Project name: 8103eccd15fdc64

Chain sequence(s)	C: QSQLDRERILSLEQRVVELQQTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVETS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.8985
• Maximal score value: 1.832
• Average score: -0.9434
• Total score value: -183.9571

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
221	Q	C	-2.0294
222	S	C	-2.1297
223	Q	C	-2.5645
224	L	C	-1.6840
225	D	C	-3.2956
226	R	C	-3.3319
227	E	C	-3.2497
228	R	C	-2.7602
229	I	C	-1.0003
230	L	C	-0.4249
231	S	C	-1.2808
232	L	C	-0.9087
233	E	C	-1.3530
234	Q	C	-1.5540
235	R	C	-1.5111
236	V	C	0.3933
237	V	C	0.1804
238	E	C	-1.4713
239	L	C	0.1052
240	Q	C	-0.5504
241	Q	C	-1.5186
242	T	C	-1.1046
243	L	C	-0.5480
244	A	C	-1.6533
245	Q	C	-2.6855
246	K	C	-3.0016
247	D	C	-2.8984
248	Q	C	-2.8063
249	A	C	-1.7338
250	L	C	-0.9332
251	G	C	-1.9573
252	K	C	-2.3505
253	L	C	-0.4438
254	E	C	-1.9313
255	Q	C	-2.2135
256	S	C	-1.1208
257	L	C	-0.9523
258	R	C	-2.7397
259	L	C	-1.2047
260	M	C	-0.6018
261	E	C	-2.5552
262	E	C	-2.3930
263	A	C	-0.9856
264	S	C	-0.6935
265	F	C	-0.4433
266	D	C	-1.8394
267	G	C	0.0000
268	T	C	-0.2785
269	F	C	0.0000
270	L	C	0.5797
271	W	C	0.0000
272	K	C	-1.3400
273	I	C	0.0000
274	T	C	-1.8876
275	N	C	-2.4736
276	V	C	0.0000
277	T	C	-1.9692
278	R	C	-3.1306
279	R	C	-2.5077
280	C	C	-1.6725
281	H	C	-2.1859
282	E	C	-1.8571
283	S	C	0.0000
284	A	C	-1.0395
285	C	C	-0.2612
286	G	C	-0.6301
287	R	C	-1.7353
288	T	C	-0.4264
289	V	C	1.0080
290	S	C	0.6813
291	L	C	1.2311
292	F	C	1.8320
293	S	C	0.0000
294	P	C	-0.2321
295	A	C	0.2840
296	F	C	0.0000
297	Y	C	-0.1965
298	T	C	0.0000
299	A	C	-0.6651
300	K	C	-1.0832
301	Y	C	0.6255
302	G	C	0.0708
303	Y	C	0.0000
304	K	C	-0.8375
305	L	C	0.0000
306	C	C	0.0000
307	L	C	0.0000
308	R	C	0.3093
309	L	C	0.0000
310	Y	C	0.0000
311	L	C	0.0000
312	N	C	-1.4020
313	G	C	0.0000
314	D	C	-1.6510
315	G	C	-1.4960
316	T	C	-1.0333
317	G	C	0.0000
318	K	C	-2.7196
319	R	C	-2.7021
320	T	C	-1.4272
321	H	C	-1.0687
322	L	C	0.0000
323	S	C	0.0000
324	L	C	0.0000
325	F	C	0.0000
326	I	C	0.0000
327	V	C	0.0000
328	I	C	0.0000
329	M	C	-1.9028
330	R	C	-3.4679
331	G	C	0.0000
332	E	C	-1.6661
333	Y	C	-0.0506
334	D	C	0.0000
335	A	C	0.3380
336	L	C	1.7482
337	L	C	1.0010
338	P	C	-0.1232
339	W	C	-0.3513
340	P	C	-0.8973
341	F	C	0.0000
342	R	C	-2.1400
343	N	C	-2.0223
344	K	C	-2.1918
345	V	C	0.0000
346	T	C	0.0000
347	F	C	0.0000
348	M	C	0.7631
349	L	C	0.0000
350	L	C	-0.4145
351	D	C	0.0000
352	Q	C	-2.0040
353	N	C	-2.5464
354	N	C	-3.0953
355	R	C	-3.8985
356	E	C	-3.2815
357	H	C	-1.4187
358	A	C	0.0574
359	I	C	1.2706
360	D	C	0.1631
361	A	C	-0.2318
362	F	C	-1.3126
363	R	C	-2.7318
364	P	C	0.0000
365	D	C	-2.0572
366	L	C	-0.5185
367	S	C	-0.3797
368	S	C	-0.3147
369	A	C	-0.2875
370	S	C	0.0000
371	F	C	0.0000
372	Q	C	-1.8081
373	R	C	-2.4093
374	P	C	0.0000
375	Q	C	-2.5344
376	S	C	-2.2360
377	E	C	-2.8618
378	T	C	-1.5215
379	N	C	-0.5379
380	V	C	1.6844
381	A	C	0.7010
382	S	C	0.0412
383	G	C	-0.3612
384	C	C	0.0153
385	P	C	-0.2113
386	L	C	0.2282
387	F	C	0.0000
388	F	C	0.0000
389	P	C	-0.5437
390	L	C	-0.7722
391	S	C	-1.2084
392	K	C	-2.3290
393	L	C	0.0000
394	Q	C	-2.1011
395	S	C	-1.8598
396	P	C	-1.6342
397	K	C	-2.7562
398	H	C	0.0000
399	A	C	-1.9817
400	Y	C	0.0000
401	V	C	-1.3132
402	K	C	-2.3730
403	D	C	-2.7914
404	D	C	-2.4724
405	T	C	-1.8441
406	M	C	0.0000
407	F	C	-0.2637
408	L	C	0.0000
409	K	C	0.2288
410	C	C	0.0000
411	I	C	-0.2620
412	V	C	0.0000
413	E	C	-2.6191
414	T	C	-1.3635
415	S	C	-0.9038