Project name: 3p0v

Chain sequence(s)	A: DIQMTQSPSSLSASVGDRVTITCRASQDLATDVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSEPEPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEVQLVESGGGLVQPGGSLRLSCAASGFTLSGDWIHWVRQAPGKGLEWLGEISAAGGYTDYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARESRVSFEAAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.3469
• Maximal score value: 2.4643
• Average score: -0.6909
• Total score value: -299.1482

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-2.3018
2	I	A	-1.8697
3	Q	A	-1.9160
4	M	A	0.0000
5	T	A	-1.2087
6	Q	A	0.0000
7	S	A	-0.7108
8	P	A	-0.5667
9	S	A	-0.8947
10	S	A	-0.4719
11	L	A	-0.2045
12	S	A	-0.6390
13	A	A	0.0000
14	S	A	-1.3159
15	V	A	-0.8528
16	G	A	-1.3305
17	D	A	-2.6738
18	R	A	-2.7358
19	V	A	-1.1575
20	T	A	-0.4020
21	I	A	0.0000
22	T	A	-0.8297
23	C	A	0.0000
24	R	A	-2.7055
25	A	A	0.0000
26	S	A	-2.1880
27	Q	A	-2.8951
28	D	A	-2.9534
29	L	A	0.0000
30	A	A	-1.3871
31	T	A	-0.8485
32	D	A	0.0000
33	V	A	0.0000
34	A	A	0.0000
35	W	A	0.0000
36	Y	A	0.0000
37	Q	A	-0.7789
38	Q	A	-1.4255
39	K	A	-1.8396
40	P	A	-1.5734
41	G	A	-1.7193
42	K	A	-2.5868
43	A	A	-1.6848
44	P	A	0.0000
45	K	A	-1.3007
46	L	A	0.0000
47	L	A	0.0000
48	I	A	0.0000
49	Y	A	1.4637
50	S	A	0.6643
51	A	A	0.0000
52	S	A	0.9566
53	F	A	2.4643
54	L	A	1.5796
55	Y	A	0.8426
56	S	A	0.1209
57	G	A	-0.4910
58	V	A	0.0000
59	P	A	-0.3508
60	S	A	-0.4514
61	R	A	-0.8521
62	F	A	0.0000
63	S	A	0.2266
64	G	A	0.0000
65	S	A	-0.4342
66	G	A	-1.5453
67	S	A	-1.5326
68	G	A	-2.0910
69	T	A	-2.6646
70	D	A	-3.0492
71	F	A	0.0000
72	T	A	-0.8276
73	L	A	0.0000
74	T	A	-0.5383
75	I	A	0.0000
76	S	A	-1.6508
77	S	A	-1.6348
78	L	A	0.0000
79	Q	A	-1.3141
80	P	A	-1.6827
81	E	A	-2.3367
82	D	A	0.0000
83	F	A	0.0000
84	A	A	0.0000
85	T	A	-0.6438
86	Y	A	0.0000
87	Y	A	0.0000
88	C	A	0.0000
89	Q	A	0.0000
90	Q	A	0.0000
91	S	A	0.0000
92	E	A	-1.7753
93	P	A	-1.7996
94	E	A	-2.3359
95	P	A	-1.8608
96	Y	A	-1.3118
97	T	A	-1.0005
98	F	A	0.0000
99	G	A	0.0000
100	Q	A	-1.6581
101	G	A	-1.2404
102	T	A	0.0000
103	K	A	-0.8862
104	V	A	0.0000
105	E	A	0.0000
106	I	A	0.0000
107	K	A	-1.4286
108	R	A	-1.2062
109	T	A	0.0656
110	V	A	1.0650
111	A	A	0.5676
112	A	A	0.2984
113	P	A	-0.1866
114	S	A	-0.2207
115	V	A	0.0000
116	F	A	0.0000
117	I	A	0.0000
118	F	A	0.0000
119	P	A	0.0000
120	P	A	0.0000
121	S	A	-1.6000
122	D	A	-2.8790
123	E	A	-2.7571
124	Q	A	0.0000
125	L	A	-2.1528
126	K	A	-2.9272
