Project name: Monomer 4MXH

Chain sequence(s)	A: DFEHAISDLEAHNQAKIGVALVSENGNLIQGYRANERFAMCSTFKLPLAALVLSRIDAGEENPERKLHYDSAFLEEYYAPAAKRYVATGYMTVTEAIQQSALQLSDNAAANLLLKEVGGPPLLTKYFRSLGDKVSRLDRIEPTLNTNTPGDERDTTTPMSMAQTVSKLIFGDTLTYKSKGQLRRLLIGNQTGDKTIRAGLPDSWVTTGDKTGSCANGGRRNDVAFFITTAGKKYVLSSVYTNAPELQGEERALLIASVAKLARQYVVH
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.221
• Maximal score value: 0.9399
• Average score: -0.7884
• Total score value: -207.3571

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
21	D	A	-2.5887
22	F	A	0.0000
23	E	A	-3.2045
24	H	A	-2.8428
25	A	A	-1.9327
26	I	A	0.0000
27	S	A	-1.9311
28	D	A	-2.4715
29	L	A	-1.4097
30	E	A	0.0000
31	A	A	-1.5668
32	H	A	-1.7881
33	N	A	-2.0660
34	Q	A	-2.3829
35	A	A	-1.9138
36	K	A	-1.5185
37	I	A	0.0000
38	G	A	0.0000
39	V	A	0.0000
40	A	A	0.0000
41	L	A	0.0000
42	V	A	0.0000
43	S	A	-1.5098
44	E	A	-2.5832
45	N	A	-2.4403
46	G	A	0.0000
47	N	A	-1.3735
48	L	A	0.1701
49	I	A	0.8497
50	Q	A	-0.0748
51	G	A	-0.4687
52	Y	A	0.0000
53	R	A	-1.9907
54	A	A	-1.3712
55	N	A	-2.2458
56	E	A	-2.5450
57	R	A	-2.3910
58	F	A	0.0000
59	A	A	0.0000
60	M	A	0.0000
61	C	A	0.0000
62	S	A	-0.1685
63	T	A	0.0000
64	F	A	0.0000
65	K	A	0.0000
66	L	A	0.0000
67	P	A	0.0000
68	L	A	0.0000
69	A	A	0.0000
70	A	A	0.0000
71	L	A	0.0000
72	V	A	0.0000
73	L	A	0.0000
74	S	A	-0.7655
75	R	A	-1.5441
76	I	A	-1.3846
77	D	A	-1.4200
78	A	A	-1.2936
79	G	A	-1.8700
80	E	A	-2.5829
81	E	A	-2.4828
82	N	A	-3.0352
83	P	A	-2.2975
84	E	A	-3.2210
85	R	A	-3.1895
86	K	A	-2.8420
87	L	A	0.0000
88	H	A	-1.6801
89	Y	A	0.0000
90	D	A	-1.8206
91	S	A	-0.9524
92	A	A	-0.3498
93	F	A	-0.2535
94	L	A	-0.5305
95	E	A	-1.0311
96	E	A	-1.7877
97	Y	A	-0.4910
98	A	A	0.0000
99	P	A	-0.7827
100	A	A	-0.7814
101	A	A	0.0000
102	K	A	-1.9286
103	R	A	-1.9735
104	Y	A	-0.6501
105	V	A	-0.7587
106	A	A	-0.4568
107	T	A	-0.3172
108	G	A	-0.7513
109	Y	A	-0.8706
110	M	A	0.0000
111	T	A	-2.0231
112	V	A	0.0000
113	T	A	-1.3970
114	E	A	-1.1186
115	A	A	0.0000
116	I	A	0.0000
117	Q	A	-0.7150
118	S	A	0.0000
119	A	A	0.0000
120	L	A	0.0000
121	Q	A	-0.3711
122	L	A	-0.0276
123	S	A	-0.0285
124	D	A	0.0000
125	N	A	-0.1186
126	A	A	0.0000
127	A	A	0.0000
128	A	A	0.0000
129	N	A	0.0000
130	L	A	0.0000
131	L	A	0.0000
132	L	A	0.0000
133	K	A	-1.9116
134	E	A	-1.4847
135	V	A	0.0000
136	G	A	-1.0895
137	G	A	-0.8011
