Project name: 4g6m:H

Chain sequence(s)	H: QVQLQESGPGLVKPSQTLSLTCSFSGFSLSTSGMGVGWIRQPSGKGLEWLAHIWWDGDESYNPSLKSRLTISKDTSKNQVSLKITSVTAADTAVYFCARNRYDPPWFVDWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.1958
• Maximal score value: 2.3606
• Average score: -0.5445
• Total score value: -119.7878

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.4757
2	V	H	-0.8971
3	Q	H	-1.7909
4	L	H	0.0000
5	Q	H	-1.3278
6	E	H	0.0000
7	S	H	-0.4572
8	G	H	-0.4005
9	P	H	-0.3321
10	G	H	-0.2667
11	L	H	-0.2727
12	V	H	0.0000
13	K	H	-2.1534
14	P	H	-1.3862
15	S	H	-1.2544
16	Q	H	-1.7187
17	T	H	-1.2326
18	L	H	0.0000
19	S	H	-0.8414
20	L	H	0.0000
21	T	H	-0.6546
22	C	H	0.0000
23	S	H	-1.3132
24	F	H	0.0000
25	S	H	-1.3756
26	G	H	-1.1045
27	F	H	-0.5167
28	S	H	-0.3317
29	L	H	0.0000
30	S	H	-0.7064
31	T	H	-0.4689
32	S	H	-0.4340
33	G	H	0.0000
34	M	H	0.0000
35	G	H	0.0000
36	V	H	0.0000
37	G	H	0.0000
38	W	H	0.0000
39	I	H	0.0000
40	R	H	0.0000
41	Q	H	-0.4133
42	P	H	-0.7395
43	S	H	-1.0412
44	G	H	-1.5539
45	K	H	-2.0622
46	G	H	-0.8992
47	L	H	0.7329
48	E	H	0.0553
49	W	H	0.5055
50	L	H	0.0000
51	A	H	0.0000
52	H	H	0.0000
53	I	H	0.0000
54	W	H	-1.6468
55	W	H	-1.2057
56	D	H	-2.4919
57	G	H	-2.3792
58	D	H	-3.1958
59	E	H	-2.9190
60	S	H	-1.6065
61	Y	H	-1.0284
62	N	H	-0.8287
63	P	H	-1.1445
64	S	H	-0.8798
65	L	H	0.0000
66	K	H	-2.0409
67	S	H	-1.2645
68	R	H	-1.3095
69	L	H	0.0000
70	T	H	-1.1579
71	I	H	0.0000
72	S	H	-1.2825
73	K	H	-1.3783
74	D	H	-1.8496
75	T	H	-1.5188
76	S	H	-1.5837
77	K	H	-2.5779
78	N	H	-2.2238
79	Q	H	-1.8551
80	V	H	0.0000
81	S	H	-0.7904
82	L	H	0.0000
83	K	H	-1.3302
84	I	H	0.0000
85	T	H	-0.9204
86	S	H	-0.9608
87	V	H	0.0000
88	T	H	-0.5614
89	A	H	-0.2406
90	A	H	0.0508
91	D	H	0.0000
92	T	H	0.1152
93	A	H	0.0000
94	V	H	0.4701
95	Y	H	0.0000
96	F	H	0.2419
97	C	H	0.0000
98	A	H	0.0000
99	R	H	0.3029
100	N	H	0.0000
101	R	H	-0.2669
102	Y	H	0.0812
103	D	H	-1.3313
104	P	H	-0.8304
105	P	H	0.1308
106	W	H	1.4320
107	F	H	1.5650
108	V	H	2.0728
109	D	H	0.6433
110	W	H	0.3519
111	G	H	-0.8817
112	Q	H	-1.2500
113	G	H	0.0000
114	T	H	-0.0253
115	L	H	0.5412
116	V	H	0.0000
117	T	H	0.0000
118	V	H	0.0000
119	S	H	-0.7507
120	S	H	-0.8468
121	A	H	-0.5320
122	S	H	-0.6229
123	T	H	-0.7437
124	K	H	-1.2067
125	G	H	-1.4692
126	P	H	0.0000
127	S	H	-0.2747
128	V	H	0.0000
129	F	H	0.9329
130	P	H	0.0021
131	L	H	0.3873
132	A	H	-0.4962
133	P	H	0.0000
134	S	H	-1.0579
135	S	H	-1.2337
136	K	H	-1.9684
137	S	H	-1.2123
138	T	H	-0.9778
139	S	H	-0.9524
140	G	H	-0.8178
141	G	H	-0.6413
142	T	H	-0.4443
143	A	H	0.0000
144	A	H	0.1003
145	L	H	0.0000
146	G	H	0.0000
147	C	H	0.0000
148	L	H	0.7264
149	V	H	0.0000
150	K	H	-0.2654
151	D	H	-0.4577
152	Y	H	0.0000
153	F	H	0.0000
154	P	H	0.0000
155	E	H	-0.3267
156	P	H	-0.5996
157	V	H	-0.6790
158	T	H	-0.6282
159	V	H	-0.2213
160	S	H	-0.3390
161	W	H	0.0000
162	N	H	-0.7944
163	S	H	-0.6448
164	G	H	-0.5639
165	A	H	-0.2425
166	L	H	-0.0381
167	T	H	-0.2874
168	S	H	-0.3631
169	G	H	-0.4574
170	V	H	0.0141
171	H	H	-0.4010
172	T	H	0.2367
173	F	H	0.8828
174	P	H	0.6504
175	A	H	1.2171
176	V	H	2.3606
177	L	H	1.9423
178	Q	H	0.5439
179	S	H	0.0088
180	S	H	-0.2680
181	G	H	0.1618
182	L	H	0.2216
183	Y	H	0.7432
184	S	H	0.0000
185	L	H	0.0000
186	S	H	0.6378
187	S	H	0.0000
188	V	H	0.4247
189	V	H	0.0000
190	T	H	-0.2150
191	V	H	0.0000
192	P	H	-0.5695
193	S	H	-0.6538
194	S	H	-0.7325
195	S	H	-0.6961
196	L	H	-0.9136
197	G	H	-1.0842
198	T	H	-0.7000
199	Q	H	-1.1597
200	T	H	-1.1604
201	Y	H	0.0000
202	I	H	-1.4709
203	C	H	0.0000
204	N	H	-1.4549
205	V	H	0.0000
206	N	H	-2.0639
207	H	H	0.0000
208	K	H	-2.7877
209	P	H	-1.6630
210	S	H	-1.8493
211	N	H	-2.6239
212	T	H	-2.0925
213	K	H	-2.7500
214	V	H	-1.6040
215	D	H	-2.4078
216	K	H	-2.2192
217	R	H	-2.6653
218	V	H	0.0000
219	E	H	-2.5491
220	P	H	-1.1823