Project name: 5hyq:B

Chain sequence(s)	B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9256
• Maximal score value: 2.376
• Average score: -0.5267
• Total score value: -115.8799

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.4201
2	V	B	-0.7563
3	Q	B	-1.3471
4	L	B	0.0000
5	K	B	-1.9924
6	Q	B	-1.1260
7	S	B	-0.8448
8	G	B	-1.0716
9	P	B	-0.4274
10	G	B	-0.3329
11	L	B	0.1306
12	V	B	-0.5501
13	Q	B	-1.1058
14	P	B	-1.3269
15	S	B	-1.5301
16	Q	B	-1.8668
17	S	B	-1.8430
18	L	B	0.0000
19	S	B	-0.8698
20	I	B	0.0000
21	T	B	-0.5894
22	C	B	0.0000
23	T	B	-1.1005
24	V	B	0.0000
25	S	B	-1.1871
26	G	B	-0.9526
27	F	B	-0.5219
28	S	B	-0.8797
29	L	B	0.0000
30	T	B	-0.8839
31	N	B	-0.8627
32	Y	B	0.4097
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.2859
40	S	B	0.0000
41	P	B	-1.1030
42	G	B	-1.6367
43	K	B	-2.0356
44	G	B	-0.6781
45	L	B	0.7214
46	E	B	0.0659
47	W	B	0.3747
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.5990
53	S	B	-0.6612
54	G	B	-1.2329
55	G	B	-1.5457
56	N	B	-1.9426
57	T	B	-1.4633
58	D	B	-1.4123
59	Y	B	-0.6628
60	N	B	-0.6981
61	T	B	-0.5403
62	P	B	-0.4874
63	F	B	0.0000
64	T	B	-0.6146
65	S	B	-0.7225
66	R	B	-1.3133
67	L	B	0.0000
68	S	B	-1.3045
69	I	B	0.0000
70	N	B	-1.7797
71	K	B	-1.3869
72	D	B	-1.6642
73	N	B	-2.0399
74	S	B	-1.5910
75	K	B	-2.3004
76	S	B	-1.5436
77	Q	B	-1.4481
78	V	B	0.0000
79	F	B	-0.4207
80	F	B	0.0000
81	K	B	-2.0092
82	M	B	0.0000
83	N	B	-2.3828
84	S	B	-1.6692
85	L	B	0.0000
86	Q	B	-2.1514
87	S	B	-1.5126
88	N	B	-2.0968
89	D	B	0.0000
90	T	B	-0.6676
91	A	B	0.0000
92	I	B	0.5321
93	Y	B	0.0000
94	Y	B	-0.0555
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.7971
100	T	B	1.3993
101	Y	B	1.9387
102	Y	B	1.7783
103	D	B	0.8143
104	Y	B	0.7595
105	E	B	0.0182
106	F	B	0.6588
107	A	B	0.8142
108	Y	B	0.6283
109	W	B	0.2062
110	G	B	0.0000
111	Q	B	-1.3940
112	G	B	-0.5604
113	T	B	0.0000
114	L	B	0.4223
115	V	B	0.0000
116	T	B	-0.1936
117	V	B	0.0000
118	S	B	-0.5495
119	A	B	-0.2070
120	A	B	-0.1967
121	S	B	-0.4202
122	T	B	-0.6629
123	K	B	-1.1727
124	G	B	-1.3857
125	P	B	0.0000
126	S	B	-0.0315
127	V	B	0.0000
128	F	B	1.1415
129	P	B	-0.0785
130	L	B	0.3465
131	A	B	-0.9335
132	P	B	0.0000
133	S	B	-1.3786
134	S	B	-1.3246
135	K	B	-1.8880
136	S	B	-1.0005
137	T	B	-0.9979
138	S	B	-0.9713
139	G	B	-0.8409
140	G	B	-0.8944
141	T	B	-0.6433
142	A	B	0.0000
143	A	B	-0.1870
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.7846
148	V	B	0.0000
149	K	B	-0.1415
150	D	B	-0.5960
151	Y	B	0.0000
152	F	B	-0.2127
153	P	B	0.0000
154	E	B	-0.1265
155	P	B	-0.5176
156	V	B	-0.6155
157	T	B	-0.6005
158	V	B	-0.2949
159	S	B	-0.5112
160	W	B	0.0000
161	N	B	-0.9471
162	S	B	-0.7031
163	G	B	-0.5495
164	A	B	-0.2553
165	L	B	-0.0374
166	T	B	-0.2898
167	S	B	-0.2963
168	G	B	-0.3069
169	V	B	-0.0540
170	H	B	-0.5563
171	T	B	0.0956
172	F	B	0.9000
173	P	B	0.6957
174	A	B	1.2411
175	V	B	2.3760
176	L	B	1.9512
177	Q	B	0.5805
178	S	B	0.0398
179	S	B	-0.2383
180	G	B	0.2410
181	L	B	0.3277
182	Y	B	0.8356
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.6507
186	S	B	0.0000
187	V	B	0.3221
188	V	B	0.0000
189	T	B	-0.1932
190	V	B	0.0000
191	P	B	-0.5441
192	S	B	-0.6042
193	S	B	-0.5860
194	S	B	-0.6291
195	L	B	-0.8112
196	G	B	-0.9767
197	T	B	-0.7387
198	Q	B	-1.2539
199	T	B	-1.2260
200	Y	B	0.0000
201	I	B	-1.6057
202	C	B	0.0000
203	N	B	-1.6069
204	V	B	0.0000
205	N	B	-2.0459
206	H	B	0.0000
207	K	B	-2.8234
208	P	B	-1.5142
209	S	B	-1.7926
210	N	B	-2.5813
211	T	B	-2.0864
212	K	B	-2.7857
213	V	B	-1.8607
214	D	B	-2.7364
215	K	B	-2.2273
216	R	B	-2.7198
217	V	B	0.0000
218	E	B	-2.9256
219	P	B	-1.9198
220	K	B	-2.2729