138	P	A	-0.7382
139	P	A	-0.8856
140	L	A	-0.8581
141	L	A	0.0000
142	T	A	-1.4509
143	K	A	-2.1548
144	Y	A	0.0000
145	F	A	0.0000
146	R	A	-1.8325
147	S	A	-1.1747
148	L	A	-0.9005
149	G	A	-1.1520
150	D	A	0.0000
151	K	A	-2.0583
152	V	A	-1.1496
153	S	A	0.0000
154	R	A	-1.8129
155	L	A	0.0000
156	D	A	-1.2998
157	R	A	-0.4482
158	I	A	0.5578
159	E	A	0.0000
160	P	A	-0.2997
161	T	A	-0.0677
162	L	A	0.0000
163	N	A	-0.5017
164	T	A	-0.6777
165	N	A	-1.2166
166	T	A	-1.1615
167	P	A	-1.1776
168	G	A	-1.5505
169	D	A	-2.1232
170	E	A	-3.1089
171	R	A	-2.8829
172	D	A	0.0000
173	T	A	0.0000
174	T	A	0.0000
175	T	A	0.0000
176	P	A	0.0000
177	M	A	-0.6629
178	S	A	-0.7430
179	M	A	0.0000
180	A	A	0.0000
181	Q	A	-0.9972
182	T	A	0.0000
183	V	A	0.0000
184	S	A	0.0000
185	K	A	-1.6479
186	L	A	0.0000
187	I	A	0.0000
188	F	A	-1.1070
189	G	A	-1.5720
190	D	A	-1.8049
191	T	A	-1.0279
192	L	A	0.0000
193	T	A	-0.6712
194	Y	A	-0.1148
195	K	A	-1.4353
196	S	A	0.0000
197	K	A	-1.2116
198	G	A	-1.3167
199	Q	A	-1.7685
200	L	A	0.0000
201	R	A	-1.2587
202	R	A	-1.9220
203	L	A	-1.0961
204	L	A	0.0000
205	I	A	0.2041
206	G	A	-0.7241
207	N	A	0.0000
208	Q	A	-1.4217
209	T	A	-1.3338
210	G	A	0.0000
211	D	A	-2.9448
212	K	A	-2.6736
213	T	A	0.0000
214	I	A	0.0000
215	R	A	-1.5411
216	A	A	-1.4581
217	G	A	0.0000
218	L	A	0.0000
219	P	A	-1.1621
220	D	A	-1.7831
221	S	A	-0.8326
222	W	A	0.0000
223	V	A	0.8542
224	T	A	0.2412
225	G	A	0.0000
226	D	A	0.0000
227	K	A	0.0000
228	T	A	0.0000
229	G	A	0.0000
230	S	A	-0.5991
231	C	A	-0.5776
232	A	A	-0.8012
233	N	A	-1.7456
234	G	A	-1.5183
235	G	A	0.0000
236	R	A	-0.7234
237	N	A	0.0000
238	D	A	0.0000
239	V	A	0.0000
240	A	A	0.0000
241	F	A	0.0000
242	F	A	0.0000
243	I	A	-0.2344
244	T	A	0.0000
245	T	A	-0.5699
246	A	A	-0.4605
247	G	A	-0.7277
248	K	A	-1.6212
249	K	A	-1.6373
250	Y	A	0.0000
251	V	A	0.0000
252	L	A	0.0000
253	S	A	0.0000
254	V	A	0.0000
255	Y	A	0.0000
256	T	A	0.0000
257	N	A	-1.4479
258	A	A	0.0000
259	P	A	-2.1642
260	E	A	-2.7721
261	L	A	-2.3033
262	Q	A	-2.5342
263	G	A	-2.3804
264	E	A	-2.7878
265	E	A	-2.3002
266	R	A	-1.8816
267	A	A	0.0000
268	L	A	-0.0803
269	L	A	0.0000
270	I	A	0.0000
271	A	A	-0.5836
272	S	A	-0.1322
273	V	A	0.0000
274	A	A	0.0000
275	K	A	-1.6181
276	L	A	-1.0225
277	A	A	0.0000
278	R	A	-1.3642
279	Q	A	-1.3004
280	Y	A	0.0724
281	V	A	0.0000
282	V	A	0.9399
283	H	A	-0.4782