Project name: 5jxe:D
Status: done
submitted: 2019-03-20 20:03:14, status changed: 2019-03-20 20:13:07
Settings
|
Chain sequence(s)
|
D: QVQLVQSGVEVKKPGASVKVSCKASGYTFTNYYMYWVRQAPGQGLEWMGGINPSNGGTNFNEKFKNRVTLTTDSSTTTAYMELKSLQFDDTAVYYCARRDYRFDMGFDYWGQGTTVTVSSASTKGPSVFPLAPLGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVTCNVDHKPSNTKVDKRV
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6407
-
Maximal score value
-
2.3863
-
Average score
-
-0.4335
-
Total score value
-
-85.3978
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
D |
-1.5247 |
|
| 2 |
V |
D |
-1.1404 |
|
| 3 |
Q |
D |
-1.0432 |
|
| 4 |
L |
D |
0.0000 |
|
| 5 |
V |
D |
0.9028 |
|
| 6 |
Q |
D |
0.0000 |
|
| 7 |
S |
D |
-0.0351 |
|
| 8 |
G |
D |
0.4390 |
|
| 9 |
V |
D |
1.5704 |
|
| 10 |
E |
D |
0.4892 |
|
| 11 |
V |
D |
0.5536 |
|
| 12 |
K |
D |
-1.0063 |
|
| 13 |
K |
D |
-1.8642 |
|
| 14 |
P |
D |
-1.3452 |
|
| 15 |
G |
D |
-1.3591 |
|
| 16 |
A |
D |
-1.4616 |
|
| 17 |
S |
D |
-1.7747 |
|
| 18 |
V |
D |
0.0000 |
|
| 19 |
K |
D |
-2.0092 |
|
| 20 |
V |
D |
0.0000 |
|
| 21 |
S |
D |
-0.3257 |
|
| 22 |
C |
D |
0.0000 |
|
| 23 |
K |
D |
-0.5294 |
|
| 24 |
A |
D |
0.0000 |
|
| 25 |
S |
D |
-0.7227 |
|
| 26 |
G |
D |
-1.0587 |
|
| 27 |
Y |
D |
-0.4068 |
|
| 28 |
T |
D |
-0.0755 |
|
| 29 |
F |
D |
-0.1345 |
|
| 30 |
T |
D |
-0.2415 |
|
| 31 |
N |
D |
-0.4569 |
|
| 32 |
Y |
D |
0.0792 |
|
| 33 |
Y |
D |
-0.0549 |
|
| 34 |
M |
D |
0.0000 |
|
| 35 |
Y |
D |
0.2688 |
|
| 36 |
W |
D |
0.0000 |
|
| 37 |
V |
D |
0.0000 |
|
| 38 |
R |
D |
0.0000 |
|
| 39 |
Q |
D |
-0.2497 |
|
| 40 |
A |
D |
-0.9283 |
|
| 41 |
P |
D |
-0.9990 |
|
| 42 |
G |
D |
-1.1641 |
|
| 43 |
Q |
D |
-1.5219 |
|
| 44 |
G |
D |
-0.6123 |
|
| 45 |
L |
D |
0.8029 |
|
| 46 |
E |
D |
0.1669 |
|
| 47 |
W |
D |
0.2994 |
|
| 48 |
M |
D |
0.0000 |
|
| 49 |
G |
D |
0.0000 |
|
| 50 |
G |
D |
0.0000 |
|
| 51 |
I |
D |
0.0000 |
|
| 52 |
N |
D |
-0.8055 |
|
| 53 |
P |
D |
0.0000 |
|
| 54 |
S |
D |
-1.0979 |
|
| 55 |
N |
D |
-1.6838 |
|
| 56 |
G |
D |
-1.3312 |
|
| 57 |
G |
D |
-1.1728 |
|
| 58 |
T |
D |
-0.9847 |
|
| 59 |
N |
D |
-1.7319 |
|
| 60 |
F |
D |
-1.8523 |
|
| 61 |
N |
D |
-2.2065 |
|
| 62 |
E |
D |
-3.6289 |
|
| 63 |
K |
D |
-3.3038 |
|
| 64 |
F |
D |
0.0000 |
|
| 65 |
K |
D |
-3.6407 |
|
| 66 |
N |
D |
-2.9258 |
|
| 67 |
R |
D |
-2.4589 |
|
| 68 |
V |
D |
0.0000 |
|
| 69 |
T |
D |
-1.1258 |
|
| 70 |
L |
D |
0.0000 |
|
| 71 |
T |
D |
-0.5514 |
|
| 72 |
T |
D |
-0.9833 |
|
| 73 |
D |
D |
-1.4057 |
|
| 74 |
S |
D |
-1.1263 |
|
| 75 |
S |
D |
-0.7125 |
|
| 76 |
T |
D |
-0.7055 |
|
| 77 |
T |
D |
-0.7615 |
|
| 78 |
T |
D |
0.0000 |
|
| 79 |
A |
D |
0.0000 |
|
| 80 |
Y |
D |
-0.4984 |
|
| 81 |
M |
D |
0.0000 |
|
| 82 |
E |
D |
-1.5040 |
|
| 83 |
L |
D |
0.0000 |
|
| 84 |
K |
D |
-2.3314 |
|
| 85 |
S |
D |
-1.6640 |
|
| 86 |
L |
D |
0.0000 |
|
| 87 |
Q |
D |
-1.0847 |
|
| 88 |
F |
D |
0.2721 |
|
| 89 |
D |
D |
-1.1248 |
|
| 90 |
D |
D |
0.0000 |
|
| 91 |
