Project name: Kari & Erin 1E

Chain sequence(s)	A: HPQMQGGTMRNTLLNMLATLMWVLTACAEVVPVQNFDLEKMTGKWFTAGFASNAQWFVNHKASMKMGTATLTPTEGGDIDLSYTTLNADGSCWRMTHLAKKTDTPGRFTFHSQVWNNDNDMRIVDAVYDEYALVHTVKTKEGVSQVLNKLYTRSPEASDDLKQKFTQFSLDTGILSDNIAFFPRNGFRVSQHHK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.202
• Maximal score value: 1.3198
• Average score: -0.7008
• Total score value: -135.948

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	H	A	-2.1284
2	P	A	-1.7242
3	Q	A	-1.6092
4	M	A	-0.4209
5	Q	A	-1.8416
6	G	A	-2.0080
7	G	A	-1.9516
8	T	A	-1.0673
9	M	A	-0.4315
10	R	A	-1.9699
11	N	A	-1.8693
12	T	A	-0.9900
13	L	A	0.0000
14	L	A	0.0000
15	N	A	-0.1868
16	M	A	-0.1765
17	L	A	0.0000
18	A	A	0.0000
19	T	A	0.0000
20	L	A	0.0942
21	M	A	0.4498
22	W	A	1.1612
23	V	A	1.0535
24	L	A	0.6385
25	T	A	0.0000
26	A	A	0.3210
27	C	A	-0.0390
28	A	A	-0.5616
29	E	A	-1.7752
30	V	A	0.0000
31	V	A	0.5090
32	P	A	-0.4152
33	V	A	-0.6112
34	Q	A	-1.6160
35	N	A	-1.9149
36	F	A	-1.4992
37	D	A	-2.0445
38	L	A	0.0000
39	E	A	-2.8291
40	K	A	-2.7912
41	M	A	0.0000
42	T	A	-1.4718
43	G	A	-1.3162
44	K	A	-1.0314
45	W	A	0.0000
46	F	A	-0.1417
47	T	A	0.0000
48	A	A	0.0000
49	G	A	0.0000
50	F	A	0.0000
51	A	A	0.0000
52	S	A	0.0000
53	N	A	0.2185
54	A	A	0.7890
55	Q	A	0.0328
56	W	A	0.9215
57	F	A	1.1529
58	V	A	0.0000
59	N	A	-1.9540
60	H	A	-1.8236
61	K	A	-2.4120
62	A	A	-0.7798
63	S	A	-0.5421
64	M	A	-0.3921
65	K	A	-1.0540
66	M	A	0.0000
67	G	A	0.0000
68	T	A	0.0000
69	A	A	0.0000
70	T	A	-0.5015
71	L	A	-0.6314
72	T	A	-0.7687
73	P	A	-1.3695
74	T	A	-1.4352
75	E	A	-2.1741
76	G	A	-1.6771
77	G	A	-1.5997
78	D	A	-1.3142
79	I	A	0.0000
80	D	A	-0.4429
81	L	A	0.0000
82	S	A	-0.3612
83	Y	A	0.0000
84	T	A	0.0000
85	T	A	0.0000
86	L	A	-0.4968
87	N	A	-0.7520
88	A	A	-1.2378
89	D	A	-2.2294
90	G	A	-1.2787
91	S	A	-0.6210
92	C	A	-0.0787
93	W	A	0.4919
94	R	A	-0.3065
95	M	A	0.0098
96	T	A	-0.0720
97	H	A	-0.1061
98	L	A	-0.1457
99	A	A	0.0000
100	K	A	-1.5545
101	K	A	-1.9385
102	T	A	-1.7797
103	D	A	-2.2521
104	T	A	-1.4378
105	P	A	-1.4746
106	G	A	0.0000
107	R	A	-1.3893
108	F	A	0.0000
109	T	A	-0.9095
110	F	A	-0.9789
111	H	A	-1.3596
112	S	A	-0.6330
113	Q	A	-0.7765
114	V	A	1.3198
115	W	A	1.0883
116	N	A	-1.0381
117	N	A	-2.0741
118	D	A	-1.9334
119	N	A	-0.9427
120	D	A	0.0000
121	M	A	0.0000
122	R	A	-0.6281
123	I	A	0.0000
124	V	A	0.0000
125	D	A	0.0204
126	A	A	0.0000
127	V	A	-0.0474
128	Y	A	-1.1249
129	D	A	-2.6092
130	E	A	-2.4978
131	Y	A	-1.0077
132	A	A	0.0000
133	L	A	0.0000
134	V	A	0.0000
135	H	A	0.0000
136	T	A	0.0000
137	V	A	0.0000
138	K	A	0.0000
139	T	A	-1.2837
140	K	A	-1.4832
141	E	A	-2.5144
142	G	A	-1.3748
143	V	A	-0.0053
144	S	A	0.0000
145	Q	A	0.0000
146	V	A	0.0000
147	L	A	0.0000
148	N	A	0.0000
149	K	A	0.0000
150	L	A	0.0000
151	Y	A	0.0000
152	T	A	0.0000
153	R	A	-1.9036
154	S	A	-1.4864
155	P	A	-1.1409
156	E	A	-1.7247
157	A	A	-1.6397
158	S	A	-2.2016
159	D	A	-3.2018
160	D	A	-3.2020
161	L	A	-2.3152
162	K	A	-2.1118
163	Q	A	-2.7919
164	K	A	-2.2296
165	F	A	0.0000
166	T	A	-0.9058
167	Q	A	-1.5843
168	F	A	0.0000
169	S	A	0.0000
170	L	A	1.0103
171	D	A	-0.5887
172	T	A	0.0000
173	G	A	0.6779
174	I	A	0.0000
175	L	A	1.1778
176	S	A	-0.0253
177	D	A	-1.4173
178	N	A	0.0000
179	I	A	0.2394
180	A	A	0.2347
181	F	A	0.8060
182	F	A	0.0000
183	P	A	-1.2585
184	R	A	-2.5363
185	N	A	-2.3157
186	G	A	-1.4904
187	F	A	-0.6821
188	R	A	-0.4864
189	V	A	0.0647
190	S	A	-0.6374
191	Q	A	-0.9872
192	H	A	-1.4270
193	H	A	-1.8656
194	K	A	-2.2337