Project name: 5tru:H

Chain sequence(s)	H: QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYTMHWVRQAPGKGLEWVTFISYDGNNKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAIYYCARTGWLGPFDYWGQGTLVTVSSASTKGPSVFPLAPSSKTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.7996
• Maximal score value: 2.4535
• Average score: -0.5287
• Total score value: -113.6644

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.2242
2	V	H	-0.2461
3	Q	H	-0.4682
4	L	H	0.0000
5	V	H	0.5267
6	E	H	0.0000
7	S	H	-0.5756
8	G	H	-0.8665
9	G	H	-0.3892
10	G	H	0.2040
11	V	H	0.4665
12	V	H	0.0000
13	Q	H	-1.6888
14	P	H	-1.8958
15	G	H	-1.9116
16	R	H	-2.5701
17	S	H	-2.0087
18	L	H	-1.4595
19	R	H	-2.2082
20	L	H	0.0000
21	S	H	-0.5743
22	C	H	0.0000
23	A	H	-0.2970
24	A	H	-0.4254
25	S	H	-0.5635
26	G	H	-0.8170
27	F	H	-0.3091
28	T	H	-0.1926
29	F	H	0.0000
30	S	H	-0.5386
31	S	H	0.1626
32	Y	H	0.6773
33	T	H	0.0000
34	M	H	0.0000
35	H	H	0.4332
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.3844
40	A	H	-1.0473
41	P	H	-1.0180
42	G	H	-1.4093
43	K	H	-2.0634
44	G	H	-0.8689
45	L	H	0.6413
46	E	H	-0.0956
47	W	H	0.2648
48	V	H	0.0000
49	T	H	0.0000
50	F	H	0.6247
51	I	H	0.0000
52	S	H	-0.7523
53	Y	H	-0.1101
54	D	H	-2.0746
55	G	H	-1.9343
56	N	H	-2.4251
57	N	H	-2.0486
58	K	H	-0.9050
59	Y	H	0.4629
60	Y	H	-0.2841
61	A	H	0.0000
62	D	H	-2.2557
63	S	H	-1.6183
64	V	H	0.0000
65	K	H	-2.4296
66	G	H	-1.7424
67	R	H	-1.3666
68	F	H	0.0000
69	T	H	-0.8189
70	I	H	0.0000
71	S	H	-0.9249
72	R	H	-1.0908
73	D	H	-1.7478
74	N	H	-1.8287
75	S	H	-1.6475
76	K	H	-2.4333
77	N	H	-1.9185
78	T	H	-1.1135
79	L	H	0.0000
80	Y	H	-0.5757
81	L	H	0.0000
82	Q	H	-1.5639
83	M	H	0.0000
84	N	H	-1.7195
85	S	H	-1.4785
86	L	H	0.0000
87	R	H	-2.1862
88	A	H	-1.5647
89	E	H	-2.1552
90	D	H	0.0000
91	T	H	-0.6015
92	A	H	0.0000
93	I	H	0.5346
94	Y	H	0.0000
95	Y	H	0.3699
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.0000
99	T	H	0.5923
100	G	H	0.0000
101	W	H	1.7434
102	L	H	1.7805
103	G	H	0.4758
104	P	H	0.1596
105	F	H	0.4473
106	D	H	-0.1083
107	Y	H	0.4637
108	W	H	0.4905
109	G	H	-0.0715
110	Q	H	-0.8480
111	G	H	-0.2098
112	T	H	0.0818
113	L	H	0.6462
114	V	H	0.0000
115	T	H	0.0000
116	V	H	0.0000
117	S	H	-0.7638
118	S	H	-0.6382
119	A	H	-0.4490
120	S	H	-0.5306
121	T	H	-0.5311
122	K	H	-1.1390
123	G	H	-1.3915
124	P	H	-0.5919
125	S	H	-0.1465
126	V	H	0.0000
127	F	H	1.0393
128	P	H	0.0724
129	L	H	0.4666
130	A	H	-0.8696
131	P	H	0.0000
132	S	H	-1.1512
133	S	H	-1.6218
134	K	H	-2.0359
140	T	H	-0.2400
141	A	H	-0.2183
142	A	H	0.0336
143	L	H	0.0000
144	G	H	0.0000
145	C	H	0.0000
146	L	H	0.7104
147	V	H	0.0000
148	K	H	-0.3939
149	D	H	-0.7997
150	Y	H	0.0000
151	F	H	0.0000
152	P	H	0.0000
153	E	H	-0.2460
154	P	H	-0.7615
155	V	H	-0.5000
156	T	H	-0.5648
157	V	H	-0.1880
158	S	H	-0.3004
159	W	H	0.0000
160	N	H	-0.6133
161	S	H	-0.5746
162	G	H	-0.5100
163	A	H	-0.2346
164	L	H	-0.0095
165	T	H	-0.3271
166	S	H	-0.3825
167	G	H	-0.5153
168	V	H	-0.1506
169	H	H	-0.5554
170	T	H	0.2044
171	F	H	1.1169
172	P	H	0.6444
173	A	H	1.2316
174	V	H	2.4535
175	L	H	2.0886
176	Q	H	0.5665
177	S	H	-0.1442
178	S	H	-0.2376
179	G	H	0.1768
180	L	H	0.1399
181	Y	H	0.0000
182	S	H	0.0000
183	L	H	0.0000
184	S	H	0.6878
185	S	H	0.0000
186	V	H	0.3269
187	V	H	0.0000
188	T	H	-0.2606
189	V	H	0.0000
190	P	H	-0.5969
191	S	H	-0.5166
192	S	H	-0.6301
193	S	H	-0.7569
194	L	H	-0.8840
195	G	H	-1.1121
196	T	H	-0.9014
197	Q	H	-1.3375
198	T	H	-1.2832
199	Y	H	0.0000
200	I	H	-1.4166
201	C	H	0.0000
202	N	H	-1.3709
203	V	H	0.0000
204	N	H	-1.8334
205	H	H	0.0000
206	K	H	-2.7373
207	P	H	-1.5524
208	S	H	-1.7596
209	N	H	-2.5841
210	T	H	-2.0371
211	K	H	-2.5215
212	V	H	-1.2758
213	D	H	-2.2320
214	K	H	-2.0380
215	R	H	-2.7177
216	V	H	0.0000
217	E	H	-2.7996
218	P	H	-1.9293
219	K	H	-2.4969
220	S	H	-1.2944