Project name: 8c8c2757e03dd14

Chain sequence(s)	A: CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN; B: CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEEIDTKSYWKALGISSPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.3211
• Maximal score value: 1.538
• Average score: -0.6992
• Total score value: -160.8193

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
10	C	A	-0.4914
11	P	A	0.0000
12	L	A	0.0000
13	M	A	-0.5005
14	V	A	0.0000
15	K	A	-0.7898
16	V	A	0.0000
17	L	A	0.5888
18	D	A	0.0000
19	A	A	0.4555
20	V	A	0.8695
21	R	A	-1.1343
22	G	A	-0.6758
23	S	A	-0.5265
24	P	A	-0.6518
25	A	A	0.0000
26	I	A	-0.7022
27	N	A	-1.7998
28	V	A	0.0000
29	A	A	-1.2891
30	V	A	0.0000
31	H	A	-1.0755
32	V	A	0.0000
33	F	A	-0.7719
34	R	A	-1.2623
35	K	A	-1.6357
36	A	A	-1.7935
37	A	A	-1.6770
38	D	A	-2.6580
39	D	A	-2.9260
40	T	A	-1.9487
41	W	A	-1.4124
42	E	A	-2.1157
43	P	A	-1.1459
44	F	A	-0.7257
45	A	A	-0.4840
46	S	A	-0.8245
47	G	A	-1.3804
48	K	A	-2.1839
49	T	A	0.0000
50	S	A	-1.7934
51	E	A	-2.1175
52	S	A	-1.2268
53	G	A	0.0000
54	E	A	-1.4361
55	L	A	0.0000
56	H	A	-1.3880
57	G	A	-0.7952
58	L	A	0.0000
59	T	A	0.0000
60	T	A	-1.8851
61	E	A	-3.3211
62	E	A	-3.2872
63	E	A	-2.9076
64	F	A	0.0000
65	V	A	-1.5741
66	E	A	-2.1903
67	G	A	-1.0505
68	I	A	-0.4441
69	Y	A	0.0000
70	K	A	-0.5253
71	V	A	0.0000
72	E	A	-0.7607
73	I	A	0.0000
74	D	A	-1.4078
75	T	A	0.0000
76	K	A	-1.5791
77	S	A	-1.2644
78	Y	A	0.0000
79	W	A	0.0000
80	K	A	-1.2824
81	A	A	-0.4178
82	L	A	0.2249
83	G	A	-0.3351
84	I	A	-0.1465
85	S	A	-0.4321
86	P	A	-0.4333
87	F	A	0.0000
88	H	A	0.0000
89	E	A	-0.7264
90	H	A	-0.8485
91	A	A	0.0000
92	E	A	0.0000
93	V	A	0.0000
94	V	A	0.0000
95	F	A	0.0000
96	T	A	-0.7528
97	A	A	0.0000
98	N	A	0.0000
99	D	A	-2.4814
100	S	A	-1.5941
101	G	A	-1.5266
102	P	A	-2.4586
103	R	A	-2.7263
104	R	A	-2.3569
105	Y	A	0.0000
106	T	A	-0.0349
107	I	A	0.0000
108	A	A	0.1618
109	A	A	0.0000
110	L	A	0.8351
111	L	A	0.0000
112	S	A	0.5808
113	P	A	0.3306
114	Y	A	0.9018
115	S	A	0.5092
116	Y	A	0.0000
117	S	A	0.2175
118	T	A	0.0000
119	T	A	0.5091
120	A	A	0.0000
121	V	A	1.5380
122	V	A	0.0972
123	T	A	-1.0101
124	N	A	-2.0673
10	C	B	-0.7982
11	P	B	0.0000
12	L	B	0.0000
13	M	B	-0.5220
14	V	B	0.0000
15	K	B	-0.4626
16	V	B	0.0000
17	L	B	0.4993
18	D	B	0.0000
19	A	B	0.4295
20	V	B	0.8009
21	R	B	-1.1102
22	G	B	-0.7660
23	S	B	-0.5912
24	P	B	-0.6945
25	A	B	0.0000
26	I	B	-1.0312
27	N	B	-2.0809
28	V	B	0.0000
29	A	B	-1.4560
30	V	B	0.0000
31	H	B	-1.1280
32	V	B	0.0000
33	F	B	-0.8453
34	R	B	-1.4111
35	K	B	-1.8604
36	A	B	-1.9155
37	A	B	-1.7410
38	D	B	-2.6940
39	D	B	-3.0314
40	T	B	-1.9966
41	W	B	-1.4740
42	E	B	-2.1722
43	P	B	-1.1872
44	F	B	-0.7203
45	A	B	-0.5035
46	S	B	-1.0337
47	G	B	-1.6390
48	K	B	-2.6774
49	T	B	0.0000
50	S	B	-1.9462
51	E	B	-2.2365
52	S	B	-1.2038
53	G	B	0.0000
54	E	B	-1.4586
55	L	B	0.0000
56	H	B	-1.4744
57	G	B	-0.8673
58	L	B	0.0000
59	T	B	0.0000
60	T	B	-1.9558
61	E	B	-3.3022
62	E	B	-3.2524
63	E	B	-2.8335
64	F	B	0.0000
65	V	B	-1.4677
66	E	B	-2.1117
67	G	B	-1.0944
68	I	B	-0.3801
69	Y	B	0.0000
70	K	B	0.0000
71	V	B	0.0000
72	E	B	-0.7233
73	I	B	0.0000
74	D	B	-1.3366
75	T	B	0.0000
76	K	B	-1.3108
77	S	B	-1.2812
78	Y	B	0.0000
79	W	B	0.0000
80	K	B	-1.7553
81	A	B	-0.8267
82	L	B	-0.1109
83	G	B	-0.5856
84	I	B	-0.1830
85	S	B	-0.3755
86	P	B	-0.4641
87	F	B	0.0000
88	H	B	0.0000
89	E	B	-0.5837
90	H	B	-0.7314
91	A	B	0.0000
92	E	B	0.0000
93	V	B	0.0000
94	V	B	0.0000
95	F	B	0.0000
96	T	B	-0.8309
97	A	B	0.0000
98	N	B	0.0000
99	D	B	-2.3779
100	S	B	-1.5128
101	G	B	-1.5261
102	P	B	-2.2060
103	R	B	-2.2331
104	R	B	-2.2933
105	Y	B	0.0000
106	T	B	-0.0198
107	I	B	0.0000
108	A	B	0.3100
109	A	B	0.0000
110	L	B	1.0305
111	L	B	0.0000
112	S	B	0.6227
113	P	B	0.2857
114	Y	B	0.8099
115	S	B	0.5060
116	Y	B	0.0000
117	S	B	0.2595
118	T	B	0.0000
119	T	B	0.6032
120	A	B	0.0000
121	V	B	1.4032
122	V	B	0.2152
123	T	B	-0.9110
124	N	B	-1.9400