Project name: 5u5f:B

Chain sequence(s)	B: EVQLVESGGGLVQPGGSLRLSSSCAASGFNNIKDTYIHWVRQSPGKGLEWVARIYPTNGYTRRYADSVKKGRFTISADTSKKNTAYLQMNSLRAEDTAIYYCCSRWGGDGFYAMDYWGQGTLVTVSSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTTVPSSSLGTQTYICNVNNHKPSNTKKVDKKVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8884
• Maximal score value: 2.5578
• Average score: -0.5739
• Total score value: -127.9688

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	B	-2.0751
2	V	B	-1.2942
3	Q	B	-1.0279
4	L	B	0.0000
5	V	B	0.4993
6	E	B	0.0000
7	S	B	-0.5291
8	G	B	-0.9235
9	G	B	-0.4015
10	G	B	-0.4658
11	L	B	-0.1023
12	V	B	0.0000
13	Q	B	-1.6768
14	P	B	-1.7827
15	G	B	-1.4768
16	G	B	-1.1832
17	S	B	-1.1640
18	L	B	-1.1519
19	R	B	-2.0615
20	L	B	0.0000
21	S	B	-0.4285
22	C	B	0.0000
23	A	B	-0.2201
24	A	B	0.0000
25	S	B	-1.1790
26	G	B	-1.4180
27	F	B	-1.5823
28	N	B	-2.1792
29	I	B	0.0000
30	K	B	-2.4585
31	D	B	-2.7677
32	T	B	0.0000
33	Y	B	0.0247
34	I	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.3106
40	S	B	-0.9877
41	P	B	-1.0979
42	G	B	-1.7222
43	K	B	-2.1876
44	G	B	-0.7040
45	L	B	0.6481
46	E	B	-0.1240
47	W	B	0.2759
48	V	B	0.0000
49	A	B	0.0000
50	R	B	-1.1036
51	I	B	0.0000
52	Y	B	-0.4414
53	P	B	-1.0367
54	T	B	-1.0686
55	N	B	-0.8601
56	G	B	-0.3346
57	Y	B	0.4081
58	T	B	-0.6610
59	R	B	-2.1916
60	Y	B	-1.9531
61	A	B	-1.8136
62	D	B	-2.6816
63	S	B	-1.8354
64	V	B	0.0000
65	K	B	-2.8884
66	G	B	-1.7978
67	R	B	-1.4184
68	F	B	0.0000
69	T	B	-1.1416
70	I	B	0.0000
71	S	B	-0.1716
72	A	B	-0.7099
73	D	B	-1.3176
74	T	B	-1.5106
75	S	B	-1.5169
76	K	B	-2.2123
77	N	B	-1.7378
78	T	B	-0.8874
79	A	B	0.0000
80	Y	B	-0.4111
81	L	B	0.0000
82	Q	B	-1.0938
83	M	B	0.0000
84	N	B	-1.4487
85	S	B	-1.2899
86	L	B	0.0000
87	R	B	-2.4458
88	A	B	-1.7896
89	E	B	-2.6461
90	D	B	0.0000
91	T	B	-0.8116
92	A	B	0.0000
93	I	B	0.6165
94	Y	B	0.0000
95	Y	B	0.4112
96	C	B	0.0000
97	S	B	0.0000
98	R	B	0.0000
99	W	B	0.6406
100	G	B	0.3729
101	G	B	0.0000
102	D	B	-1.5174
103	G	B	-0.2159
104	F	B	1.7529
105	Y	B	1.9460
106	A	B	1.2826
107	M	B	0.9313
108	D	B	0.2831
109	Y	B	0.2788
110	W	B	0.3733
111	G	B	-0.1142
112	Q	B	-0.8089
113	G	B	-0.1580
114	T	B	0.0435
115	L	B	0.2421
116	V	B	0.0000
117	T	B	-0.4184
118	V	B	0.0000
119	S	B	-0.8008
120	S	B	-0.7312
121	A	B	-0.4804
122	S	B	-0.6183
123	T	B	-0.7331
124	K	B	-1.4447
125	G	B	-1.6169
126	P	B	-0.6565
127	S	B	-0.1031
128	V	B	0.0000
129	F	B	1.1945
130	P	B	0.0845
131	L	B	0.4267
132	A	B	-0.9748
133	P	B	0.0000
134	S	B	-1.2753
135	S	B	-1.1524
136	K	B	-1.8959
137	S	B	-0.9924
138	T	B	-1.0021
139	S	B	-0.9535
140	G	B	-0.8578
141	G	B	-0.9185
142	T	B	-0.6342
143	A	B	0.0000
144	A	B	-0.1996
145	L	B	0.0000
146	G	B	0.0000
147	C	B	0.0000
148	L	B	0.8306
149	V	B	0.0000
150	K	B	-0.1850
151	D	B	-0.6390
152	Y	B	0.0000
153	F	B	0.0000
154	P	B	0.0000
155	E	B	-0.5430
156	P	B	-0.6860
157	V	B	-0.6406
158	T	B	-0.5549
159	V	B	-0.1272
160	S	B	-0.3581
161	W	B	0.0000
162	N	B	-0.7849
163	S	B	-0.6496
164	G	B	-0.5171
165	A	B	-0.2399
166	L	B	-0.0247
167	T	B	-0.3028
168	S	B	-0.3723
169	G	B	-0.4908
170	V	B	-0.0535
171	H	B	-0.5840
172	T	B	0.0702
173	F	B	0.8466
174	P	B	0.7110
175	A	B	1.3276
176	V	B	2.5578
177	L	B	2.2451
178	Q	B	0.7234
179	S	B	0.1108
180	S	B	-0.2004
181	G	B	0.2386
182	L	B	0.2732
183	Y	B	0.8775
184	S	B	0.0000
185	L	B	0.9595
186	S	B	0.7022
187	S	B	0.0000
188	V	B	0.3441
189	V	B	0.0000
190	T	B	-0.2515
191	V	B	0.0000
192	P	B	-0.6148
193	S	B	-0.5412
194	S	B	-0.5203
195	S	B	-0.4958
196	L	B	-0.6717
197	G	B	-1.0342
198	T	B	-0.6715
199	Q	B	-1.1875
200	T	B	-1.1124
201	Y	B	0.0000
202	I	B	-1.4199
203	C	B	0.0000
204	N	B	-1.4694
205	V	B	0.0000
206	N	B	-2.0450
207	H	B	0.0000
208	K	B	-2.8157
209	P	B	-1.6413
210	S	B	-1.9269
211	N	B	-2.6376
212	T	B	-2.1777
213	K	B	-2.7771
214	V	B	-1.7438
215	D	B	-2.4491
216	K	B	-2.0703
217	K	B	-2.4736
218	V	B	0.0000
219	E	B	-2.8769
220	P	B	-1.8263
221	K	B	-2.1519
222	S	B	-0.9637
223	C	B	0.1834