127	S	A	-1.8786
128	G	A	-1.6872
129	T	A	-1.3485
130	A	A	0.0000
131	S	A	-0.2727
132	V	A	0.0000
133	V	A	-0.1527
134	C	A	0.0000
135	L	A	0.0000
136	L	A	0.0000
137	N	A	-0.2582
138	N	A	-0.6085
139	F	A	0.0000
140	Y	A	0.0000
141	P	A	-1.2239
142	R	A	-2.1470
143	E	A	-2.8077
144	A	A	0.0000
145	K	A	-2.1581
146	V	A	-1.0221
147	Q	A	-0.5592
148	W	A	0.0000
149	K	A	-0.4522
150	V	A	0.0000
151	D	A	-1.8507
152	N	A	-1.3502
153	A	A	-0.2284
154	L	A	0.7820
155	Q	A	-0.1465
156	S	A	-0.5140
157	G	A	-1.0958
158	N	A	-1.1280
159	S	A	-1.5133
160	Q	A	-2.3028
161	E	A	-2.2560
162	S	A	-0.8393
163	V	A	-0.2860
164	T	A	0.0000
165	E	A	-1.5338
166	Q	A	0.0000
167	D	A	-1.4911
168	S	A	-1.9689
169	K	A	-2.5697
170	D	A	-2.2146
171	S	A	0.0000
172	T	A	0.0000
173	Y	A	0.0000
174	S	A	0.0000
175	L	A	-0.7239
176	S	A	-0.4992
177	S	A	0.0000
178	T	A	-0.8815
179	L	A	0.0000
180	T	A	-0.4907
181	L	A	-0.4908
182	S	A	-1.1537
183	K	A	-2.1717
184	A	A	-1.5658
185	D	A	-2.0163
186	Y	A	-2.4737
187	E	A	-3.3469
188	K	A	-3.1887
189	H	A	-3.0327
190	K	A	-3.1368
191	V	A	-1.9855
192	Y	A	0.0000
193	A	A	0.0000
194	C	A	0.0000
195	E	A	-0.7409
196	V	A	0.0000
197	T	A	-0.9789
198	H	A	0.0000
199	Q	A	-1.0592
200	G	A	0.2658
201	L	A	0.9222
202	S	A	0.1532
203	S	A	-0.0440
204	P	A	-0.3248
205	V	A	0.2890
206	T	A	-0.2262
207	K	A	-0.5816
208	S	A	-0.8572
209	F	A	0.0000
210	N	A	-2.2761
211	R	A	-2.7923
1	E	A	-2.0725
2	V	A	-1.2632
3	Q	A	-1.1756
4	L	A	0.0000
5	V	A	1.1298
6	E	A	0.2330
7	S	A	-0.4043
8	G	A	-0.9877
9	G	A	-0.4880
10	G	A	-0.2448
11	L	A	0.0140
12	V	A	-0.5531
13	Q	A	-1.5858
14	P	A	-1.8600
15	G	A	-1.5321
16	G	A	-1.3419
17	S	A	-1.7096
18	L	A	-1.5296
19	R	A	-2.4326
20	L	A	0.0000
21	S	A	-0.4728
22	C	A	0.0000
23	A	A	-0.1086
24	A	A	0.0000
25	S	A	-0.7675
26	G	A	-1.2281
27	F	A	-0.5789
28	T	A	-0.4732
29	L	A	0.0000
30	S	A	-0.5577
31	G	A	-0.4669
32	D	A	0.0000
33	W	A	-0.0157
34	I	A	0.0000
35	H	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	R	A	0.0000
39	Q	A	-0.7140
40	A	A	-1.1801
41	P	A	-1.0337
42	G	A	-1.5645
43	K	A	-2.4042
44	G	A	-1.5785
45	L	A	-0.8508
46	E	A	-0.9440
47	W	A	0.0000
48	L	A	0.0000
49	G	A	0.0000
50	E	A	0.0000
51	I	A	0.0000
52	S	A	-0.0586
53	A	A	0.0000
54	A	A	-0.4511
55	G	A	-0.5091
56	G	A	-0.3466
57	Y	A	0.3456
58	T	A	0.0807
59	D	A	-0.6263
60	Y	A	-1.0798
61	A	A	0.0000
62	D	A	-2.4494
63	S	A	-1.7052
64	V	A	0.0000
65	K	A	-2.3544
66	G	A	-1.7272
67	R	A	-1.9820
68	F	A	0.0000
69	T	A	-1.1497
