Project name: 3wd5:L
Status: done
submitted: 2019-03-20 20:14:07, status changed: 2019-03-20 20:23:30
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCRASQGIRNYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISSLQPEDVATYYCQRYNRAPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.5241
-
Maximal score value
-
1.464
-
Average score
-
-0.8926
-
Total score value
-
-190.1324
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-2.2751 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-2.1755 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-1.3557 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.7719 |
|
| 8 |
P |
L |
-0.7082 |
|
| 9 |
S |
L |
-1.0153 |
|
| 10 |
S |
L |
-1.1001 |
|
| 11 |
L |
L |
-0.7143 |
|
| 12 |
S |
L |
-1.0052 |
|
| 13 |
A |
L |
-1.3284 |
|
| 14 |
S |
L |
-1.4246 |
|
| 15 |
V |
L |
-0.7737 |
|
| 16 |
G |
L |
-1.2541 |
|
| 17 |
D |
L |
-2.2093 |
|
| 18 |
R |
L |
-2.5079 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.4969 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.8790 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.9117 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-2.1011 |
|
| 27 |
Q |
L |
-2.5484 |
|
| 28 |
G |
L |
-2.1772 |
|
| 29 |
I |
L |
0.0000 |
|
| 30 |
R |
L |
-2.4792 |
|
| 31 |
N |
L |
-1.3432 |
|
| 32 |
Y |
L |
-0.5752 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
A |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.0479 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.5960 |
|
| 39 |
K |
L |
-2.1829 |
|
| 40 |
P |
L |
-1.6938 |
|
| 41 |
G |
L |
-1.7315 |
|
| 42 |
K |
L |
-2.4229 |
|
| 43 |
A |
L |
-1.5305 |
|
| 44 |
P |
L |
-1.5425 |
|
| 45 |
K |
L |
-1.8957 |
|
| 46 |
L |
L |
-0.4018 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
0.7504 |
|
| 50 |
A |
L |
0.0550 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-0.1835 |
|
| 53 |
T |
L |
0.0924 |
|
| 54 |
L |
L |
0.0298 |
|
| 55 |
Q |
L |
-0.6087 |
|
| 56 |
S |
L |
-0.6155 |
|
| 57 |
G |
L |
-0.7122 |
|
| 58 |
V |
L |
0.0000 |
|
| 59 |
P |
L |
-0.5295 |
|
| 60 |
S |
L |
-0.5756 |
|
| 61 |
R |
L |
-0.8279 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.2937 |
|
| 64 |
G |
L |
0.0000 |
|
| 65 |
S |
L |
-0.6609 |
|
| 66 |
G |
L |
-1.3634 |
|
| 67 |
S |
L |
-1.5065 |
|
| 68 |
G |
L |
-2.0646 |
|
| 69 |
T |
L |
-2.3068 |
|
| 70 |
D |
L |
-2.6293 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7410 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.5735 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.4268 |
|
| 77 |
S |
L |
-1.3719 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-1.3401 |
|
| 80 |
P |
L |
-1.9470 |
|
| 81 |
E |
L |
-2.2838 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
V |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
-1.1907 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.0975 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.7767 |
|
| 90 |
R |
L |
-0.0458 |
|
| 91 |
Y |
L |
0.0328 |
|
| 92 |
N |
L |
-1.3552 |
|
| 93 |
R |
L |
-1.7155 |
|
| 94 |
A |
L |
-0.5802 |
|
| 95 |
P |
L |
-0.2042 |
|
| 96 |
Y |
L |
1.0148 |
|
| 97 |
T |
L |
0.4140 |
|
| 98 |
F |
L |
1.0296 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
Q |
L |
-1.0751 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-2.0695 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-2.0402 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.9816 |
|
| 108 |
R |
L |
-1.1357 |
|
| 109 |
T |
L |
-0.2819 |
|
| 110 |
V |
L |
0.0974 |
|
| 111 |
A |
L |
-0.2056 |
|
| 112 |
A |
L |
-0.2618 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.0896 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.3865 |
|
| 117 |
I |
L |
1.2415 |
|
| 118 |
F |
L |
1.4640 |
|
| 119 |
P |
L |
-0.1713 |
|
| 120 |
P |
L |
-0.7174 |
|
| 121 |
S |
L |
-1.7701 |
|
| 122 |
D |
L |
-3.3159 |
|
| 123 |
E |
L |
-3.5241 |
|
| 124 |
Q |
L |
-2.5756 |
|
| 125 |
L |
L |
-2.2825 |
|
| 126 |
K |
L |
-3.1274 |
|
| 127 |
S |
L |
-2.0180 |
|
| 128 |
G |
L |
-1.5011 |
|
| 129 |
T |
L |
-1.1430 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
-0.1910 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.8894 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.5700 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.5375 |
|
| 138 |
N |
L |
-1.3079 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
-1.2476 |
|
| 141 |
P |
L |
-1.7457 |
|
| 142 |
R |
L |
-2.9043 |
|
| 143 |
E |
L |
-3.1698 |
|
| 144 |
A |
L |
-2.2144 |
|
| 145 |
K |
L |
-2.1752 |
|
| 146 |
V |
L |
-1.0803 |
|
| 147 |
Q |
L |
-0.4972 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.5784 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.9863 |
|
| 152 |
N |
L |
-1.5487 |
|
| 153 |
A |
L |
-0.3621 |
|
| 154 |
L |
L |
0.5957 |
|
| 155 |
Q |
L |
-0.4608 |
|
| 156 |
S |
L |
-0.6199 |
|
| 157 |
G |
L |
-1.2999 |
|
| 158 |
N |
L |
-1.9419 |
|
| 159 |
S |
L |
-1.9168 |
|
| 160 |
Q |
L |
-2.4696 |
|
| 161 |
E |
L |
-2.5518 |
|
| 162 |
S |
L |
-1.4027 |
|
| 163 |
V |
L |
-0.8735 |
|
| 164 |
T |
L |
-1.3312 |
|
| 165 |
E |
L |
-2.4974 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.6764 |
|
| 168 |
S |
L |
-2.6326 |
|
| 169 |
K |
L |
-2.7687 |
|
| 170 |
D |
L |
-2.1157 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-1.0288 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.5578 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.8396 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.8912 |
|
| 181 |
L |
L |
0.0000 |
|
| 182 |
S |
L |
-1.0571 |
|
| 183 |
K |
L |
-2.0000 |
|
| 184 |
A |
L |
-1.6888 |
|
| 185 |
D |
L |
-2.1738 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.4776 |
|
| 188 |
K |
L |
-3.2535 |
|
| 189 |
H |
L |
-2.7225 |
|
| 190 |
K |
L |
-2.6272 |
|
| 191 |
V |
L |
-1.2979 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.7504 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.0579 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.7706 |
|
| 200 |
G |
L |
-0.4822 |
|
| 201 |
L |
L |
-0.3199 |
|
| 202 |
S |
L |
-0.4770 |
|
| 203 |
S |
L |
-0.4192 |
|
| 204 |
P |
L |
-0.5074 |
|
| 205 |
V |
L |
-0.0262 |
|
| 206 |
T |
L |
-0.3352 |
|
| 207 |
K |
L |
-0.3693 |
|
| 208 |
S |
L |
-0.5951 |
|
| 209 |
F |
L |
-0.7607 |
|
| 210 |
N |
L |
-1.7775 |
|
| 211 |
R |
L |
-2.0181 |
|
| 212 |
G |
L |
-1.8623 |
|
| 213 |
E |
L |
-2.3019 |
|