVQSGAEVKKPGASVKVSCKASGYIFSNYWIQWVRQAPGQGLEWMGEILPGSGSTEYTENFKDRVTMTRDTSTSTVYMELSSLRSEDTAVYYCARYFFGSSPNWYFDVWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVE
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.7649
• Maximal score value: 2.7812
• Average score: -0.5213
• Total score value: -115.2025

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-0.9378
2	V	H	-0.2012
3	Q	H	-0.8206
4	L	H	0.0000
5	V	H	0.2152
6	Q	H	-0.2993
7	S	H	-0.3942
8	G	H	-0.4454
9	A	H	0.2491
10	E	H	-0.4247
11	V	H	-0.1630
12	K	H	-1.8583
13	K	H	-2.5032
14	P	H	-2.4510
15	G	H	-1.8086
16	A	H	-1.4801
17	S	H	-1.7092
18	V	H	0.0000
19	K	H	-1.8781
20	V	H	0.0000
21	S	H	-0.5813
22	C	H	0.0000
23	K	H	-0.5166
24	A	H	0.0000
25	S	H	-0.2686
26	G	H	-0.4480
27	Y	H	0.6341
28	I	H	1.6439
29	F	H	0.5953
30	S	H	-0.4210
31	N	H	-0.5636
32	Y	H	0.6936
33	W	H	0.4895
34	I	H	0.0000
35	Q	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.2982
39	Q	H	-0.3142
40	A	H	-0.9900
41	P	H	-0.7488
42	G	H	-1.1305
43	Q	H	-1.5961
44	G	H	-0.8823
45	L	H	0.1346
46	E	H	-0.9497
47	W	H	-0.0621
48	M	H	0.0000
49	G	H	0.0000
50	E	H	-0.6452
51	I	H	0.0000
52	L	H	-0.6238
53	P	H	0.0000
54	G	H	-1.2150
55	S	H	-0.8359
56	G	H	-0.8254
57	S	H	-0.8356
58	T	H	-0.9958
59	E	H	-2.1751
60	Y	H	-2.0107
61	T	H	-2.3384
62	E	H	-3.4914
63	N	H	-2.8525
64	F	H	-2.4515
65	K	H	-3.7649
66	D	H	-3.4955
67	R	H	-3.2405
68	V	H	-1.8650
69	T	H	-1.1645
70	M	H	0.0000
71	T	H	-1.0524
72	R	H	-2.2065
73	D	H	-1.6555
74	T	H	-1.0047
75	S	H	-0.6659
76	T	H	-0.6656
77	S	H	-0.6077
78	T	H	0.0000
79	V	H	0.0000
80	Y	H	-0.7613
81	M	H	0.0000
82	E	H	-1.6966
83	L	H	0.0000
84	S	H	-1.7834
85	S	H	-1.6516
86	L	H	0.0000
87	R	H	-3.2665
88	S	H	-2.4834
89	E	H	-2.6588
90	D	H	-2.0092
91	T	H	-1.0512
92	A	H	0.0000
93	V	H	0.8628
94	Y	H	0.0000
95	Y	H	0.1510
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.0000
99	Y	H	1.8457
100	F	H	2.3355
101	F	H	2.7812
102	G	H	1.2324
103	S	H	0.1615
104	S	H	-0.1504
105	P	H	0.0185
106	N	H	0.5548
107	W	H	2.2494
108	Y	H	2.3452
109	F	H	1.8242
110	D	H	0.7358
111	V	H	0.5164
112	W	H	0.4901
113	G	H	-0.2631
114	Q	H	-0.7654
115	G	H	-0.0650
116	T	H	0.0000
117	L	H	1.4040
118	V	H	0.0000
119	T	H	-0.5149
120	V	H	-1.3864
121	S	H	-1.1224
122	S	H	-0.6377
123	A	H	-0.5138
124	S	H	-0.6987
125	T	H	-0.8727
126	K	H	-1.4167
127	G	H	-1.4757
128	P	H	0.0000
129	S	H	-0.0847
130	V	H	0.5356
131	F	H	1.8767
132	P	H	0.4374
133	L	H	0.7781
134	A	H	-0.2185
135	P	H	-0.6585
136	S	H	-0.8389
137	S	H	-1.2674
138	K	H	-2.0700
139	S	H	-1.3001
140	T	H	-1.1227
141	S	H	-1.0461
142	G	H	-1.1152
143	G	H	-0.9307
144	T	H	-0.6739
145	A	H	0.0000
146	A	H	0.0465
147	L	H	0.0000
148	G	H	0.0000
149	C	H	0.0000
150	L	H	0.8661
151	V	H	0.0000
152	K	H	-0.0202
153	D	H	-0.6637
154	Y	H	0.0000
155	F	H	0.0000
156	P	H	-1.0985
157	E	H	-1.7258
158	P	H	-1.3429
159	V	H	-0.9116
160	T	H	-0.6362
161	V	H	-0.3513
162	S	H	-0.3723
163	W	H	0.0000
164	N	H	-0.6287
165	S	H	-0.5226
166	G	H	-0.5839
167	A	H	-0.2616
168	L	H	-0.0216
169	T	H	-0.3003
170	S	H	-0.3825
171	G	H	-0.5215
172	V	H	-0.2150
173	H	H	-0.5010
174	T	H	0.4326
175	F	H	1.4568
176	P	H	0.8949
177	A	H	1.2078
178	V	H	2.5304
179	L	H	2.0676
180	Q	H	0.4822
181	S	H	-0.1628
182	S	H	-0.2293
183	G	H	0.0000
184	L	H	0.0000
185	Y	H	0.6654
186	S	H	0.6929
187	L	H	0.0000
188	S	H	0.6556
189	S	H	0.0000
190	V	H	0.4545
191	V	H	0.0000
192	T	H	-0.1971
193	V	H	0.0000
194	P	H	-0.7499
195	S	H	-0.8199
196	S	H	-0.8428
197	S	H	-0.7975
198	L	H	0.0000
199	G	H	-1.3163
200	T	H	-1.2402
201	Q	H	-1.6521
202	T	H	-1.3627
203	Y	H	0.0000
204	I	H	-1.2596
205	C	H	0.0000
206	N	H	-1.4222
207	V	H	0.0000
208	N	H	-1.7314
209	H	H	0.0000
210	K	H	-2.7835
211	P	H	-1.8046
212	S	H	-1.9903
213	N	H	-2.5082
214	T	H	-2.0277
215	K	H	-2.5759
216	V	H	-1.1968
217	D	H	-2.2240
218	K	H	0.0000
219	R	H	-2.6107
220	V	H	0.0000
221	E	H	-2.4784