Project name: 82da2fb572047a7

Chain sequence(s)	X: PFRDCADVYQAGFNKSGIYTIYINNMPEPKKVFCNMDVNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQRQYMLRIELMDWEGNRAYSQYDRFHIGNEKQNYRLYLKGHTGTAGKQSSLILHGADFSTKDADNDNCMCKCALMLTGGWWFDACGPSNLNGMFYTAGQNHGKLNGIKWHYFKGPSYSLRSTTMMIRPLDF
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.1044
• Maximal score value: 1.4277
• Average score: -0.2891
• Total score value: -62.7303

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
3	P	X	-0.1627
4	F	X	0.3040
5	R	X	-0.8746
6	D	X	0.0000
7	C	X	0.0000
8	A	X	0.0000
9	D	X	-0.3140
10	V	X	0.0000
11	Y	X	0.0571
12	Q	X	-1.1385
13	A	X	-0.2565
14	G	X	-0.1887
15	F	X	1.1281
16	N	X	-1.3250
17	K	X	-1.9374
18	S	X	-0.3788
19	G	X	0.0536
20	I	X	0.8456
21	Y	X	0.3691
22	T	X	-0.2181
23	I	X	0.0000
24	Y	X	0.8781
25	I	X	0.0000
26	N	X	-0.9372
27	N	X	-1.3647
28	M	X	-0.0574
29	P	X	-0.4518
30	E	X	-1.3834
31	P	X	-0.4466
32	K	X	-0.6285
33	K	X	-1.7523
34	V	X	0.0000
35	F	X	0.6295
36	C	X	0.0000
37	N	X	-0.1973
38	M	X	0.0000
39	D	X	-1.7022
40	V	X	-0.0773
41	N	X	-1.2626
42	G	X	-0.6526
43	G	X	0.0000
44	G	X	0.0000
45	W	X	0.0000
46	T	X	0.0000
47	V	X	0.0000
48	I	X	0.0000
49	Q	X	0.0000
50	H	X	-0.1841
51	R	X	0.0000
52	E	X	-1.8081
53	D	X	-2.1044
54	G	X	-0.5864
55	S	X	-0.2144
56	L	X	-0.0351
57	D	X	-1.0452
58	F	X	0.0000
59	Q	X	-0.8854
60	R	X	-0.5861
61	G	X	-0.1166
62	W	X	-0.1810
63	K	X	-1.8437
64	E	X	-1.1041
65	Y	X	0.0000
66	K	X	-0.3115
67	M	X	0.3569
68	G	X	0.0121
69	F	X	0.1107
70	G	X	-0.5481
71	N	X	-1.3447
72	P	X	-0.3164
73	S	X	-0.2434
74	G	X	-0.1703
75	E	X	0.0000
76	Y	X	0.0000
77	W	X	0.0000
78	L	X	0.0000
79	G	X	0.0000
80	N	X	0.0000
81	E	X	-0.2703
82	F	X	0.0000
83	I	X	0.0000
84	F	X	0.4045
85	A	X	0.0000
86	I	X	0.0000
87	T	X	0.0000
88	S	X	-0.2503
89	Q	X	-0.3520
90	R	X	-0.8418
91	Q	X	-1.3074
92	Y	X	0.0000
93	M	X	-0.2329
94	L	X	0.0000
95	R	X	0.0000
96	I	X	0.0000
97	E	X	-0.3841
98	L	X	0.0000
99	M	X	0.0200
100	D	X	0.0000
101	W	X	-0.1707
102	E	X	-1.8273
103	G	X	-0.7291
104	N	X	-1.4410
105	R	X	-2.0077
106	A	X	0.0000
107	Y	X	0.3326
108	S	X	0.0000
109	Q	X	-0.1612
110	Y	X	0.0000
111	D	X	-1.8566
112	R	X	-1.7472
113	F	X	0.0000
114	H	X	-0.7243
115	I	X	0.0000
116	G	X	-0.0969
117	N	X	-0.3934
118	E	X	-1.0314
119	K	X	-1.9724
120	Q	X	-1.2202
121	N	X	-0.5554
122	Y	X	0.0000
123	R	X	-0.6756
124	L	X	0.0000
125	Y	X	0.8403
126	L	X	0.0000
127	K	X	-1.7249
128	G	X	-0.6589
129	H	X	-0.2138
130	T	X	-0.1354
131	G	X	-0.2058
132	T	X	-0.1043
133	A	X	0.0000
134	G	X	-0.3237
135	K	X	-1.9401
136	Q	X	-1.5102
137	S	X	0.0000
138	S	X	0.0000
139	L	X	0.0000
140	I	X	0.3886
141	L	X	0.3090
142	H	X	-0.9259
143	G	X	-0.2879
144	A	X	0.0000
145	D	X	-0.3233
146	F	X	0.0000
147	S	X	0.0000
148	T	X	0.0000
149	K	X	-1.3174
150	D	X	-1.9695
151	A	X	-0.6469
152	D	X	-1.8323
153	N	X	-0.6149
154	D	X	-0.5104
155	N	X	-1.2842
156	C	X	0.1393
157	M	X	1.1368
158	C	X	0.1802
159	K	X	-1.6508
160	C	X	0.0000
161	A	X	0.0000
162	L	X	1.2404
163	M	X	0.9309
164	L	X	0.0000
165	T	X	-0.0085
166	G	X	0.0000
167	G	X	0.0000
168	W	X	0.0000
169	W	X	0.0000
170	F	X	0.0000
171	D	X	-0.4338
172	A	X	0.0258
173	C	X	0.0371
174	G	X	-0.1293
175	P	X	-0.0484
176	S	X	0.0000
177	N	X	0.0000
178	L	X	0.0000
179	N	X	0.0000
180	G	X	0.0000
181	M	X	0.4085
182	F	X	0.3667
183	Y	X	0.2219
184	T	X	-0.0056
185	A	X	-0.0360
186	G	X	-0.6362
187	Q	X	-1.0925
188	N	X	0.0000
189	H	X	-1.0747
190	G	X	-0.7179
191	K	X	-0.1948
192	L	X	1.4277
193	N	X	0.0067
194	G	X	0.0000
195	I	X	0.0000
196	K	X	0.0000
197	W	X	0.0000
198	H	X	-0.0700
199	Y	X	0.8841
200	F	X	0.4666
201	K	X	-0.4225
202	G	X	-0.2171
203	P	X	-0.2350
204	S	X	-0.1772
205	Y	X	0.0000
206	S	X	0.0000
207	L	X	0.0000
208	R	X	-0.6194
209	S	X	-0.3360
210	T	X	0.0000
211	T	X	-0.0754
212	M	X	0.0000
213	M	X	0.0000
214	I	X	0.0000
215	R	X	0.0000
216	P	X	0.0000
217	L	X	0.1595
218	D	X	-1.5573
219	F	X	0.4523