Project name: 5ggr:L
Status: done
submitted: 2019-03-20 20:27:29, status changed: 2019-03-20 20:40:05
Settings
|
Chain sequence(s)
|
L: EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQSSNWPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-4.0606
-
Maximal score value
-
1.6561
-
Average score
-
-0.8979
-
Total score value
-
-190.3479
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
L |
-1.7006 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
V |
L |
0.6334 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
-0.4748 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.7032 |
|
| 8 |
P |
L |
-0.4564 |
|
| 9 |
A |
L |
-0.5298 |
|
| 10 |
T |
L |
-0.3223 |
|
| 11 |
L |
L |
-0.1238 |
|
| 12 |
S |
L |
-0.5205 |
|
| 13 |
L |
L |
-0.7184 |
|
| 14 |
S |
L |
-1.0476 |
|
| 15 |
P |
L |
-1.3431 |
|
| 16 |
G |
L |
-1.3410 |
|
| 17 |
E |
L |
-1.8000 |
|
| 18 |
R |
L |
-2.4021 |
|
| 19 |
A |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6076 |
|
| 21 |
L |
L |
0.0000 |
|
| 22 |
S |
L |
-0.8548 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.0599 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-0.9801 |
|
| 27 |
Q |
L |
-1.6951 |
|
| 28 |
S |
L |
-1.2628 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
S |
L |
-0.6745 |
|
| 31 |
S |
L |
-0.4607 |
|
| 32 |
Y |
L |
0.2892 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
A |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.1406 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.4211 |
|
| 39 |
K |
L |
-2.0421 |
|
| 40 |
P |
L |
-1.5581 |
|
| 41 |
G |
L |
-1.4477 |
|
| 42 |
Q |
L |
-2.0440 |
|
| 43 |
A |
L |
-1.2321 |
|
| 44 |
P |
L |
-1.1484 |
|
| 45 |
R |
L |
-1.2528 |
|
| 46 |
L |
L |
-0.2008 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
-0.7025 |
|
| 50 |
D |
L |
-1.3771 |
|
| 51 |
A |
L |
-1.0688 |
|
| 52 |
S |
L |
-1.4595 |
|
| 53 |
N |
L |
-2.2841 |
|
| 54 |
R |
L |
-2.4256 |
|
| 55 |
A |
L |
-1.1699 |
|
| 56 |
T |
L |
-0.7229 |
|
| 57 |
G |
L |
-0.6936 |
|
| 58 |
I |
L |
-0.6442 |
|
| 59 |
P |
L |
-0.5492 |
|
| 60 |
A |
L |
-0.5209 |
|
| 61 |
R |
L |
-0.8880 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.8656 |
|
| 64 |
G |
L |
-0.8450 |
|
| 65 |
S |
L |
-1.0148 |
|
| 66 |
G |
L |
-1.2476 |
|
| 67 |
S |
L |
-1.1719 |
|
| 68 |
G |
L |
-1.2237 |
|
| 69 |
T |
L |
-1.9353 |
|
| 70 |
D |
L |
-2.6869 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.8336 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.5716 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.2561 |
|
| 77 |
S |
L |
-1.3890 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
E |
L |
-2.1026 |
|
| 80 |
P |
L |
-1.5555 |
|
| 81 |
E |
L |
-2.3047 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
-0.7329 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
V |
L |
-0.6663 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.0073 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.3234 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
S |
L |
-0.4840 |
|
| 92 |
S |
L |
-0.5412 |
|
| 93 |
N |
L |
-0.9749 |
|
| 94 |
W |
L |
-0.3756 |
|
| 95 |
P |
L |
-0.9247 |
|
| 96 |
R |
L |
-1.5922 |
|
| 97 |
T |
L |
-0.2949 |
|
| 98 |
F |
L |
0.7089 |
|
| 99 |
G |
L |
0.0570 |
|
| 100 |
Q |
L |
-0.9269 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.2611 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
0.0000 |
|
| 106 |
I |
L |
-0.5929 |
|
| 107 |
K |
L |
-1.1322 |
|
| 108 |
R |
L |
-1.5563 |
|
| 109 |
T |
L |
-0.1070 |
|
| 110 |
V |
L |
0.9108 |
|
| 111 |
A |
L |
0.1124 |
|
| 112 |
A |
L |
-0.1119 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.0964 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.4783 |
|
| 117 |
I |
L |
1.4306 |
|
| 118 |
F |
L |
1.6561 |
|
| 119 |
P |
L |
-0.0223 |
|
| 120 |
P |
L |
-0.8551 |
|
| 121 |
S |
L |
-1.9359 |
|
| 122 |
D |
L |
-3.3631 |
|
| 123 |
E |
L |
-3.6031 |
|
| 124 |
Q |
L |
-2.8818 |
|
| 125 |
L |
L |
-2.6205 |
|
| 126 |
K |
L |
-3.1365 |
|
| 127 |
S |
L |
-2.0420 |
|
| 128 |
G |
L |
-1.7068 |
|
| 129 |
T |
L |
-1.3425 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
-0.0681 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7536 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.6341 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.7055 |
|
| 138 |
N |
L |
-1.5229 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.2015 |
|
| 142 |
R |
L |
-2.0716 |
|
| 143 |
E |
L |
-2.8401 |
|
| 144 |
A |
L |
-2.1724 |
|
| 145 |
K |
L |
-2.6673 |
|
| 146 |
V |
L |
-1.5622 |
|
| 147 |
Q |
L |
-1.7500 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-1.2453 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.7098 |
|
| 152 |
N |
L |
-1.4400 |
|
| 153 |
A |
L |
-0.3783 |
|
| 154 |
L |
L |
0.4827 |
|
| 155 |
Q |
L |
-0.8627 |
|
| 156 |
S |
L |
-1.1356 |
|
| 157 |
G |
L |
-1.3252 |
|
| 158 |
N |
L |
-1.4586 |
|
| 159 |
S |
L |
-1.8541 |
|
| 160 |
Q |
L |
-2.4132 |
|
| 161 |
E |
L |
-2.4690 |
|
| 162 |
S |
L |
-1.1950 |
|
| 163 |
V |
L |
-0.4357 |
|
| 164 |
T |
L |
-1.0934 |
|
| 165 |
E |
L |
-2.1937 |
|
| 166 |
Q |
L |
-2.1620 |
|
| 167 |
D |
L |
-2.7569 |
|
| 168 |
S |
L |
-2.2026 |
|
| 169 |
K |
L |
-2.9394 |
|
| 170 |
D |
L |
-3.1920 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.9130 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.4068 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.7314 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.3728 |
|
| 181 |
L |
L |
-0.6907 |
|
| 182 |
S |
L |
-1.6462 |
|
| 183 |
K |
L |
-2.4557 |
|
| 184 |
A |
L |
-2.3620 |
|
| 185 |
D |
L |
-3.1741 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.9306 |
|
| 188 |
K |
L |
-4.0606 |
|
| 189 |
H |
L |
-3.5152 |
|
| 190 |
K |
L |
-3.2927 |
|
| 191 |
V |
L |
-1.6475 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
-1.1263 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-1.1106 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2175 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.3125 |
|
| 200 |
G |
L |
-0.3182 |
|
| 201 |
L |
L |
-0.2622 |
|
| 202 |
S |
L |
-0.5133 |
|
| 203 |
S |
L |
-0.3987 |
|
| 204 |
P |
L |
-0.4265 |
|
| 205 |
V |
L |
0.2792 |
|
| 206 |
T |
L |
-0.2815 |
|
| 207 |
K |
L |
-0.2519 |
|
| 208 |
S |
L |
-0.2772 |
|
| 209 |
F |
L |
-0.6105 |
|
| 210 |
N |
L |
-1.9376 |
|
| 211 |
R |
L |
-2.7055 |
|
| 212 |
G |
L |
-1.4547 |
|