Project name: CD47-m7

Chain sequence(s)	H: EVQLLESGGGLVQPGGSLRLSCAASGFTFTNYAMSWVRQAPGKGLEWVSSISTGGSTFYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCVRGLGVHYFGYSVMDYWGQGTTVTVSS; L: DIVMTQTPPSLPVNPGEPASISCRSSQSLVHGDGYIYLHWYLQKPGQSPQLLIYKVGNRLSGVPDRFSGSGSGSDFTLKISWVEAEDVGVYYCFQSTHIPPTFGGGTKLEIKRTV
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.1541
• Maximal score value: 2.0446
• Average score: -0.2366
• Total score value: -56.0852

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	L	-1.7894
2	I	L	0.0000
3	V	L	1.7728
4	M	L	0.0000
5	T	L	-0.1894
6	Q	L	-0.1404
7	T	L	-0.1083
8	P	L	-0.1472
9	P	L	-0.3100
10	S	L	-0.3236
11	L	L	0.1258
12	P	L	-0.3188
13	V	L	0.0000
14	N	L	-1.0193
15	P	L	-0.3153
16	G	L	-0.6271
17	E	L	-1.6355
18	P	L	-0.4244
19	A	L	0.0000
20	S	L	-0.4161
21	I	L	0.0000
22	S	L	-0.0751
23	C	L	0.0000
24	R	L	-1.0686
25	S	L	0.0000
26	S	L	-0.4309
27	Q	L	-1.2715
28	S	L	-0.4227
29	L	L	0.0000
30	V	L	1.1998
31	H	L	-0.1351
32	G	L	-0.8437
33	D	L	-1.9612
34	G	L	-0.7211
35	Y	L	0.3829
36	I	L	0.4831
37	Y	L	0.0000
38	L	L	0.0000
39	H	L	0.0000
40	W	L	0.0000
41	Y	L	0.0000
42	L	L	0.0000
43	Q	L	-0.2544
44	K	L	-0.5419
45	P	L	-0.4254
46	G	L	-0.6817
47	Q	L	-1.0005
48	S	L	-0.1952
49	P	L	0.0000
50	Q	L	-0.8365
51	L	L	0.0000
52	L	L	0.0000
53	I	L	0.0000
54	Y	L	0.0184
55	K	L	-0.4123
56	V	L	0.0000
57	G	L	-0.4019
58	N	L	-0.5398
59	R	L	-0.8287
60	L	L	0.0214
61	S	L	-0.2610
62	G	L	-0.4587
63	V	L	0.1508
64	P	L	-0.3932
65	D	L	-1.8496
66	R	L	-0.5624
67	F	L	0.0000
68	S	L	-0.1337
69	G	L	-0.1550
70	S	L	-0.2397
71	G	L	-0.3448
72	S	L	-0.2791
73	G	L	-0.1523
74	S	L	-0.3511
75	D	L	-1.5320
76	F	L	0.0000
77	T	L	-0.0249
78	L	L	0.0000
79	K	L	-1.5444
80	I	L	0.0000
81	S	L	0.0465
82	W	L	0.8927
83	V	L	0.0000
84	E	L	-1.2876
85	A	L	-0.5566
86	E	L	-1.8172
87	D	L	0.0000
88	V	L	0.5967
89	G	L	0.0000
90	V	L	0.1724
91	Y	L	0.0000
92	Y	L	0.0000
93	C	L	0.0000
94	F	L	0.0000
95	Q	L	0.0000
96	S	L	-0.0269
97	T	L	0.0000
98	H	L	-0.5189
99	I	L	1.5616
100	P	L	0.4545
101	P	L	0.0000
102	T	L	0.0253
103	F	L	0.1863
104	G	L	0.0000
105	G	L	-0.4779
106	G	L	-0.1486
107	T	L	0.0000
108	K	L	-0.8982
109	L	L	0.0000
110	E	L	-1.3997
111	I	L	-0.2676
112	K	L	-1.9890
113	R	L	-2.1541
114	T	L	-0.0841
115	V	L	1.7598
116	E	H	-1.7606
117	V	H	-0.2900
118	Q	H	-1.1021
119	L	H	0.0000
120	L	H	1.2346
121	E	H	0.0000
122	S	H	-0.2619
123	G	H	-0.5243
124	G	H	-0.2542
125	G	H	0.0962
126	L	H	1.5541
127	V	H	0.2760
128	Q	H	-1.1903
129	P	H	-0.4163
130	G	H	-0.5122
131	G	H	-0.3306
132	S	H	-0.1944
133	L	H	-0.1021
134	R	H	-1.8195
135	L	H	0.0000
136	S	H	-0.0248
137	C	H	0.0000
138	A	H	0.1740
139	A	H	0.0000
140	S	H	-0.2267
141	G	H	-0.3935
142	F	H	0.1755
143	T	H	-0.0187
144	F	H	0.0000
145	T	H	-0.2653
146	N	H	-1.1746
147	Y	H	0.0000
148	A	H	0.0039
149	M	H	0.0000
150	S	H	0.0000
151	W	H	0.0000
152	V	H	0.0000
153	R	H	0.0000
154	Q	H	-0.1064
155	A	H	-0.0610
156	P	H	-0.3389
157	G	H	-0.8254
158	K	H	-1.8512
159	G	H	-0.6402
160	L	H	-0.1439
161	E	H	-1.1581
162	W	H	0.0000
163	V	H	0.0000
164	S	H	0.0000
165	S	H	-0.0228
166	I	H	0.0000
167	S	H	-0.0658
168	T	H	-0.1599
169	G	H	-0.5397
170	G	H	-0.4566
171	S	H	-0.2779
172	T	H	0.2304
173	F	H	1.4941
174	Y	H	0.4503
175	A	H	-0.2898
176	D	H	-1.8272
177	S	H	-0.5408
178	V	H	0.0000
179	K	H	-1.7853
180	G	H	-0.8367
181	R	H	-0.4118
182	F	H	0.0000
183	T	H	-0.0692
184	I	H	0.0000
185	S	H	-0.1484
186	R	H	-0.3421
187	D	H	-0.6325
188	N	H	-1.3535
189	S	H	-0.7343
190	K	H	-1.8389
191	N	H	-1.0020
192	T	H	-0.1069
193	L	H	0.0000
194	Y	H	0.2763
195	L	H	0.0000
196	Q	H	-0.4352
197	M	H	0.0000
198	N	H	-0.5462
199	S	H	-0.2326
200	L	H	0.0000
201	R	H	-1.2699
202	A	H	-0.5004
203	E	H	-1.8094
204	D	H	0.0000
205	T	H	-0.0154
206	A	H	0.0000
207	V	H	0.2890
208	Y	H	0.0000
209	Y	H	0.0000
210	C	H	0.0000
211	V	H	0.0000
212	R	H	0.0000
213	G	H	-0.0486
214	L	H	0.0000
215	G	H	0.2724
216	V	H	1.5843
217	H	H	-0.5640
218	Y	H	0.7452
219	F	H	2.0446
220	G	H	0.0000
221	Y	H	0.1680
222	S	H	0.0000
223	V	H	0.0000
224	M	H	0.0000
225	D	H	0.0000
226	Y	H	0.2405
227	W	H	0.1678
228	G	H	0.0000
229	Q	H	-1.2117
230	G	H	-0.2928
231	T	H	-0.0347
232	T	H	-0.0261
233	V	H	0.0000
234	T	H	0.1580
235	V	H	0.0000
236	S	H	-0.1925
237	S	H	-0.2411