| Chain sequence(s) |
C: GTCVAARTRPVLSY B: KPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 32 | K | B | -2.4237 | |
| 33 | P | B | 0.0000 | |
| 34 | N | B | -2.1255 | |
| 35 | Y | B | 0.0000 | |
| 36 | A | B | -0.6710 | |
| 37 | L | B | -0.2221 | |
| 38 | K | B | -1.0465 | |
| 39 | F | B | -0.2296 | |
| 40 | T | B | -0.2056 | |
| 41 | L | B | 0.0000 | |
| 42 | A | B | 0.0071 | |
| 43 | G | B | -0.2801 | |
| 44 | H | B | 0.0000 | |
| 45 | T | B | -0.6205 | |
| 46 | K | B | -1.0763 | |
| 47 | A | B | 0.0000 | |
| 48 | V | B | 0.0000 | |
| 49 | S | B | 0.0000 | |
| 50 | S | B | 0.0000 | |
| 51 | V | B | 0.0000 | |
| 52 | K | B | -0.2114 | |
| 53 | F | B | 0.0000 | |
| 54 | S | B | 0.0000 | |
| 55 | P | B | -1.5424 | |
| 56 | N | B | -2.2078 | |
| 57 | G | B | 0.0000 | |
| 58 | E | B | -1.5771 | |
| 59 | W | B | -0.8511 | |
| 60 | L | B | 0.0000 | |
| 61 | A | B | 0.0000 | |
| 62 | S | B | 0.0000 | |
| 63 | S | B | 0.0000 | |
| 64 | S | B | 0.0000 | |
| 65 | A | B | 0.0000 | |
| 66 | D | B | 0.0000 | |
| 67 | K | B | -0.4910 | |
| 68 | L | B | -0.0189 | |
| 69 | I | B | 0.0000 | |
| 70 | K | B | 0.0000 | |
| 71 | I | B | 0.0000 | |
| 72 | W | B | 0.0000 | |
| 73 | G | B | 0.0000 | |
| 74 | A | B | 0.0000 | |
| 75 | Y | B | -0.3314 | |
| 76 | D | B | -0.8818 | |
| 77 | G | B | -0.7725 | |
| 78 | K | B | -1.3773 | |
| 79 | F | B | -0.2452 | |
| 80 | E | B | -1.3467 | |
| 81 | K | B | -0.9828 | |
| 82 | T | B | -0.3489 | |
| 83 | I | B | 0.0000 | |
| 84 | S | B | -0.8413 | |
| 85 | G | B | -1.1647 | |
| 86 | H | B | 0.0000 | |
| 87 | K | B | -1.8699 | |
| 88 | L | B | -0.6768 | |
| 89 | G | B | 0.0000 | |
| 90 | I | B | 0.0000 | |
| 91 | S | B | 0.0000 | |
| 92 | D | B | 0.0000 | |
| 93 | V | B | 0.0000 | |
| 94 | A | B | 0.0000 | |
| 95 | W | B | 0.0000 | |
| 96 | S | B | 0.0000 | |
| 97 | S | B | -1.7238 | |
| 98 | D | B | -2.5298 | |
| 99 | S | B | 0.0000 | |
| 100 | N | B | -1.5329 | |
| 101 | L | B | -0.7281 | |
| 102 | L | B | 0.0000 | |
| 103 | V | B | 0.0000 | |
| 104 | S | B | 0.0000 | |
| 105 | A | B | 0.0000 | |
| 106 | S | B | 0.0000 | |
| 107 | D | B | 0.0000 | |
| 108 | D | B | -1.2071 | |
| 109 | K | B | -1.6808 | |
| 110 | T | B | 0.0000 | |
| 111 | L | B | 0.0000 | |
| 112 | K | B | -0.7209 | |
| 113 | I | B | 0.0000 | |
| 114 | W | B | 0.0000 | |
| 115 | D | B | -0.9412 | |
| 116 | V | B | 0.0000 | |
| 117 | S | B | -0.8625 | |
| 118 | S | B | -1.0295 | |
| 119 | G | B | -1.1582 | |
| 120 | K | B | -1.7999 | |
| 121 | C | B | -0.7337 | |
| 122 | L | B | -0.4363 | |
| 123 | K | B | -1.3118 | |
| 124 | T | B | -0.9978 | |
| 125 | L | B | 0.0000 | |
| 126 | K | B | -2.4534 | |
| 127 | G | B | -1.6244 | |
| 128 | H | B | 0.0000 | |
| 129 | S | B | -1.0484 | |
| 130 | N | B | -0.7931 | |
| 131 | Y | B | -0.1511 | |
| 132 | V | B | 0.0000 | |
| 133 | F | B | 0.0000 | |
| 134 | C | B | 0.0000 | |
| 135 | C | B | 0.0000 | |
| 136 | N | B | -0.2834 | |
