Project name: 3eo9:L
Status: done
submitted: 2019-03-20 20:08:04, status changed: 2019-03-20 20:18:24
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCRASKTISKYLAWYQQKPGKAPKLLIYSGSTLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQHNEYPLTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7439
-
Maximal score value
-
1.4485
-
Average score
-
-0.8487
-
Total score value
-
-180.7639
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-2.1217 |
|
| 2 |
I |
L |
-1.7063 |
|
| 3 |
Q |
L |
-1.8894 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-1.1662 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.8553 |
|
| 8 |
P |
L |
-0.6605 |
|
| 9 |
S |
L |
-0.9715 |
|
| 10 |
S |
L |
-0.9201 |
|
| 11 |
L |
L |
-0.4957 |
|
| 12 |
S |
L |
-0.7539 |
|
| 13 |
A |
L |
0.0000 |
|
| 14 |
S |
L |
-0.3667 |
|
| 15 |
V |
L |
0.4187 |
|
| 16 |
G |
L |
-0.7212 |
|
| 17 |
D |
L |
-1.6352 |
|
| 18 |
R |
L |
-2.2897 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6298 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.7513 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.5794 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-2.0872 |
|
| 27 |
K |
L |
-2.5539 |
|
| 28 |
T |
L |
-1.6111 |
|
| 29 |
I |
L |
0.0000 |
|
| 30 |
S |
L |
-1.5784 |
|
| 31 |
K |
L |
-1.8251 |
|
| 32 |
Y |
L |
-0.7278 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
A |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.1027 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.6351 |
|
| 39 |
K |
L |
-2.1607 |
|
| 40 |
P |
L |
-1.4406 |
|
| 41 |
G |
L |
-1.6454 |
|
| 42 |
K |
L |
-2.5057 |
|
| 43 |
A |
L |
-1.4961 |
|
| 44 |
P |
L |
-1.4034 |
|
| 45 |
K |
L |
-1.6502 |
|
| 46 |
L |
L |
-0.2642 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
0.4272 |
|
| 50 |
S |
L |
-0.2460 |
|
| 51 |
G |
L |
0.0000 |
|
| 52 |
S |
L |
-0.4121 |
|
| 53 |
T |
L |
0.0324 |
|
| 54 |
L |
L |
0.1115 |
|
| 55 |
Q |
L |
-0.5331 |
|
| 56 |
S |
L |
-0.5286 |
|
| 57 |
G |
L |
-0.6101 |
|
| 58 |
V |
L |
-0.4091 |
|
| 59 |
P |
L |
-0.3921 |
|
| 60 |
S |
L |
-0.4032 |
|
| 61 |
R |
L |
-0.7829 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.3234 |
|
| 64 |
G |
L |
-0.2578 |
|
| 65 |
S |
L |
-0.9141 |
|
| 66 |
G |
L |
-1.3796 |
|
| 67 |
S |
L |
-1.5363 |
|
| 68 |
G |
L |
-1.5440 |
|
| 69 |
T |
L |
-2.0135 |
|
| 70 |
D |
L |
-2.3473 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7452 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6185 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.3354 |
|
| 77 |
S |
L |
-1.1539 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-0.8401 |
|
| 80 |
P |
L |
-0.8430 |
|
| 81 |
E |
L |
-1.8836 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
-0.5794 |
|
| 84 |
A |
L |
-1.0293 |
|
| 85 |
T |
L |
0.0000 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
-0.0561 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
H |
L |
-0.3763 |
|
| 92 |
N |
L |
-1.2277 |
|
| 93 |
E |
L |
-1.4696 |
|
| 94 |
Y |
L |
0.2496 |
|
| 95 |
P |
L |
0.1678 |
|
| 96 |
L |
L |
0.7767 |
|
| 97 |
T |
L |
0.3808 |
|
| 98 |
F |
L |
1.1931 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
