Project name: mab4

Chain sequence(s)	H: EVQLVQSGAEVKKPGSSVKVSCKASGGTFSTYGISWVRQAPGQGLEWIGGIIPIFDTGNSAQSFQGRVTITADESTSTAYMEVSSLRSQQTAVYYCASSSRIYDYAGGDHYYYDMQVWGQGTMVTVS; L: AVLTQPSSVSTPPGQKVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAWVFGGGTKLTVLRT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.979
• Maximal score value: 2.1642
• Average score: -0.5548
• Total score value: -132.0471

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.4748
2	V	H	-0.0344
3	Q	H	-1.1719
4	L	H	0.0000
5	V	H	-0.4987
6	Q	H	0.0000
7	S	H	-0.8526
8	G	H	-0.7665
9	A	H	-0.1842
10	E	H	-0.5952
11	V	H	0.6481
12	K	H	-1.0907
13	K	H	-2.1366
14	P	H	-2.0303
15	G	H	-1.5966
16	S	H	-1.2671
17	S	H	-1.5774
18	V	H	0.0000
19	K	H	-2.1272
20	V	H	0.0000
21	S	H	-0.7673
22	C	H	0.0000
23	K	H	-1.7383
24	A	H	0.0000
25	S	H	-1.1013
26	G	H	-1.1590
27	G	H	-1.0488
28	T	H	-0.8647
29	F	H	0.0000
30	S	H	0.2354
31	T	H	1.1449
32	Y	H	1.0842
33	G	H	0.0000
34	I	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.6942
40	A	H	0.0000
41	P	H	-1.0291
42	G	H	-1.2666
43	Q	H	-1.7847
44	G	H	-0.9695
45	L	H	0.0000
46	E	H	-0.7885
47	W	H	0.0000
48	I	H	0.0000
49	G	H	0.0000
50	G	H	0.0000
51	I	H	0.0000
52	I	H	0.0000
52A	P	H	-0.3905
53	I	H	0.7697
54	F	H	0.5695
55	D	H	-1.4063
56	T	H	-0.7493
57	G	H	-0.9885
58	N	H	-0.9727
59	S	H	-1.2292
60	A	H	-0.9495
61	Q	H	-1.6368
62	S	H	-1.4003
63	F	H	0.0000
64	Q	H	-2.4646
65	G	H	-2.1181
66	R	H	-2.5744
67	V	H	-1.6830
68	T	H	-1.0932
69	I	H	-0.4292
70	T	H	-0.6478
71	A	H	-0.9827
72	D	H	-1.6173
73	E	H	-1.5646
74	S	H	-1.0110
75	T	H	-1.1281
76	S	H	0.0000
77	T	H	0.0000
78	A	H	0.0000
79	Y	H	-0.6033
80	M	H	0.0000
81	E	H	-1.7394
82	V	H	0.0000
82A	S	H	-1.5998
82B	S	H	-1.4796
82C	L	H	0.0000
83	R	H	-2.9405
84	S	H	-2.1639
85	Q	H	-2.0575
86	Q	H	-1.4260
87	T	H	-0.6404
88	A	H	0.0000
89	V	H	0.2859
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	A	H	0.0000
94	S	H	0.0000
95	S	H	0.0000
96	S	H	0.5356
97	R	H	0.0000
98	I	H	2.1642
99	Y	H	1.6846
100	D	H	-0.4332
100A	Y	H	0.2951
100B	A	H	-0.2509
100C	G	H	-0.8370
100D	G	H	-0.6331
100E	D	H	-0.4568
100F	H	H	-0.3109
100G	Y	H	0.3380
100H	Y	H	0.6198
100I	Y	H	0.2222
100J	D	H	-0.0021
100K	M	H	0.0000
101	Q	H	-0.4223
102	V	H	-0.0716
103	W	H	-0.2524
104	G	H	0.0000
105	Q	H	-1.2020
106	G	H	-0.4780
107	T	H	0.0000
108	M	H	0.2991
109	V	H	0.0000
110	T	H	-0.3109
111	V	H	0.0000
112	S	H	-1.0987
2	A	L	0.2764
3	V	L	1.3570
4	L	L	0.0000
5	T	L	-0.0474
6	Q	L	-0.5305
7	P	L	-0.6681
8	S	L	-0.9042
10	S	L	-0.9737
11	V	L	-0.3831
12	S	L	-0.5119
13	T	L	0.0000
14	P	L	-1.1020
15	P	L	-1.5752
16	G	L	-1.7717
17	Q	L	-2.3591
18	K	L	-2.4700
19	V	L	0.0000
20	T	L	-0.4926
21	I	L	0.0000
22	S	L	-0.3753
23	C	L	0.0000
24	S	L	-0.2967
25	G	L	-0.2422
26	S	L	-0.5976
27	S	L	-0.9577
28	S	L	-0.5438
29	N	L	0.0000
30	I	L	0.0000
30A	G	L	-1.1530
30B	N	L	-1.2880
31	N	L	0.0000
32	Y	L	0.5814
33	V	L	0.0000
34	S	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	0.0000
38	Q	L	-0.7223
39	L	L	-0.2379
40	P	L	-0.4209
41	G	L	-0.5833
42	T	L	-0.6200
43	A	L	-0.5812
44	P	L	0.0000
45	K	L	-1.0956
46	L	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	-1.0277
50	D	L	-1.7057
51	N	L	-1.5104
52	N	L	-2.5356
53	K	L	-2.9790
54	R	L	-1.9898
55	P	L	-0.9406
56	S	L	-0.6011
57	G	L	-0.7482
58	I	L	-0.9316
59	P	L	-1.2736
60	D	L	-2.3306
61	R	L	-1.6574
62	F	L	0.0000
63	S	L	-1.3970
64	G	L	0.0000
65	S	L	-1.2179
66	K	L	-0.9240
67	S	L	-0.8028
68	G	L	-1.0770
69	T	L	-0.9842
70	S	L	-0.7356
71	A	L	0.0000
72	T	L	-0.5764
73	L	L	0.0000
74	G	L	-0.6066
75	I	L	0.0000
76	T	L	-1.8150
77	G	L	-1.7444
78	L	L	0.0000
79	Q	L	-1.7952
80	T	L	-1.2299
81	G	L	-1.0641
82	D	L	0.0000
83	E	L	-1.4989
84	A	L	0.0000
85	D	L	-1.2407
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	G	L	0.0000
90	T	L	0.0000
91	W	L	0.5050
92	D	L	0.0000
93	S	L	0.0216
94	S	L	0.4175
95	L	L	1.2195
95A	S	L	0.5717
95B	A	L	0.4390
96	W	L	0.0000
97	V	L	0.0000
98	F	L	0.0000
99	G	L	0.0000
100	G	L	-0.7416
101	G	L	-1.0696
102	T	L	0.0000
103	K	L	-2.1369
104	L	L	0.0000
105	T	L	-0.7274
106	V	L	0.0000
107	L	L	0.0370
108	R	L	-1.4167
109	T	L	-0.7677