Project name: 5xhf:B

Chain sequence(s)	B: EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTYIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGDGFYAMDYWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0907
• Maximal score value: 2.43
• Average score: -0.5643
• Total score value: -120.756

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	B	-2.0431
2	V	B	-1.0513
3	Q	B	-1.2707
4	L	B	0.0000
5	V	B	0.4235
6	E	B	0.0000
7	S	B	-0.6365
8	G	B	-1.0990
9	G	B	-0.6294
10	G	B	-0.0613
11	L	B	0.0571
12	V	B	0.0000
13	Q	B	-1.6069
14	P	B	-1.6901
15	G	B	-1.3052
16	G	B	-1.0419
17	S	B	-1.0605
18	L	B	-1.1768
19	R	B	-2.0928
20	L	B	0.0000
21	S	B	-0.5076
22	C	B	0.0000
23	A	B	-0.2934
24	A	B	0.0000
25	S	B	-1.0332
26	G	B	-1.3095
27	F	B	-1.4184
28	N	B	-2.5059
29	I	B	0.0000
30	K	B	-2.9766
31	D	B	-3.0907
32	T	B	0.0000
33	Y	B	-0.7182
34	I	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.5950
40	A	B	-1.2112
41	P	B	-1.0022
42	G	B	-1.4219
43	K	B	-2.1286
44	G	B	-1.0445
45	L	B	0.3476
46	E	B	-0.6274
47	W	B	0.0186
48	V	B	0.0000
49	A	B	0.0000
50	R	B	-0.6992
51	I	B	0.0000
52	Y	B	-0.4839
53	P	B	-1.2442
54	T	B	-1.3048
55	N	B	-1.0153
56	G	B	-0.5775
57	Y	B	0.4582
58	T	B	-0.5332
59	R	B	-2.0669
60	Y	B	-1.9015
61	A	B	-1.8946
62	D	B	-2.7077
63	S	B	-1.8100
64	V	B	0.0000
65	K	B	-2.9371
66	G	B	-1.8197
67	R	B	-1.4338
68	F	B	0.0000
69	T	B	-1.0795
70	I	B	0.0000
71	S	B	-0.1450
72	A	B	-0.9421
73	D	B	-1.5241
74	T	B	-1.9252
75	S	B	-1.6206
76	K	B	-2.2483
77	N	B	-1.8852
78	T	B	0.0000
79	A	B	0.0000
80	Y	B	-0.5218
81	L	B	0.0000
82	Q	B	-1.0917
83	M	B	0.0000
84	N	B	-1.2801
85	S	B	-1.1579
86	L	B	0.0000
87	R	B	-2.4260
88	A	B	-1.7828
89	E	B	-2.3140
90	D	B	0.0000
91	T	B	-0.7759
92	A	B	0.0000
93	V	B	0.4016
94	Y	B	0.0000
95	Y	B	0.4144
96	C	B	0.0000
97	S	B	0.0000
98	R	B	-0.3584
99	W	B	-0.0938
100	G	B	0.0000
101	G	B	-0.5290
102	D	B	-1.5516
103	G	B	0.1327
104	F	B	1.7768
105	Y	B	1.6302
106	A	B	0.7819
107	M	B	0.5298
108	D	B	-0.0118
109	Y	B	0.3381
110	W	B	0.2086
111	G	B	-0.2222
112	Q	B	-0.9511
113	G	B	-0.2439
114	T	B	-0.0483
115	L	B	0.1956
116	V	B	0.0000
117	T	B	0.0000
118	V	B	0.0000
119	S	B	-0.7756
120	S	B	-0.6703
121	A	B	-0.4427
122	S	B	-0.5217
123	T	B	-0.6872
124	K	B	-1.0786
125	G	B	-1.3739
126	P	B	0.0000
127	S	B	-0.1539
128	V	B	0.0000
129	F	B	0.6963
130	P	B	0.1395
131	L	B	0.4710
132	A	B	-0.1898
133	P	B	-0.3087
134	S	B	-0.2655
141	G	B	-0.7156
142	T	B	-0.4651
143	A	B	0.0000
144	A	B	0.0397
145	L	B	0.0000
146	G	B	0.0000
147	C	B	0.0000
148	L	B	0.6703
149	V	B	0.0000
150	K	B	-0.3098
151	D	B	-0.5657
152	Y	B	0.0000
153	F	B	0.0000
154	P	B	0.0000
155	E	B	-0.6722
156	P	B	-0.7533
157	V	B	-0.4736
158	T	B	-0.4172
159	V	B	-0.2946
160	S	B	-0.5165
161	W	B	0.0000
162	N	B	-0.7543
163	S	B	-0.6770
164	G	B	-0.5317
165	A	B	-0.2526
166	L	B	-0.0628
167	T	B	-0.3203
168	S	B	-0.3824
169	G	B	-0.4824
170	V	B	-0.0042
171	H	B	-0.4505
172	T	B	0.2538
173	F	B	1.1095
174	P	B	0.7976
175	A	B	1.2591
176	V	B	2.4300
177	L	B	1.9853
178	Q	B	0.5337
179	S	B	0.0277
180	S	B	-0.2275
181	G	B	0.1940
182	L	B	0.2492
183	Y	B	0.7492
184	S	B	0.0000
185	L	B	0.9511
186	S	B	0.7173
187	S	B	0.0000
188	V	B	0.5182
189	V	B	0.0000
190	T	B	-0.3289
191	V	B	0.0000
192	P	B	-0.5855
193	S	B	-0.6002
194	S	B	-0.6139
195	S	B	0.0000
196	L	B	-0.8831
197	G	B	-1.1073
198	T	B	-1.0247
199	Q	B	-1.5033
200	T	B	-1.2180
201	Y	B	0.0000
202	I	B	-1.3085
203	C	B	0.0000
204	N	B	-1.5737
205	V	B	0.0000
206	N	B	-2.0216
207	H	B	0.0000
208	K	B	-2.7413
209	P	B	-1.5866
210	S	B	-1.8210
211	N	B	-2.6078
212	T	B	-2.0665
213	K	B	-2.8101
214	V	B	-1.7714
215	D	B	-2.6464
216	K	B	-2.1845
217	K	B	-2.1908
218	V	B	0.0000
219	E	B	-2.3617
220	P	B	-1.0997