Project name: 3eoa:H

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAASGYSFTGHWMNWVRQAPGKGLEWVGMIHPSDSETRYNQKFKDRFTISVDKSKNTLYLQMNSLRAEDTAVYYCARGIYFYGTTYFDYWGQGTLVTVSSASTKGPSVFPLAPSSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVE
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.833
• Maximal score value: 3.0836
• Average score: -0.5508
• Total score value: -118.4242

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.1563
2	V	H	-1.2461
3	Q	H	-1.1058
4	L	H	0.0000
5	V	H	1.2091
6	E	H	0.0000
7	S	H	-0.3969
8	G	H	-0.9030
9	G	H	-0.7240
10	G	H	-0.4025
11	L	H	-0.1342
12	V	H	0.0000
13	Q	H	-1.7223
14	P	H	-1.6463
15	G	H	-1.4624
16	G	H	-1.1572
17	S	H	-1.2002
18	L	H	-1.2508
19	R	H	-2.2173
20	L	H	0.0000
21	S	H	-0.3571
22	C	H	0.0000
23	A	H	-0.1365
24	A	H	0.0000
25	S	H	-0.9113
26	G	H	-1.3282
27	Y	H	-0.7720
28	S	H	-0.5167
29	F	H	0.0000
30	T	H	-1.1098
31	G	H	-0.6267
32	H	H	-0.2920
33	W	H	-0.1002
34	M	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.1751
39	Q	H	-0.5362
40	A	H	-1.1355
41	P	H	-1.2675
42	G	H	-1.5619
43	K	H	-2.0911
44	G	H	-0.9598
45	L	H	0.5727
46	E	H	-0.4365
47	W	H	0.0241
48	V	H	0.0000
49	G	H	0.0000
50	M	H	0.0000
51	I	H	0.0000
52	H	H	-1.4308
53	P	H	0.0000
54	S	H	-1.7036
55	D	H	-2.5328
56	S	H	-2.1423
57	E	H	-2.4989
58	T	H	-1.8714
59	R	H	-2.5053
60	Y	H	-2.0807
61	N	H	-2.3387
62	Q	H	-3.2657
63	K	H	-3.2044
64	F	H	0.0000
65	K	H	-3.8330
66	D	H	-3.4334
67	R	H	-2.3190
68	F	H	0.0000
69	T	H	-1.3067
70	I	H	0.0000
71	S	H	-0.5198
72	V	H	-1.1711
73	D	H	-1.7964
74	K	H	-2.7917
75	S	H	-2.0784
76	K	H	-2.7379
77	N	H	-2.3417
78	T	H	-1.2188
79	L	H	0.0000
80	Y	H	-0.5441
81	L	H	0.0000
82	Q	H	-1.5563
83	M	H	0.0000
84	N	H	-1.6429
85	S	H	-1.4484
86	L	H	0.0000
87	R	H	-2.5354
88	A	H	-1.8317
89	E	H	-2.2804
90	D	H	0.0000
91	T	H	-0.8542
92	A	H	0.0000
93	V	H	0.2705
94	Y	H	0.0000
95	Y	H	0.3064
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.2427
99	G	H	0.0000
100	I	H	0.0000
101	Y	H	2.4610
102	F	H	3.0836
103	Y	H	2.4756
104	G	H	0.9402
105	T	H	0.9332
106	T	H	1.4564
107	Y	H	1.7597
108	F	H	0.9595
109	D	H	0.0062
110	Y	H	0.2664
111	W	H	0.4034
112	G	H	0.0582
113	Q	H	-0.6893
114	G	H	-0.1721
115	T	H	-0.0423
116	L	H	0.0690
117	V	H	0.0000
118	T	H	0.0000
119	V	H	0.0000
120	S	H	-1.0316
121	S	H	-0.8968
122	A	H	-0.4830
123	S	H	-0.5953
124	T	H	-0.7716
125	K	H	-1.3975
126	G	H	-1.5174
127	P	H	-0.7303
128	S	H	-0.1143
129	V	H	0.4184
130	F	H	1.7707
131	P	H	0.5522
132	L	H	0.7562
133	A	H	-0.2344
134	P	H	-0.3134
135	S	H	-0.2806
136	S	H	-0.3162
142	G	H	-0.6328
143	T	H	-0.4948
144	A	H	0.0000
145	A	H	0.0819
146	L	H	0.0000
147	G	H	0.0000
148	C	H	0.0000
149	L	H	0.7952
150	V	H	0.0000
151	K	H	-0.8155
152	D	H	-1.0375
153	Y	H	0.0000
154	F	H	0.0000
155	P	H	0.0000
156	E	H	-0.6126
157	P	H	-0.6410
158	V	H	-0.6456
159	T	H	-0.5393
160	V	H	-0.1278
161	S	H	-0.4377
162	W	H	0.0000
163	N	H	-0.7447
164	S	H	-0.6786
165	G	H	-0.5826
166	A	H	-0.2380
167	L	H	0.0140
168	T	H	-0.2255
169	S	H	-0.3003
170	G	H	-0.3396
171	V	H	0.0854
172	H	H	-0.3375
173	T	H	0.1486
174	F	H	0.7995
175	P	H	0.6526
176	A	H	1.1423
177	V	H	2.5353
178	L	H	2.0685
179	Q	H	0.4865
180	S	H	-0.2453
181	S	H	-0.3395
182	G	H	-0.1279
183	L	H	0.0179
184	Y	H	0.5331
185	S	H	0.4157
186	L	H	0.0000
187	S	H	0.6198
188	S	H	0.0000
189	V	H	0.4565
190	V	H	0.0000
191	T	H	-0.1938
192	V	H	0.0000
193	P	H	-0.5519
194	S	H	-0.5273
195	S	H	-0.5538
196	S	H	-0.5220
197	L	H	-0.6041
198	G	H	-0.9219
199	T	H	-0.6851
200	Q	H	-1.2515
201	T	H	-0.9951
202	Y	H	0.0000
203	I	H	-1.0386
204	C	H	0.0000
205	N	H	-1.4076
206	V	H	0.0000
207	N	H	-1.7866
208	H	H	0.0000
209	K	H	-2.6905
210	P	H	-1.5539
211	S	H	-1.8197
212	N	H	-2.4976
213	T	H	-2.0277
214	K	H	-2.6949
215	V	H	-1.7231
216	D	H	-2.5067
217	K	H	-1.8178
218	K	H	-2.0733
219	V	H	0.0000
220	E	H	-2.2424