Project name: 826eafb367cfd7a

Chain sequence(s)	A: ATQRFLIEKFSQEQIGENIVCRVICTTGQIPIRDLSADISQVLKEKRSIKKVWTFGRNPACDYHLGNISRLSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVEKNSNQLLSQGDEITVGVGVESDILSLVIFINDKFKQCLEQNKVDRIR; B: SLEVEADATFVQ
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.9423
• Maximal score value: 2.4955
• Average score: -0.9858
• Total score value: -160.682

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
14	A	A	-0.2029
15	T	A	-0.3770
16	Q	A	-1.2666
17	R	A	-1.6928
18	F	A	0.3145
19	L	A	0.6305
20	I	A	0.0213
21	E	A	-1.9533
22	K	A	-1.6240
23	F	A	0.5435
24	S	A	-1.2127
25	Q	A	-2.6386
26	E	A	-2.9331
27	Q	A	-2.1538
28	I	A	-0.0032
29	G	A	-1.2753
30	E	A	-2.2383
31	N	A	-1.5584
32	I	A	-1.2032
33	V	A	0.0000
34	C	A	0.0000
35	R	A	-0.7039
36	V	A	0.0000
37	I	A	0.2486
38	C	A	-0.0454
39	T	A	-0.1420
40	T	A	-0.3832
41	G	A	-0.7512
42	Q	A	-1.2577
43	I	A	0.0000
44	P	A	-0.1080
45	I	A	0.5705
46	R	A	-1.7242
47	D	A	-1.7066
48	L	A	0.0000
49	S	A	-1.2156
50	A	A	0.0000
51	D	A	-1.5945
52	I	A	-0.4346
53	S	A	-0.7675
54	Q	A	-1.5747
55	V	A	0.0000
56	L	A	-0.9089
57	K	A	-2.2605
58	E	A	0.0000
59	K	A	-3.1237
60	R	A	-2.8584
61	S	A	-1.8275
62	I	A	-1.1759
63	K	A	-1.5547
64	K	A	-0.6963
65	V	A	-0.0773
66	W	A	0.0000
67	T	A	-0.7004
68	F	A	0.0000
69	G	A	0.0000
70	R	A	-2.0551
71	N	A	-1.7476
72	P	A	-1.0567
73	A	A	-0.7778
74	C	A	0.0000
75	D	A	-1.2080
76	Y	A	0.0000
77	H	A	-1.9462
78	L	A	0.0000
79	G	A	-1.4525
80	N	A	-1.9084
81	I	A	-1.1135
82	S	A	-1.0695
83	R	A	-1.2579
84	L	A	0.0000
85	S	A	-1.1817
86	N	A	-1.8386
87	K	A	-1.8043
88	H	A	0.0000
89	F	A	0.0000
90	Q	A	-0.6236
91	I	A	0.0000
92	L	A	0.0000
93	L	A	0.0000
94	G	A	0.0000
95	E	A	-3.2112
96	D	A	-3.3252
97	G	A	-3.0845
98	N	A	-1.8291
99	L	A	0.0000
100	L	A	-0.2545
101	L	A	0.0000
102	N	A	0.0000
103	D	A	0.0000
104	I	A	-0.9360
105	S	A	0.0000
106	T	A	-0.7524
107	N	A	-1.0993
108	G	A	0.0000
109	T	A	0.0000
110	W	A	-1.6576
111	L	A	-1.6652
112	N	A	-2.2443
113	G	A	-2.0219
114	Q	A	-2.6655
115	K	A	-2.8840
116	V	A	-2.4646
117	E	A	-3.3357
118	K	A	-3.0706
119	N	A	-2.5664
120	S	A	-2.3636
121	N	A	-1.9122
122	Q	A	-0.6378
123	L	A	0.9393
124	L	A	0.3529
125	S	A	-0.1574
126	Q	A	-0.9267
127	G	A	-0.3925
128	D	A	0.0000
129	E	A	-1.0983
130	I	A	0.0000
131	T	A	-0.6277
132	V	A	0.0000
133	G	A	0.0000
134	V	A	-0.4463
135	G	A	-0.9685
136	V	A	-0.5408
137	E	A	-1.6908
138	S	A	-1.1586
139	D	A	-1.1220
140	I	A	-0.0404
141	L	A	0.0000
142	S	A	-0.3217
143	L	A	0.0000
144	V	A	-0.0518
145	I	A	0.0000
146	F	A	0.5713
147	I	A	0.0189
148	N	A	-1.3333
149	D	A	-2.6849
150	K	A	-3.1051
151	F	A	-2.5611
152	K	A	-3.5057
153	Q	A	-3.6041
154	C	A	-2.2923
155	L	A	-2.8820
156	E	A	-3.9423
157	Q	A	-3.0923
158	N	A	-3.0958
159	K	A	-2.6023
160	V	A	-0.6573
161	D	A	-2.3314
162	R	A	-1.9242
163	I	A	0.0581
164	R	A	-1.6140
165	S	B	0.3685
166	L	B	0.7404
167	E	B	-0.5362
168	V	B	0.6181
170	E	B	-2.0208
171	A	B	-1.5835
172	D	B	-2.2331
173	A	B	-0.1877
174	T	B	0.8637
175	F	B	2.4955
176	V	B	2.1206
177	Q	B	0.1236