Project name: 1py1 modified

Chain sequence(s)	A: ETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLPEEVKIAEAYQMLKKQGIVKSDP; E: DDILLK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.4664
• Maximal score value: 1.313
• Average score: -0.9858
• Total score value: -145.9035

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
8	E	A	-2.0656
9	T	A	-1.3876
10	L	A	-1.2941
11	E	A	-1.7606
12	A	A	-1.8175
13	R	A	-1.9730
14	I	A	0.0000
15	N	A	-2.1686
16	R	A	-2.4935
17	A	A	0.0000
18	T	A	0.0000
19	N	A	-1.4576
20	P	A	-0.6885
21	L	A	0.3478
22	N	A	-1.3706
23	K	A	-2.3229
24	E	A	-2.3649
25	L	A	-1.0811
26	D	A	-1.1252
27	W	A	0.4050
28	A	A	-0.0449
29	S	A	-0.8510
30	I	A	0.0000
31	N	A	-0.9529
32	G	A	0.0000
33	F	A	0.0000
34	C	A	0.0000
35	E	A	-2.7942
36	Q	A	-2.5288
37	L	A	0.0000
38	N	A	-2.7992
39	E	A	-3.0446
40	D	A	-2.2223
41	F	A	-0.3287
42	E	A	-1.5613
43	G	A	0.0000
44	P	A	0.0000
45	P	A	-1.1626
46	L	A	-0.5660
47	A	A	0.0000
48	T	A	0.0000
49	R	A	-2.1788
50	L	A	-1.2411
51	L	A	0.0000
52	A	A	0.0000
53	H	A	-1.5885
54	K	A	-1.3783
55	I	A	0.0000
56	Q	A	-1.0361
57	S	A	-1.0675
58	P	A	-1.2367
59	Q	A	-1.4447
60	E	A	-1.5244
61	W	A	-0.7171
62	E	A	-0.8124
63	A	A	0.0000
64	I	A	0.0000
65	Q	A	0.0000
66	A	A	0.0000
67	L	A	0.0000
68	T	A	0.0000
69	V	A	0.0000
70	L	A	0.0000
71	E	A	-1.1468
72	T	A	-0.9562
73	C	A	0.0000
74	M	A	0.0000
75	K	A	-2.0707
76	S	A	-1.5495
77	C	A	-1.8818
78	G	A	-2.2734
79	K	A	-2.9855
80	R	A	-2.8667
81	F	A	0.0000
82	H	A	-2.0409
83	D	A	-2.1817
84	E	A	-1.9457
85	V	A	0.0000
86	G	A	0.0000
87	K	A	-1.2904
88	F	A	0.0000
89	R	A	-1.9841
90	F	A	0.0000
91	L	A	0.0000
92	N	A	0.0000
93	E	A	0.0000
94	L	A	0.0000
95	I	A	0.0000
96	K	A	-0.7649
97	V	A	0.0000
98	V	A	0.0000
99	S	A	0.0000
100	P	A	-1.2885
101	K	A	-1.8829
102	Y	A	-0.8044
103	L	A	-0.8060
104	G	A	0.0000
105	S	A	-1.4974
106	R	A	-2.0750
107	T	A	-2.0048
108	S	A	-2.5208
109	E	A	-3.4664
110	K	A	-3.3375
111	V	A	0.0000
112	K	A	-2.4949
113	N	A	-3.1770
114	K	A	-2.5256
115	I	A	0.0000
116	L	A	0.0000
117	E	A	-2.5550
118	L	A	0.0000
119	L	A	0.0000
120	Y	A	-0.5451
121	S	A	-0.3351
122	W	A	0.0000
123	T	A	0.3300
124	V	A	1.3130
125	G	A	-0.0367
126	L	A	-0.1943
127	P	A	-0.3440
128	E	A	-1.4127
129	E	A	-0.8765
130	V	A	0.2888
131	K	A	-0.9311
132	I	A	0.0000
133	A	A	-0.6985
134	E	A	-1.8001
135	A	A	0.0000
136	Y	A	0.0000
137	Q	A	-2.3474
138	M	A	0.0000
139	L	A	0.0000
140	K	A	-3.0017
141	K	A	-2.9397
142	Q	A	-2.1519
143	G	A	-1.8980
144	I	A	-1.3250
145	V	A	0.0000
146	K	A	-2.6670
147	S	A	-1.8822
148	D	A	-2.4115
149	P	A	-1.9269
2	D	E	-1.8488
3	D	E	-0.8988
4	I	E	0.9625
6	L	E	-0.1466
7	L	E	-0.3638
8	K	E	-1.7393