T |
D |
-0.2523 |
|
| 92 |
A |
D |
0.0000 |
|
| 93 |
V |
D |
0.4161 |
|
| 94 |
Y |
D |
0.0000 |
|
| 95 |
Y |
D |
0.4076 |
|
| 96 |
C |
D |
0.0000 |
|
| 97 |
A |
D |
0.0000 |
|
| 98 |
R |
D |
0.0000 |
|
| 99 |
R |
D |
-0.2275 |
|
| 100 |
D |
D |
0.0000 |
|
| 101 |
Y |
D |
-0.0136 |
|
| 102 |
R |
D |
-0.8655 |
|
| 103 |
F |
D |
0.6054 |
|
| 104 |
D |
D |
-0.7639 |
|
| 105 |
M |
D |
0.2006 |
|
| 106 |
G |
D |
-0.2544 |
|
| 107 |
F |
D |
-0.1232 |
|
| 108 |
D |
D |
-1.1829 |
|
| 109 |
Y |
D |
-0.2100 |
|
| 110 |
W |
D |
0.3464 |
|
| 111 |
G |
D |
0.0000 |
|
| 112 |
Q |
D |
-0.6785 |
|
| 113 |
G |
D |
0.0013 |
|
| 114 |
T |
D |
0.0000 |
|
| 115 |
T |
D |
0.5532 |
|
| 116 |
V |
D |
0.0000 |
|
| 117 |
T |
D |
0.0000 |
|
| 118 |
V |
D |
0.0000 |
|
| 119 |
S |
D |
0.0000 |
|
| 120 |
S |
D |
-0.6292 |
|
| 121 |
A |
D |
-0.6152 |
|
| 122 |
S |
D |
-0.6687 |
|
| 123 |
T |
D |
-0.7246 |
|
| 124 |
K |
D |
-1.1955 |
|
| 125 |
G |
D |
-1.4140 |
|
| 126 |
P |
D |
-0.6607 |
|
| 127 |
S |
D |
-0.1526 |
|
| 128 |
V |
D |
0.0000 |
|
| 129 |
F |
D |
0.8933 |
|
| 130 |
P |
D |
0.9123 |
|
| 131 |
L |
D |
1.4872 |
|
| 132 |
A |
D |
1.1330 |
|
| 133 |
P |
D |
0.1294 |
|
| 145 |
L |
D |
2.0438 |
|
| 146 |
G |
D |
0.0000 |
|
| 147 |
C |
D |
0.0000 |
|
| 148 |
L |
D |
0.5520 |
|
| 149 |
V |
D |
0.0000 |
|
| 150 |
K |
D |
-0.2716 |
|
| 151 |
D |
D |
-0.4731 |
|
| 152 |
Y |
D |
0.0000 |
|
| 153 |
F |
D |
0.0000 |
|
| 154 |
P |
D |
-0.6721 |
|
| 155 |
E |
D |
-1.1283 |
|
| 156 |
P |
D |
-1.1645 |
|
| 157 |
V |
D |
-0.9008 |
|
| 158 |
T |
D |
-0.7093 |
|
| 159 |
V |
D |
-0.2516 |
|
| 160 |
S |
D |
-0.6768 |
|
| 161 |
W |
D |
0.0000 |
|
| 162 |
N |
D |
-1.6200 |
|
| 163 |
S |
D |
-1.0684 |
|
| 164 |
G |
D |
-0.7638 |
|
| 165 |
A |
D |
-0.4182 |
|
| 166 |
L |
D |
0.0208 |
|
| 167 |
T |
D |
-0.3841 |
|
| 168 |
S |
D |
-0.1293 |
|
| 169 |
G |
D |
-0.1655 |
|
| 170 |
V |
D |
0.2710 |
|
| 171 |
H |
D |
-0.2808 |
|
| 172 |
T |
D |
0.5510 |
|
| 173 |
F |
D |
1.6805 |
|
| 174 |
P |
D |
1.0196 |
|
| 175 |
A |
D |
1.2499 |
|
| 176 |
V |
D |
2.3863 |
|
| 177 |
L |
D |
1.8121 |
|
| 178 |
Q |
D |
0.5748 |
|
| 179 |
S |
D |
0.0385 |
|
| 180 |
S |
D |
-0.2608 |
|
| 181 |
G |
D |
0.3522 |
|
| 182 |
L |
D |
0.0742 |
|
| 183 |
Y |
D |
0.0000 |
|
| 184 |
S |
D |
0.6765 |
|
| 185 |
L |
D |
0.0000 |
|
| 186 |
S |
D |
0.7938 |
|
| 187 |
S |
D |
0.0000 |
|
| 188 |
V |
D |
1.2332 |
|
| 189 |
V |
D |
0.0000 |
|
| 190 |
T |
D |
0.9595 |
|
| 191 |
V |
D |
1.9497 |
|
| 202 |
T |
D |
-1.1480 |
|
| 203 |
C |
D |
0.0000 |
|
| 204 |
N |
D |
-1.9370 |
|
| 205 |
V |
D |
0.0000 |
|
| 206 |
D |
D |
-2.1442 |
|
| 207 |
H |
D |
0.0000 |
|
| 208 |
K |
D |
-2.8708 |
|
| 209 |
P |
D |
-1.7307 |
|
| 210 |
S |
D |
-1.8608 |
|
| 211 |
N |
D |
-2.6151 |
|
| 212 |
T |
D |
-2.0934 |
|
| 213 |
K |
D |
-2.7540 |
|
| 214 |
V |
D |
-1.6224 |
|
| 215 |
D |
D |
-2.9483 |
|
| 216 |
K |
D |
-1.8083 |
|
| 217 |
R |
D |
-1.7337 |
|
| 218 |
V |
D |
1.1203 |
|