Project name: 1QPV cofilin

Chain sequence(s)	A: VAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVSR
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.2381
• Maximal score value: 1.3729
• Average score: -1.1699
• Total score value: -155.5981

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
6	V	A	1.3729
7	A	A	0.4735
8	V	A	-0.0740
9	A	A	0.0000
10	D	A	-2.4850
11	E	A	-2.4744
12	S	A	0.0000
13	L	A	-1.0671
14	T	A	-1.4798
15	A	A	0.0000
16	F	A	0.0000
17	N	A	-1.7129
18	D	A	-1.7132
19	L	A	0.0000
20	K	A	-1.3575
21	L	A	-0.0303
22	G	A	-1.5091
23	K	A	-2.4982
24	K	A	-2.6211
25	Y	A	-1.7415
26	K	A	-1.5868
27	F	A	0.0000
28	I	A	0.0000
29	L	A	0.0000
30	F	A	0.0000
31	G	A	0.0000
32	L	A	0.0000
33	N	A	-1.6730
34	D	A	-2.2610
35	A	A	-1.5814
36	K	A	-1.5643
37	T	A	-0.3797
38	E	A	-0.6939
39	I	A	0.0000
40	V	A	-0.9010
41	V	A	-1.0752
42	K	A	-1.7890
43	E	A	-2.1072
44	T	A	-1.3300
45	S	A	-1.2000
46	T	A	-1.4654
47	D	A	-1.9301
48	P	A	-1.5259
49	S	A	-1.2267
50	Y	A	-1.3760
51	D	A	-2.3002
52	A	A	-1.9584
53	F	A	0.0000
54	L	A	-1.3860
55	E	A	-2.7286
56	K	A	-2.2901
57	L	A	0.0000
58	P	A	-2.1771
59	E	A	-3.3061
60	N	A	-2.9661
61	D	A	-2.1947
62	C	A	0.0000
63	L	A	0.0000
64	Y	A	0.0000
65	A	A	0.0000
66	I	A	0.0000
67	Y	A	0.0000
68	D	A	0.0000
69	F	A	0.0000
70	E	A	-2.9992
71	Y	A	0.0000
72	E	A	-3.8955
73	I	A	-2.9121
74	N	A	-3.0887
75	G	A	-2.3426
76	N	A	-3.3788
77	E	A	-3.8634
78	G	A	-3.3267
79	K	A	-4.2381
80	R	A	-3.6929
81	S	A	-2.4478
82	K	A	-1.3680
83	I	A	0.0000
84	V	A	0.0000
85	F	A	0.0000
86	F	A	0.0000
87	T	A	0.0000
88	W	A	0.0000
89	S	A	-1.1715
90	P	A	0.0000
91	D	A	-2.3741
92	T	A	-1.8477
93	A	A	0.0000
94	P	A	-0.5364
95	V	A	0.6727
96	R	A	-0.7060
97	S	A	-0.3352
98	K	A	0.0153
99	M	A	0.9321
100	V	A	0.6123
101	Y	A	0.0000
102	A	A	0.0534
103	S	A	-0.0451
104	S	A	0.0000
105	K	A	-1.0688
106	D	A	-2.0480
107	A	A	-0.9855
108	L	A	0.0000
109	R	A	-2.0799
110	R	A	-2.6638
111	A	A	-1.3768
112	L	A	0.0000
113	N	A	-1.9846
114	G	A	-1.5049
115	V	A	-1.0920
116	S	A	-0.7249
117	T	A	-0.9986
118	D	A	-1.4705
119	V	A	0.0000
120	Q	A	-1.8664
121	G	A	0.0000
122	T	A	-1.5136
123	D	A	-1.9995
124	F	A	-0.6040
125	S	A	-1.1933
126	E	A	-2.3728
127	V	A	0.0000
128	S	A	-0.8877
129	Y	A	-0.9670
130	D	A	-2.3291
131	S	A	-2.0599
132	V	A	0.0000
133	L	A	-2.0303
134	E	A	-3.2674
135	R	A	-3.4121
136	V	A	0.0000
137	S	A	-2.0827
138	R	A	-2.8384