70	I	A	0.0000
71	S	A	-0.3586
72	A	A	-0.7122
73	D	A	-1.4101
74	T	A	-1.2123
75	S	A	-1.4003
76	K	A	-2.1370
77	N	A	-1.3727
78	T	A	-0.7396
79	A	A	0.0000
80	Y	A	-0.5423
81	L	A	0.0000
82	Q	A	-1.9583
83	M	A	0.0000
84	N	A	-2.2747
85	S	A	-1.5533
86	L	A	0.0000
87	R	A	-2.4344
88	A	A	-1.7336
89	E	A	-2.2373
90	D	A	0.0000
91	T	A	-0.6629
92	A	A	0.0000
93	V	A	0.2477
94	Y	A	0.0000
95	Y	A	0.0000
96	C	A	0.0000
97	A	A	0.0000
98	R	A	-0.4242
99	E	A	-0.3321
100	S	A	0.0000
101	R	A	-0.7290
102	V	A	1.2337
103	S	A	1.2890
104	F	A	1.6679
105	E	A	0.0000
106	A	A	0.0000
107	A	A	0.0000
108	M	A	0.0000
109	D	A	-0.5955
110	Y	A	-0.3083
111	W	A	0.0000
112	G	A	0.0000
113	Q	A	-1.2188
114	G	A	-0.4557
115	T	A	0.0084
116	L	A	0.3570
117	V	A	0.0000
118	T	A	0.0000
119	V	A	0.0000
120	S	A	-0.7185
121	S	A	-0.6572
122	A	A	-0.4465
123	S	A	-0.5261
124	T	A	-0.5993
125	K	A	-1.0869
126	G	A	-1.3552
127	P	A	0.0000
128	S	A	-0.3264
129	V	A	0.0000
130	F	A	-0.7946
131	P	A	-0.8178
132	L	A	0.0000
133	A	A	-0.4534
134	P	A	-0.5933
135	S	A	-1.3490
136	S	A	-1.4343
137	K	A	-2.3142
138	S	A	-1.1949
139	T	A	-0.8059
140	S	A	-0.8606
141	G	A	-0.8895
142	G	A	-0.9232
143	T	A	-0.6475
144	A	A	0.0000
145	A	A	0.0000
146	L	A	0.0000
147	G	A	0.0000
148	C	A	0.0000
149	L	A	0.2042
150	V	A	0.0000
151	K	A	-0.3168
152	D	A	-0.6341
153	Y	A	0.0000
154	F	A	0.0000
155	P	A	0.0000
156	E	A	-0.4835
157	P	A	-0.5554
158	V	A	-0.4145
159	T	A	-0.6026
160	V	A	-0.3588
161	S	A	-0.3735
162	W	A	0.0000
163	N	A	-0.7236
164	S	A	-0.6182
165	G	A	-0.2884
166	A	A	-0.0998
167	L	A	0.1760
168	T	A	-0.0900
169	S	A	-0.4294
170	G	A	-0.0374
171	V	A	0.1148
172	H	A	-0.3148
173	T	A	-0.2111
174	F	A	0.0000
175	P	A	0.0088
176	A	A	0.4654
177	V	A	1.1452
178	L	A	1.5273
179	Q	A	0.3328
180	S	A	-0.1384
181	S	A	-0.2338
182	G	A	0.0453
183	L	A	0.0993
184	Y	A	0.5763
185	S	A	0.3593
186	L	A	0.0000
187	S	A	0.1271
188	S	A	0.0000
189	V	A	0.1739
190	V	A	0.0000
191	T	A	-0.0588
192	V	A	0.0000
193	P	A	-0.4928
194	S	A	-0.5652
195	S	A	-0.4995
196	S	A	0.0000
197	L	A	-0.8316
198	G	A	-1.7141
199	T	A	-1.2266
200	Q	A	-1.5129
201	T	A	-1.4791
202	Y	A	-0.8503
203	I	A	-1.1888
204	C	A	0.0000
205	N	A	-1.6053
206	V	A	0.0000
207	N	A	-1.9923
208	H	A	0.0000
209	K	A	-2.7141
210	P	A	-1.5112
211	S	A	-1.7166
212	N	A	-2.6117
213	T	A	-2.0591
214	K	A	-2.7144
215	V	A	-1.5824
216	D	A	-2.6011
217	K	A	-1.8384
218	K	A	-2.4080
219	V	A	-1.7995
220	E	A	-2.7306
221	P	A	-2.0675
222	K	A	-2.1942