Project name: 5vzy:H

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYGMSWVRQAPGKGLELVASINSNGGSTYYPDSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCASGDYWGQGTTVTVSSASTKGPSVFPLAPGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8147
• Maximal score value: 2.3266
• Average score: -0.5825
• Total score value: -119.9903

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.9533
2	V	H	-0.9737
3	Q	H	-0.9259
4	L	H	0.0000
5	V	H	0.3909
6	E	H	0.0000
7	S	H	-0.4686
8	G	H	-0.8431
9	G	H	-0.5056
10	G	H	0.1062
11	L	H	0.4867
12	V	H	0.0000
13	Q	H	-1.5055
14	P	H	-1.5008
15	G	H	-1.4942
16	G	H	-1.1301
17	S	H	-1.2020
18	L	H	-1.1295
19	R	H	-1.9345
20	L	H	0.0000
21	S	H	-0.4814
22	C	H	0.0000
23	A	H	-0.2762
24	A	H	0.0000
25	S	H	-0.9245
26	G	H	-1.0460
27	F	H	-0.1713
28	T	H	0.0391
29	F	H	0.0000
30	S	H	-0.7518
31	S	H	-0.2004
32	Y	H	0.3539
33	G	H	-0.6328
34	M	H	0.0000
35	S	H	0.0409
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.5391
40	A	H	-1.1211
41	P	H	-1.1058
42	G	H	-1.4154
43	K	H	-2.1067
44	G	H	-0.9272
45	L	H	0.5636
46	E	H	-0.2724
47	L	H	0.6203
48	V	H	0.0000
49	A	H	0.0000
50	S	H	0.1908
51	I	H	0.0000
52	N	H	-1.3848
52A	S	H	-1.2282
53	N	H	-2.0333
54	G	H	-1.8212
55	G	H	-1.4522
56	S	H	-0.7405
57	T	H	0.1025
58	Y	H	0.8118
59	Y	H	-0.3059
60	P	H	-1.1160
61	D	H	-2.4288
62	S	H	-1.7842
63	V	H	0.0000
64	K	H	-2.4851
65	G	H	-1.8497
66	R	H	-1.6104
67	F	H	0.0000
68	T	H	-0.7143
69	I	H	0.0000
70	S	H	-0.7291
71	R	H	-1.4978
72	D	H	-1.8875
73	N	H	-1.8897
74	A	H	-1.4550
75	K	H	-2.3337
76	N	H	-1.8250
77	S	H	0.0000
78	L	H	0.0000
79	Y	H	-0.5522
80	L	H	0.0000
81	Q	H	-1.1216
82	M	H	0.0000
82A	N	H	-1.5358
82B	S	H	-1.3593
82C	L	H	0.0000
83	R	H	-2.3795
84	A	H	-1.7614
85	E	H	-2.2269
86	D	H	0.0000
87	T	H	-0.7808
88	A	H	0.0000
89	V	H	0.2588
90	Y	H	0.0000
91	Y	H	0.4008
92	C	H	0.0000
93	A	H	0.0000
94	S	H	-0.3162
95	G	H	-0.8975
101	D	H	-1.4407
102	Y	H	0.0598
103	W	H	0.3673
104	G	H	0.0341
105	Q	H	-0.9180
106	G	H	-0.3095
107	T	H	-0.2440
108	T	H	-0.0701
109	V	H	0.0000
110	T	H	-0.4279
111	V	H	0.0000
112	S	H	-0.6556
113	S	H	-0.6791
114	A	H	-0.4159
115	S	H	-0.3846
116	T	H	-0.8521
117	K	H	-1.1137
118	G	H	-1.3634
119	P	H	0.0000
120	S	H	-0.1151
121	V	H	0.0000
122	F	H	0.9711
123	P	H	0.0961
124	L	H	0.4989
125	A	H	-0.6792
126	P	H	-0.5667
134	G	H	-0.6323
135	T	H	-0.4394
136	A	H	-0.2209
137	A	H	0.0681
138	L	H	0.0000
139	G	H	0.0000
140	C	H	0.0000
141	L	H	0.7134
142	V	H	0.0000
143	K	H	-0.1519
144	D	H	-0.3196
145	Y	H	0.0000
146	F	H	0.0000
147	P	H	-0.7476
148	E	H	-1.0798
149	P	H	-1.2075
150	V	H	-0.6577
151	T	H	-0.6256
152	V	H	-0.3686
153	S	H	-0.3598
154	W	H	0.0000
155	N	H	-0.7709
156	S	H	-0.6985
157	G	H	-0.5827
158	A	H	-0.2649
159	L	H	-0.0508
160	T	H	-0.3219
161	S	H	-0.3861
162	G	H	-0.4948
163	V	H	-0.0620
164	H	H	-0.5959
165	T	H	-0.0339
166	F	H	0.6319
167	P	H	0.3877
168	A	H	1.0453
169	V	H	2.3266
170	L	H	2.1236
171	Q	H	0.7483
172	S	H	0.1199
173	S	H	-0.1579
174	G	H	0.2575
175	L	H	0.2399
176	Y	H	0.7032
177	S	H	0.0000
178	L	H	0.0000
179	S	H	0.5760
180	S	H	0.0000
181	V	H	0.3910
182	V	H	0.0000
183	T	H	-0.2323
184	V	H	0.0000
185	P	H	-0.4592
186	S	H	-0.4485
187	S	H	-0.5751
188	S	H	-0.6043
189	L	H	-0.6296
190	G	H	-0.9781
191	T	H	-0.8063
192	Q	H	-1.4368
193	T	H	-1.2012
194	Y	H	0.0000
195	I	H	-1.4894
196	C	H	0.0000
197	N	H	-1.5472
198	V	H	0.0000
199	N	H	-1.8679
200	H	H	0.0000
201	K	H	-2.8147
202	P	H	-1.7452
203	S	H	-1.8099
204	N	H	-2.6183
205	T	H	-2.0508
206	K	H	-2.7339
207	V	H	-1.8130
208	D	H	-2.7673
209	K	H	-2.3043
210	K	H	-2.5014
211	V	H	0.0000
212	E	H	-2.7566
213	P	H	-1.8564
214	K	H	-2.1595