Project name: 7da6e8b70f581ef

Chain sequence(s)	A: MDIVISGTRRVIYKSDQKSVVNVRLENKGNNPLLVQSWLDTGDTVPFTATTPPVSRIDAKRGQTIKLMYTASTSLPKDRESVFWFNVLEVPPLLQLAFRTRIKLFYRPDGLKGNPSSEAPLALKWFWSGSKASLRVTNPTPYYVSFSSGDLEASGKRYPIDVKMIAPFSDEVMKVNGLNGKANSAKVHFYAINDFGGAIEGNARL
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.17
• Maximal score value: 2.0277
• Average score: -0.8302
• Total score value: -166.8724

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	0.3874
2	D	A	-1.3874
3	I	A	0.0000
4	V	A	-0.1111
5	I	A	-0.2931
6	S	A	-0.5676
7	G	A	-0.3606
8	T	A	-0.2814
9	R	A	-0.2280
10	V	A	0.0000
11	I	A	0.1072
12	Y	A	0.0000
13	K	A	-2.4823
14	S	A	-2.7547
15	D	A	-3.3481
16	Q	A	-2.9264
17	K	A	-2.5357
18	S	A	-1.7016
19	V	A	-1.0442
20	N	A	-1.3835
21	V	A	0.0000
22	R	A	-1.3971
23	L	A	0.0000
24	E	A	-2.2354
25	N	A	0.0000
26	K	A	-3.4378
27	G	A	-2.8846
28	N	A	-2.9697
29	N	A	-2.8398
30	P	A	-2.6175
31	L	A	0.0000
32	L	A	-0.1773
33	V	A	0.0000
34	Q	A	0.0296
35	S	A	0.0000
36	W	A	0.2952
37	L	A	0.0000
38	D	A	-0.6038
39	T	A	-0.6409
40	G	A	-1.1808
41	D	A	-1.9051
50	T	A	-0.0216
51	V	A	0.1986
52	P	A	0.0000
53	F	A	0.0000
54	T	A	-0.0127
55	A	A	0.0000
56	T	A	-0.3001
57	P	A	-0.1096
58	P	A	0.3572
59	V	A	1.1630
60	S	A	-0.3226
61	R	A	-1.9350
62	I	A	0.0000
63	D	A	-3.3748
64	A	A	-3.7216
65	K	A	-4.1700
66	R	A	-3.8017
67	G	A	-2.4945
68	Q	A	-1.5318
69	T	A	-1.0890
70	I	A	0.0000
71	K	A	-1.4569
72	L	A	0.0000
73	M	A	-0.5366
74	Y	A	-0.3893
75	T	A	-0.1169
76	A	A	-0.0144
77	S	A	-0.1941
78	T	A	-0.1837
79	S	A	-0.4827
80	L	A	0.0000
81	P	A	-1.6416
82	K	A	-3.0318
83	D	A	-3.0915
84	R	A	-2.1613
85	E	A	0.0000
86	S	A	-0.4516
87	V	A	0.1485
88	F	A	0.0000
89	W	A	-0.4573
90	F	A	0.0000
91	N	A	0.0000
92	V	A	0.0000
93	L	A	0.2796
94	E	A	0.0000
95	V	A	0.3782
96	P	A	-0.2223
97	P	A	-0.6831
109	L	A	2.0245
110	L	A	2.0277
111	Q	A	0.6754
112	L	A	1.5847
113	A	A	1.1180
114	F	A	1.1522
115	R	A	-0.5040
116	T	A	-0.4022
117	R	A	-1.1649
118	I	A	-0.5256
119	K	A	-0.4433
120	L	A	0.0000
121	F	A	0.0000
122	Y	A	0.0000
123	R	A	-1.8178
124	P	A	0.0000
125	D	A	-3.5070
126	G	A	-2.3907
127	L	A	-2.4788
128	K	A	-2.7170
129	G	A	-2.3345
130	N	A	-2.5453
131	P	A	-1.5360
132	S	A	-1.2652
133	E	A	-1.9033
134	A	A	0.0000
135	P	A	0.0000
136	L	A	0.2711
137	A	A	-0.0721
138	L	A	0.0000
139	K	A	-1.5516
140	W	A	0.0000
141	F	A	0.2318
142	W	A	0.0406
143	S	A	-0.7241
144	G	A	-1.2194
145	S	A	-1.4957
148	K	A	-3.0006
149	A	A	0.0000
150	S	A	0.0000
151	L	A	0.0000
152	R	A	-1.0607
153	V	A	0.0000
154	T	A	-1.2037
155	N	A	0.0000
156	P	A	-0.3142
157	T	A	-0.7723
158	P	A	0.0000
159	Y	A	0.0000
160	Y	A	0.2704
161	V	A	0.0000
162	S	A	0.0000
163	F	A	-0.1448
164	S	A	-0.1852
165	S	A	-0.6920
166	G	A	0.0000
167	D	A	-1.5546
168	L	A	0.0000
169	E	A	-2.4110
170	A	A	0.0000
171	S	A	-1.6087
172	G	A	-1.9094
173	K	A	-2.9335
174	R	A	-3.2788
175	Y	A	-2.3007
176	P	A	-1.8841
177	I	A	0.0000
178	D	A	-2.6108
179	V	A	-1.2406
180	K	A	-1.3010
181	M	A	-0.1773
182	I	A	0.0000
183	A	A	-0.2159
184	P	A	0.0000
185	F	A	0.3740
186	S	A	-0.6214
187	D	A	-2.0261
188	E	A	-1.2257
189	V	A	-0.4786
190	M	A	0.0000
191	K	A	-2.5568
192	V	A	0.0000
193	N	A	-2.8900
194	G	A	-1.9706
195	L	A	-2.3426
196	N	A	-2.5256
197	G	A	-2.3300
198	K	A	-2.5449
199	A	A	-1.7167
200	N	A	-1.8247
201	S	A	-1.4524
202	A	A	0.0000
203	K	A	-2.0526
204	V	A	0.0000
205	H	A	-1.7411
206	F	A	0.0000
207	Y	A	-0.2597
208	A	A	0.0000
209	I	A	0.2741
210	N	A	0.1117
211	D	A	0.3895
212	F	A	1.4786
213	G	A	0.3928
214	G	A	0.1884
215	A	A	-0.0459
216	I	A	-0.5618
217	E	A	-1.4982
218	G	A	0.0000
219	N	A	-1.8503
220	A	A	-1.5217
221	R	A	-2.2018
222	L	A	-0.8892