Project name: 5t1l:B

Chain sequence(s)	B: VQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9151
• Maximal score value: 2.3931
• Average score: -0.4746
• Total score value: -102.0284

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	B	0.6883
3	Q	B	-0.9547
4	L	B	0.0000
5	K	B	-2.2928
6	Q	B	0.0000
7	S	B	-0.7875
8	G	B	-0.9920
9	P	B	-0.4262
10	G	B	-0.4003
11	L	B	-0.1514
12	V	B	0.0000
13	Q	B	-1.7894
14	P	B	-1.5908
15	S	B	-1.5696
16	Q	B	-1.8868
17	S	B	-1.5156
18	L	B	0.0000
19	S	B	-0.5642
20	I	B	0.0000
21	T	B	-0.4741
22	C	B	0.0000
23	T	B	-1.1700
24	V	B	0.0000
25	S	B	-0.7971
26	G	B	-0.1669
27	F	B	-0.1149
28	S	B	-0.7705
29	L	B	0.0000
30	T	B	-0.8922
31	N	B	-0.8815
32	Y	B	0.3994
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.2604
40	S	B	0.0000
41	P	B	-1.1232
42	G	B	-1.6687
43	K	B	-1.9921
44	G	B	-0.6104
45	L	B	0.8191
46	E	B	0.0000
47	W	B	0.4589
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.5769
53	S	B	-0.6407
54	G	B	-1.2260
55	G	B	-1.5319
56	N	B	-1.9585
57	T	B	-1.5189
58	D	B	-1.5063
59	Y	B	-0.6848
60	N	B	-0.6476
61	T	B	-0.5368
62	P	B	-0.4740
63	F	B	0.0000
64	T	B	-0.5981
65	S	B	-0.5573
66	R	B	-0.9019
67	L	B	0.0000
68	S	B	-0.9974
69	I	B	0.0000
70	N	B	-1.6769
71	K	B	-1.3859
72	D	B	-1.6816
73	N	B	-2.0894
74	S	B	-1.6223
75	K	B	-2.3212
76	S	B	-1.5756
77	Q	B	-1.4687
78	V	B	0.0000
79	F	B	-0.2031
80	F	B	0.0000
81	K	B	-1.2730
82	M	B	0.0000
83	N	B	-1.5411
84	S	B	-1.4476
85	L	B	0.0000
86	Q	B	-2.1850
87	S	B	-1.6022
88	N	B	-2.0913
89	D	B	0.0000
90	T	B	-0.7035
91	A	B	0.0000
92	I	B	0.5011
93	Y	B	0.0000
94	Y	B	-0.0986
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.8014
100	T	B	1.3791
101	Y	B	1.8587
102	Y	B	1.7716
103	D	B	0.8196
104	Y	B	0.8061
105	E	B	0.3163
106	F	B	0.7157
107	A	B	0.9517
108	Y	B	0.7745
109	W	B	0.1422
110	G	B	0.0000
111	Q	B	-1.5216
112	G	B	-0.6389
113	T	B	0.0000
114	L	B	0.2312
115	V	B	0.0000
116	T	B	-0.3803
117	V	B	0.0000
118	S	B	-0.6360
119	A	B	-0.4376
120	A	B	-0.3369
121	S	B	-0.5426
122	T	B	-0.7117
123	K	B	-1.1941
124	G	B	-1.4409
125	P	B	0.0000
126	S	B	-0.0975
127	V	B	0.0000
128	F	B	0.9879
129	P	B	-0.1467
130	L	B	0.3185
131	A	B	-0.9743
132	P	B	0.0000
133	S	B	-0.8410
139	G	B	-0.7614
140	G	B	-0.8830
141	T	B	-0.6069
142	A	B	0.0000
143	A	B	0.0878
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.7196
148	V	B	0.0000
149	K	B	-0.1814
150	D	B	-0.6489
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.1483
155	P	B	-0.5576
156	V	B	-0.6752
157	T	B	-0.6442
158	V	B	-0.2959
159	S	B	-0.4794
160	W	B	0.0000
161	N	B	-0.9004
162	S	B	-0.6865
163	G	B	-0.5771
164	A	B	-0.2510
165	L	B	-0.0373
166	T	B	-0.2924
167	S	B	-0.3684
168	G	B	-0.4607
169	V	B	0.0417
170	H	B	-0.3679
171	T	B	0.1881
172	F	B	0.9986
173	P	B	0.7208
174	A	B	1.2509
175	V	B	2.3931
176	L	B	1.9463
177	Q	B	0.5758
178	S	B	0.0298
179	S	B	-0.2555
180	G	B	0.1626
181	L	B	0.2572
182	Y	B	0.7786
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.6980
186	S	B	0.0000
187	V	B	0.4673
188	V	B	0.0000
189	T	B	-0.2014
190	V	B	0.0000
191	P	B	-0.5556
192	S	B	-0.6257
193	S	B	-0.6189
194	S	B	-0.6292
195	L	B	-0.7884
196	G	B	-0.9335
197	T	B	-0.7133
198	Q	B	-1.1749
199	T	B	-1.1328
200	Y	B	0.0000
201	I	B	-1.4674
202	C	B	0.0000
203	N	B	-1.5857
204	V	B	0.0000
205	N	B	-2.1310
206	H	B	0.0000
207	K	B	-2.6856
208	P	B	-1.5331
209	S	B	-1.7929
210	N	B	-2.5378
211	T	B	-2.0789
212	K	B	-2.7795
213	V	B	-1.8227
214	D	B	-2.6861
215	K	B	-2.1960
216	R	B	-2.6794
217	V	B	0.0000
218	E	B	-2.9151
219	P	B	-1.9611
220	K	B	-2.3688
221	S	B	-1.3442