| 137 | F | B | 0.0000 | |
| 138 | N | B | 0.0000 | |
| 139 | P | B | -1.9480 | |
| 140 | Q | B | -2.1119 | |
| 141 | S | B | -1.3260 | |
| 142 | N | B | -1.1588 | |
| 143 | L | B | -0.5212 | |
| 144 | I | B | 0.0000 | |
| 145 | V | B | 0.0000 | |
| 146 | S | B | 0.0000 | |
| 147 | G | B | 0.0000 | |
| 148 | S | B | 0.0000 | |
| 149 | F | B | -0.3771 | |
| 150 | D | B | -1.0208 | |
| 151 | E | B | -1.4042 | |
| 152 | S | B | 0.0000 | |
| 153 | V | B | 0.0000 | |
| 154 | R | B | -0.3861 | |
| 155 | I | B | 0.0000 | |
| 156 | W | B | 0.0000 | |
| 157 | D | B | -1.1924 | |
| 158 | V | B | 0.0000 | |
| 159 | K | B | -2.1744 | |
| 160 | T | B | -1.5933 | |
| 161 | G | B | -1.6781 | |
| 162 | K | B | -2.1264 | |
| 163 | C | B | -0.7509 | |
| 164 | L | B | 0.1966 | |
| 165 | K | B | -0.4566 | |
| 166 | T | B | -0.3094 | |
| 167 | L | B | 0.0000 | |
| 168 | P | B | -0.5892 | |
| 169 | A | B | 0.0000 | |
| 170 | H | B | 0.0000 | |
| 171 | S | B | -0.9635 | |
| 172 | D | B | -1.2758 | |
| 173 | P | B | -0.7242 | |
| 174 | V | B | 0.0000 | |
| 175 | S | B | 0.0000 | |
| 176 | A | B | 0.0000 | |
| 177 | V | B | 0.0000 | |
| 178 | H | B | -0.5110 | |
| 179 | F | B | 0.0000 | |
| 180 | N | B | -1.9932 | |
| 181 | R | B | -3.3958 | |
| 182 | D | B | -2.9747 | |
| 183 | G | B | -1.8369 | |
| 184 | S | B | -1.0432 | |
| 185 | L | B | -0.5810 | |
| 186 | I | B | 0.0000 | |
| 187 | V | B | 0.0000 | |
| 188 | S | B | 0.0000 | |
| 189 | S | B | 0.0000 | |
| 190 | S | B | 0.0000 | |
| 191 | Y | B | -0.4420 | |
| 192 | D | B | -0.8966 | |
| 193 | G | B | 0.0000 | |
| 194 | L | B | -0.1062 | |
| 195 | C | B | 0.0000 | |
| 196 | R | B | 0.0714 | |
| 197 | I | B | 0.0000 | |
| 198 | W | B | 0.0000 | |
| 199 | D | B | -0.4441 | |
| 200 | T | B | -0.4282 | |
| 201 | A | B | -0.3857 | |
| 202 | S | B | -0.6640 | |
| 203 | G | B | -0.6382 | |
| 204 | Q | B | -0.9111 | |
| 205 | C | B | 0.0022 | |
| 206 | L | B | 0.6527 | |
| 207 | K | B | -0.1082 | |
| 208 | T | B | 0.2763 | |
| 209 | L | B | 0.0000 | |
| 210 | I | B | 0.5885 | |
| 211 | D | B | -1.3547 | |
| 214 | N | B | -1.4445 | |
| 215 | P | B | -1.3772 | |
| 216 | P | B | -0.9732 | |
| 217 | V | B | 0.0000 | |
| 218 | S | B | 0.0000 | |
| 219 | F | B | 0.0000 | |
| 220 | V | B | 0.0000 | |
| 221 | K | B | -0.3343 | |
| 222 | F | B | 0.0000 | |
| 223 | S | B | 0.0000 | |
| 224 | P | B | -1.2798 | |
| 225 | N | B | -2.1152 | |
| 226 | G | B | -2.2484 | |
| 227 | K | B | -2.2883 | |
| 228 | Y | B | -0.8027 | |
| 229 | I | B | 0.0000 | |
| 230 | L | B | 0.0000 | |
| 231 | A | B | 0.0000 | |
| 232 | A | B | 0.0000 | |
| 233 | T | B | 0.0000 | |
| 234 | L | B | 0.0000 | |
| 235 | D | B | -2.3552 | |
| 236 | N | B | -1.9996 | |
| 237 | T | B | -1.0783 | |
| 238 | L | B | 0.0000 | |
| 239 | K | B | -0.0690 | |
| 240 | L | B | 0.0000 | |
| 241 | W | B | 0.0000 | |
| 242 | D | B | -1.3569 | |
| 243 | Y | B | -1.2192 | |
| 244 | S | B | -1.4807 | |