Q |
L |
-1.1627 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-2.0018 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-0.9943 |
|
| 106 |
I |
L |
-0.0809 |
|
| 107 |
K |
L |
-1.1827 |
|
| 108 |
R |
L |
-1.0634 |
|
| 109 |
T |
L |
-0.2272 |
|
| 110 |
V |
L |
0.1028 |
|
| 111 |
A |
L |
-0.2285 |
|
| 112 |
A |
L |
-0.2560 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1335 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.2706 |
|
| 117 |
I |
L |
1.2107 |
|
| 118 |
F |
L |
1.4485 |
|
| 119 |
P |
L |
-0.1792 |
|
| 120 |
P |
L |
-0.7293 |
|
| 121 |
S |
L |
-1.7701 |
|
| 122 |
D |
L |
-3.2180 |
|
| 123 |
E |
L |
-3.3745 |
|
| 124 |
Q |
L |
-2.3758 |
|
| 125 |
L |
L |
-2.4400 |
|
| 126 |
K |
L |
-2.9247 |
|
| 127 |
S |
L |
-1.7988 |
|
| 128 |
G |
L |
-1.2471 |
|
| 129 |
T |
L |
-1.1111 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0056 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7221 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.5711 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.5520 |
|
| 138 |
N |
L |
-1.2673 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.7991 |
|
| 142 |
R |
L |
-2.9487 |
|
| 143 |
E |
L |
-3.1449 |
|
| 144 |
A |
L |
-2.2894 |
|
| 145 |
K |
L |
-2.3627 |
|
| 146 |
V |
L |
-0.9769 |
|
| 147 |
Q |
L |
-0.4739 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.3760 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.7394 |
|
| 152 |
N |
L |
-1.3927 |
|
| 153 |
A |
L |
-0.1582 |
|
| 154 |
L |
L |
0.7868 |
|
| 155 |
Q |
L |
-0.2646 |
|
| 156 |
S |
L |
-0.6566 |
|
| 157 |
G |
L |
-1.4537 |
|
| 158 |
N |
L |
-1.9191 |
|
| 159 |
S |
L |
-1.8378 |
|
| 160 |
Q |
L |
-2.4375 |
|
| 161 |
E |
L |
-2.2476 |
|
| 162 |
S |
L |
-1.3416 |
|
| 163 |
V |
L |
-0.7997 |
|
| 164 |
T |
L |
-1.2106 |
|
| 165 |
E |
L |
-2.2135 |
|
| 166 |
Q |
L |
-1.8664 |
|
| 167 |
D |
L |
-1.9659 |
|
| 168 |
S |
L |
-1.7520 |
|
| 169 |
K |
L |
-2.3529 |
|
| 170 |
D |
L |
-1.9549 |
|
| 171 |
S |
L |
-1.7684 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.9433 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.4238 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.7496 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.8693 |
|
| 181 |
L |
L |
0.0000 |
|
| 182 |
S |
L |
-1.1662 |
|
| 183 |
K |
L |
-2.1341 |
|
| 184 |
A |
L |
-2.0018 |
|
| 185 |
D |
L |
-2.7696 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.7334 |
|
| 188 |
K |
L |
-3.7439 |
|
| 189 |
H |
L |
-3.0467 |
|
| 190 |
K |
L |
-3.1756 |
|
| 191 |
V |
L |
-1.2226 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.6787 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2054 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.7723 |
|
| 200 |
G |
L |
-0.5059 |
|
| 201 |
L |
L |
-0.2373 |
|
| 202 |
S |
L |
-0.4502 |
|
| 203 |
S |
L |
-0.4235 |
|
| 204 |
P |
L |
-0.5891 |
|
| 205 |
V |
L |
-0.0632 |
|
| 206 |
T |
L |
-0.3487 |
|
| 207 |
K |
L |
-0.2735 |
|
| 208 |
S |
L |
-0.1461 |
|
| 209 |
F |
L |
-0.6954 |
|
| 210 |
N |
L |
-1.8163 |
|
| 211 |
R |
L |
-2.5786 |
|
| 212 |
G |
L |
-2.3442 |
|
| 213 |
E |
L |
-2.5152 |
|