Project name: 5ggu:H

Chain sequence(s)	H: QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVIWYDGSNKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDPRGATLYYYYYGMDVWGQGTTVTVSSASTKGPSVFPLAPGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9084
• Maximal score value: 3.0393
• Average score: -0.4541
• Total score value: -98.9933

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.1949
2	V	H	-0.3234
3	Q	H	-0.7364
4	L	H	0.0000
5	V	H	0.5652
6	E	H	0.0000
7	S	H	-0.5456
8	G	H	-0.9721
9	G	H	-0.5985
10	G	H	0.0624
11	V	H	0.4369
12	V	H	0.0000
13	Q	H	-1.7390
14	P	H	-1.9517
15	G	H	-2.0178
16	R	H	-2.7306
17	S	H	-2.0975
18	L	H	-1.4383
19	R	H	-2.0396
20	L	H	0.0000
21	S	H	-0.4259
22	C	H	0.0000
23	A	H	-0.2633
24	A	H	0.0000
25	S	H	-0.8064
26	G	H	-0.7430
27	F	H	-0.2328
28	T	H	-0.1098
29	F	H	0.0000
30	S	H	-0.6655
31	S	H	-0.2316
32	Y	H	0.0000
33	G	H	0.0000
34	M	H	0.0000
35	H	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.7180
40	A	H	-1.2651
41	P	H	-0.9800
42	G	H	-1.4619
43	K	H	-2.1566
44	G	H	-1.0193
45	L	H	0.3799
46	E	H	-0.5826
47	W	H	0.0413
48	V	H	0.0000
49	A	H	0.0000
50	V	H	0.0000
51	I	H	0.0000
52	W	H	-0.2542
53	Y	H	-0.1490
54	D	H	-1.6692
55	G	H	-1.2726
56	S	H	-1.0919
57	N	H	-1.2216
58	K	H	-0.6739
59	Y	H	-0.0255
60	Y	H	-0.6200
61	A	H	-1.2244
62	D	H	-2.3849
63	S	H	-1.8400
64	V	H	0.0000
65	K	H	-2.5251
66	G	H	-1.8229
67	R	H	-1.6107
68	F	H	0.0000
69	T	H	-0.8032
70	I	H	0.0000
71	S	H	-0.4881
72	R	H	-1.1028
73	D	H	-1.9514
74	N	H	-2.0363
75	S	H	-1.7472
76	K	H	-2.5705
77	N	H	-2.1250
78	T	H	-1.2102
79	L	H	0.0000
80	Y	H	-0.4169
81	L	H	0.0000
82	Q	H	-1.1352
83	M	H	0.0000
84	N	H	-1.9387
85	S	H	-1.7568
86	L	H	0.0000
87	R	H	-2.3825
88	A	H	-1.6189
89	E	H	-2.1970
90	D	H	0.0000
91	T	H	-0.7451
92	A	H	0.0000
93	V	H	0.0725
94	Y	H	0.0000
95	Y	H	0.2736
96	C	H	0.0000
97	A	H	0.0000
98	R	H	-0.1483
99	D	H	0.0000
100	P	H	0.0000
101	R	H	0.8893
102	G	H	1.6922
103	A	H	1.0722
104	T	H	1.5436
105	L	H	2.4933
106	Y	H	3.0393
107	Y	H	2.9068
108	Y	H	2.8715
109	Y	H	2.3866
110	Y	H	1.7630
111	G	H	0.4813
112	M	H	0.1938
113	D	H	-0.2579
114	V	H	-0.0254
115	W	H	0.1991
116	G	H	-0.1996
117	Q	H	-0.9090
118	G	H	-0.3912
119	T	H	-0.2980
120	T	H	-0.1845
121	V	H	0.0000
122	T	H	-0.3699
123	V	H	0.0000
124	S	H	-0.7111
125	S	H	-0.5270
126	A	H	-0.4015
127	S	H	-0.5101
128	T	H	-0.6306
129	K	H	-1.1803
130	G	H	-1.4691
131	P	H	0.0000
132	S	H	-0.0398
133	V	H	0.0000
134	F	H	0.9662
135	P	H	0.0940
136	L	H	0.3939
137	A	H	-0.4583
138	P	H	-0.4140
146	G	H	-0.6516
147	T	H	-0.4657
148	A	H	-0.2449
149	A	H	0.1044
150	L	H	0.0000
151	G	H	0.0000
152	C	H	0.0000
153	L	H	0.8246
154	V	H	0.0000
155	K	H	-0.1692
156	D	H	-0.5648
157	Y	H	0.0000
158	F	H	0.0000
159	P	H	-0.7412
160	E	H	-1.1037
161	P	H	-1.1810
162	V	H	-0.9468
163	T	H	-0.7240
164	V	H	-0.3093
165	S	H	-0.4221
166	W	H	0.0000
167	N	H	-0.7656
168	S	H	-0.6740
169	G	H	-0.5671
170	A	H	-0.2414
171	L	H	0.0005
172	T	H	-0.2866
173	S	H	-0.3717
174	G	H	-0.4746
175	V	H	0.0106
176	H	H	-0.4339
177	T	H	0.1909
178	F	H	1.0265
179	P	H	0.6291
180	A	H	1.0943
181	V	H	2.3804
182	L	H	1.8584
183	Q	H	0.6299
184	S	H	0.0821
185	S	H	-0.1789
186	G	H	0.2197
187	L	H	0.1724
188	Y	H	0.6255
189	S	H	0.0000
190	L	H	0.0000
191	S	H	0.7080
192	S	H	0.0000
193	V	H	0.4806
194	V	H	0.0000
195	T	H	-0.2339
196	V	H	0.0000
197	P	H	-0.5778
198	S	H	-0.5153
199	S	H	-0.5746
200	S	H	-0.5349
201	L	H	-0.7365
202	G	H	-1.0166
203	T	H	-0.6431
204	Q	H	-1.1019
205	T	H	-1.0685
206	Y	H	0.0000
207	I	H	-1.4031
208	C	H	0.0000
209	N	H	-1.6217
210	V	H	0.0000
211	N	H	-2.2509
212	H	H	0.0000
213	K	H	-2.9084
214	P	H	-1.7864
215	S	H	-1.8936
216	N	H	-2.6392
217	T	H	-2.1793
218	K	H	-2.8142
219	V	H	-1.7979
220	D	H	-2.7433
221	K	H	-2.1369
222	K	H	-2.5772
223	V	H	0.0000
224	E	H	-2.4773
225	P	H	-1.3140