| 245 | K | B | -2.4102 | |
| 246 | G | B | -1.6112 | |
| 247 | K | B | -2.0406 | |
| 248 | C | B | -0.5914 | |
| 249 | L | B | 0.1951 | |
| 250 | K | B | -0.5762 | |
| 251 | T | B | -0.2716 | |
| 252 | Y | B | 0.0000 | |
| 253 | T | B | -0.9386 | |
| 254 | G | B | -0.8630 | |
| 255 | H | B | 0.0000 | |
| 256 | K | B | -2.2969 | |
| 257 | N | B | 0.0000 | |
| 258 | E | B | -3.0061 | |
| 259 | K | B | -2.2267 | |
| 260 | Y | B | -1.2877 | |
| 261 | C | B | 0.0000 | |
| 262 | I | B | 0.0000 | |
| 263 | F | B | 0.0000 | |
| 264 | A | B | 0.0000 | |
| 265 | N | B | -0.0337 | |
| 266 | F | B | 0.0000 | |
| 267 | S | B | 0.0000 | |
| 268 | V | B | 0.3268 | |
| 269 | T | B | -0.1721 | |
| 270 | G | B | -0.7933 | |
| 271 | G | B | -1.0709 | |
| 272 | K | B | -1.4303 | |
| 273 | W | B | 0.0000 | |
| 274 | I | B | 0.0000 | |
| 275 | V | B | 0.0000 | |
| 276 | S | B | 0.0000 | |
| 277 | G | B | 0.0000 | |
| 278 | S | B | 0.0000 | |
| 279 | E | B | 0.0000 | |
| 280 | D | B | -1.3263 | |
| 281 | N | B | -1.4841 | |
| 282 | L | B | 0.0000 | |
| 283 | V | B | 0.0000 | |
| 284 | Y | B | 0.0000 | |
| 285 | I | B | 0.0000 | |
| 286 | W | B | 0.0000 | |
| 287 | N | B | -1.9600 | |
| 288 | L | B | 0.0000 | |
| 289 | Q | B | -2.0347 | |
| 290 | T | B | -1.6290 | |
| 291 | K | B | -2.0588 | |
| 292 | E | B | -2.3395 | |
| 293 | I | B | -0.9513 | |
| 294 | V | B | 0.0000 | |
| 295 | Q | B | -1.6657 | |
| 296 | K | B | -2.0526 | |
| 297 | L | B | 0.0000 | |
| 298 | Q | B | -1.8242 | |
| 299 | G | B | -1.0671 | |
| 300 | H | B | 0.0000 | |
| 301 | T | B | -1.1137 | |
| 302 | D | B | -1.2117 | |
| 303 | V | B | 0.0000 | |
| 304 | V | B | 0.0000 | |
| 305 | I | B | 0.0000 | |
| 306 | S | B | 0.0000 | |
| 307 | T | B | 0.0000 | |
| 308 | A | B | 0.0000 | |
| 309 | C | B | 0.0027 | |
| 310 | H | B | 0.0000 | |
| 311 | P | B | -0.6634 | |
| 312 | T | B | -0.7090 | |
| 313 | E | B | -1.1507 | |
| 314 | N | B | -1.1190 | |
| 315 | I | B | 0.0000 | |
| 316 | I | B | 0.0000 | |
| 317 | A | B | 0.0000 | |
| 318 | S | B | 0.0000 | |
| 319 | A | B | 0.0000 | |
| 320 | A | B | 0.0000 | |
| 321 | L | B | 0.0000 | |
| 322 | E | B | -1.8690 | |
| 323 | N | B | -1.9486 | |
| 324 | D | B | -1.4958 | |
| 325 | K | B | -1.3325 | |
| 326 | T | B | -0.7198 | |
| 327 | I | B | 0.0000 | |
| 328 | K | B | 0.0000 | |
| 329 | L | B | 0.0000 | |
| 330 | W | B | 0.0000 | |
| 331 | K | B | -1.1168 | |
| 332 | S | B | -1.8538 | |
| 333 | D | B | -2.4066 | |
| 334 | C | B | -1.5211 | |
| 586 | G | C | -0.2126 | |
| 587 | T | C | -0.2753 | |
| 588 | C | C | 0.1495 | |
| 589 | V | C | 0.1037 | |
| 590 | A | C | 0.0000 | |
| 591 | A | C | -0.2335 | |
| 592 | R | C | 0.0000 | |
| 593 | T | C | 0.0000 | |
| 594 | R | C | -1.7246 | |
| 595 | P | C | -1.0738 | |
| 596 | V | C | 0.0932 | |
| 597 | L | C | 1.4787 | |
| 598 | S | C | 1.1205 | |
| 599 | Y | C | 1.6386 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine