Project name: 6bio:H

Chain sequence(s)	H: VQLVESGGGLVQPGGSLRLSCAASGFNIKDTYIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGDGFYAMDYWGQGTLVTVSSASTKGPSVFPLAPSTAALGCCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9309
• Maximal score value: 2.4985
• Average score: -0.4997
• Total score value: -105.9378

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	H	0.8902
3	Q	H	-0.1975
4	L	H	0.0000
5	V	H	0.4002
6	E	H	0.0000
7	S	H	-0.5075
8	G	H	-0.8484
9	G	H	-0.4345
10	G	H	0.0448
11	L	H	0.1235
12	V	H	-0.5843
13	Q	H	-1.5397
14	P	H	-1.6660
15	G	H	-1.4109
16	G	H	-1.1066
17	S	H	-1.0686
18	L	H	-1.0909
19	R	H	-1.9985
20	L	H	0.0000
21	S	H	-0.3737
22	C	H	0.0000
23	A	H	-0.2980
24	A	H	0.0000
25	S	H	-0.3394
26	G	H	-0.2664
27	F	H	-0.7651
28	N	H	-2.0969
29	I	H	0.0000
30	K	H	-2.6358
31	D	H	-2.8851
32	T	H	0.0000
33	Y	H	-0.6773
34	I	H	0.0000
35	H	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.5751
40	A	H	-1.1227
41	P	H	-1.0648
42	G	H	-1.5850
43	K	H	-2.1269
44	G	H	-1.0202
45	L	H	0.4642
46	E	H	-0.4914
47	W	H	0.0735
48	V	H	0.0000
49	A	H	0.0000
50	R	H	-1.0646
51	I	H	0.0000
52	Y	H	-0.5139
53	P	H	0.0000
54	T	H	-1.2302
55	N	H	-1.0763
56	G	H	-0.4538
57	Y	H	0.3732
58	T	H	-0.6648
59	R	H	-2.1694
60	Y	H	-1.9685
61	A	H	-1.9120
62	D	H	-2.7586
63	S	H	-1.8450
64	V	H	0.0000
65	K	H	-2.9309
66	G	H	-1.7816
67	R	H	-1.4822
68	F	H	0.0000
69	T	H	-1.0682
70	I	H	0.0000
71	S	H	-0.1227
72	A	H	-0.7139
73	D	H	-1.4206
74	T	H	-1.8024
75	S	H	-1.5666
76	K	H	-2.2169
77	N	H	-1.7902
78	T	H	-1.0106
79	A	H	0.0000
80	Y	H	-0.3428
81	L	H	0.0000
82	Q	H	-1.0926
83	M	H	0.0000
84	N	H	-1.3117
85	S	H	-1.1711
86	L	H	0.0000
87	R	H	-2.4666
88	A	H	-1.7926
89	E	H	-2.3350
90	D	H	0.0000
91	T	H	-0.7355
92	A	H	0.0000
93	V	H	0.4173
94	Y	H	0.0000
95	Y	H	0.4070
96	C	H	0.0000
97	S	H	0.0000
98	R	H	-0.3011
99	W	H	-0.0561
100	G	H	0.0000
101	G	H	-0.4905
102	D	H	-1.4003
103	G	H	0.2735
104	F	H	1.8161
105	Y	H	1.6288
106	A	H	0.8138
107	M	H	0.4212
108	D	H	0.2889
109	Y	H	0.5447
110	W	H	0.4420
111	G	H	-0.1495
112	Q	H	-0.8725
113	G	H	0.0000
114	T	H	0.0180
115	L	H	0.3533
116	V	H	0.0000
117	T	H	-0.3538
118	V	H	0.0000
119	S	H	-0.7443
120	S	H	-0.6690
121	A	H	-0.4296
122	S	H	-0.5210
123	T	H	-0.6978
124	K	H	-1.1290
125	G	H	-1.4166
126	P	H	0.0000
127	S	H	-0.0413
128	V	H	0.0000
129	F	H	1.1984
130	P	H	0.2977
131	L	H	0.5848
132	A	H	-0.3256
133	P	H	0.0000
134	S	H	-0.4332
142	T	H	-0.2701
143	A	H	0.0000
144	A	H	0.0779
145	L	H	0.0000
146	G	H	0.0000
147	C	H	0.0000
148	L	H	0.8862
149	V	H	0.0000
150	K	H	-0.0518
151	D	H	-0.4642
152	Y	H	0.0000
153	F	H	0.0000
154	P	H	0.0000
155	E	H	-0.4357
156	P	H	-0.7929
157	V	H	-0.8125
158	T	H	-0.6951
159	V	H	-0.1522
160	S	H	-0.3874
161	W	H	0.0000
162	N	H	-0.7042
163	S	H	-0.6295
164	G	H	-0.5827
165	A	H	-0.2517
166	L	H	-0.0070
167	T	H	-0.2992
168	S	H	-0.3620
169	G	H	-0.4523
170	V	H	0.0522
171	H	H	-0.4103
172	T	H	0.2753
173	F	H	1.0068
174	P	H	0.7393
175	A	H	1.3041
176	V	H	2.4985
177	L	H	2.0534
178	Q	H	0.6599
179	S	H	0.0705
180	S	H	-0.2153
181	G	H	0.2245
182	L	H	0.3339
183	Y	H	0.8760
184	S	H	0.0000
185	L	H	0.9852
186	S	H	0.7567
187	S	H	0.0000
188	V	H	0.4585
189	V	H	0.0000
190	T	H	-0.2293
191	V	H	0.0000
192	P	H	-0.5339
193	S	H	-0.4838
194	S	H	-0.5598
195	S	H	-0.6453
196	L	H	-0.8936
197	G	H	-1.1902
198	T	H	-0.9845
199	Q	H	-1.4451
200	T	H	-1.1151
201	Y	H	0.0000
202	I	H	-0.9093
203	C	H	0.0000
204	N	H	-1.3751
205	V	H	0.0000
206	N	H	-2.2501
207	H	H	0.0000
208	K	H	-2.8632
209	P	H	-1.6138
210	S	H	-1.8633
211	N	H	-2.6724
212	T	H	-2.2048
213	K	H	-2.8007
214	V	H	-1.5443
215	D	H	-2.1480
216	K	H	-1.7227
217	K	H	-1.8425
218	V	H	0.0000
219	E	H	-2.3956
220	P	H	-1.1891