Project name: 5id1:B
Status: done
submitted: 2019-03-20 15:57:14, status changed: 2019-03-20 17:27:49
Settings
|
Chain sequence(s)
|
B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.9116
-
Maximal score value
-
2.4571
-
Average score
-
-0.5008
-
Total score value
-
-107.1671
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
B |
-1.5051 |
|
| 2 |
V |
B |
-0.9252 |
|
| 3 |
Q |
B |
-1.6842 |
|
| 4 |
L |
B |
0.0000 |
|
| 5 |
K |
B |
-2.1771 |
|
| 6 |
Q |
B |
0.0000 |
|
| 7 |
S |
B |
-0.8530 |
|
| 8 |
G |
B |
-1.0394 |
|
| 9 |
P |
B |
-0.3474 |
|
| 10 |
G |
B |
-0.3159 |
|
| 11 |
L |
B |
-0.0679 |
|
| 12 |
V |
B |
0.0000 |
|
| 13 |
Q |
B |
-1.5368 |
|
| 14 |
P |
B |
-1.3723 |
|
| 15 |
S |
B |
-1.5811 |
|
| 16 |
Q |
B |
-1.9304 |
|
| 17 |
S |
B |
-1.8893 |
|
| 18 |
L |
B |
0.0000 |
|
| 19 |
S |
B |
-0.9307 |
|
| 20 |
I |
B |
0.0000 |
|
| 21 |
T |
B |
-0.6117 |
|
| 22 |
C |
B |
0.0000 |
|
| 23 |
T |
B |
-1.1546 |
|
| 24 |
V |
B |
0.0000 |
|
| 25 |
S |
B |
-1.2542 |
|
| 26 |
G |
B |
-1.0068 |
|
| 27 |
F |
B |
-0.5628 |
|
| 28 |
S |
B |
-0.8825 |
|
| 29 |
L |
B |
0.0000 |
|
| 30 |
T |
B |
-0.8971 |
|
| 31 |
N |
B |
-0.8919 |
|
| 32 |
Y |
B |
0.4002 |
|
| 33 |
G |
B |
0.0000 |
|
| 34 |
V |
B |
0.0000 |
|
| 35 |
H |
B |
0.0000 |
|
| 36 |
W |
B |
0.0000 |
|
| 37 |
V |
B |
0.0000 |
|
| 38 |
R |
B |
0.0000 |
|
| 39 |
Q |
B |
-0.3229 |
|
| 40 |
S |
B |
-0.9705 |
|
| 41 |
P |
B |
-1.1352 |
|
| 42 |
G |
B |
-1.6559 |
|
| 43 |
K |
B |
-2.0574 |
|
| 44 |
G |
B |
-0.7181 |
|
| 45 |
L |
B |
0.6894 |
|
| 46 |
E |
B |
0.0670 |
|
| 47 |
W |
B |
0.4140 |
|
| 48 |
L |
B |
0.0000 |
|
| 49 |
G |
B |
0.0000 |
|
| 50 |
V |
B |
0.0000 |
|
| 51 |
I |
B |
0.0000 |
|
| 52 |
W |
B |
-0.6226 |
|
| 53 |
S |
B |
-0.6733 |
|
| 54 |
G |
B |
-1.2276 |
|
| 55 |
G |
B |
-1.5253 |
|
| 56 |
N |
B |
-1.9690 |
|
| 57 |
T |
B |
-1.5275 |
|
| 58 |
D |
B |
-1.5300 |
|
| 59 |
Y |
B |
-0.6482 |
|
| 60 |
N |
B |
-0.6140 |
|
| 61 |
T |
B |
-0.5083 |
|
| 62 |
P |
B |
-0.4607 |
|
| 63 |
F |
B |
0.0000 |
|
| 64 |
T |
B |
-0.5980 |
|
| 65 |
S |
B |
-0.6715 |
|
| 66 |
R |
B |
-1.3029 |
|
| 67 |
L |
B |
0.0000 |
|
| 68 |
S |
B |
-1.3343 |
|
| 69 |
I |
B |
0.0000 |
|
| 70 |
N |
B |
-1.7898 |
|
| 71 |
K |
B |
-1.4126 |
|
| 72 |
D |
B |
-1.7041 |
|
| 73 |
N |
B |
-2.0746 |
|
| 74 |
S |
B |
-1.6123 |
|
| 75 |
K |
B |
-2.3177 |
|
| 76 |
S |
B |
-1.5553 |
|
| 77 |
Q |
B |
-1.5156 |
|
| 78 |
V |
B |
0.0000 |
|
| 79 |
F |
B |
-0.4836 |
|
| 80 |
F |
B |
0.0000 |
|
| 81 |
K |
B |
-2.0693 |
|
| 82 |
M |
B |
0.0000 |
|
| 83 |
N |
B |
-2.3336 |
|
| 84 |
S |
B |
-1.6837 |
|
| 85 |
L |
B |
0.0000 |
|
| 86 |
Q |
B |
-2.1458 |
|
| 87 |
S |
B |
-1.5461 |
|
| 88 |
N |
B |
-2.0612 |
|
| 89 |
D |
B |
0.0000 |
|
| 90 |
T |
B |
-0.6850 |
|
| 91 |
A |
B |
0.0000 |
|
| 92 |
I |
B |
0.5433 |
|
| 93 |
Y |
B |
0.0000 |
|
| 94 |
Y |
B |
-0.0382 |
|
| 95 |
C |
B |
0.0000 |
|
| 96 |
A |
B |
0.0000 |
|
| 97 |
R |
B |
0.0000 |
|
| 98 |
A |
B |
0.0000 |
|
| 99 |
L |
B |
1.9068 |
|
| 100 |
T |
B |
1.4627 |
|
| 101 |
Y |
B |
1.9994 |
|
| 102 |
Y |
B |
1.8462 |
|
| 103 |
D |
B |
0.9654 |
|
| 104 |
Y |
B |
0.9975 |
|
| 105 |
E |
B |
0.1292 |
|
| 106 |
F |
B |
0.7187 |
|
| 107 |
A |
B |
0.8498 |
|
| 108 |
Y |
B |
0.5702 |
|
| 109 |
W |
B |
0.1118 |
|
| 110 |
G |
B |
0.0000 |
|
| 111 |
Q |
B |
-1.4252 |
|
| 112 |
G |
B |
0.0000 |
|
| 113 |
T |
B |
0.0000 |
|
| 114 |
L |
B |
0.4538 |
|
| 115 |
V |
B |
0.0000 |
|
| 116 |
T |
B |
-0.2771 |
|
| 117 |
V |
B |
0.0000 |
|
| 118 |
S |
B |
-0.5786 |
|
| 119 |
A |
B |
-0.3765 |
|
| 120 |
A |
B |
-0.2917 |
|
| 121 |
S |
B |
-0.4858 |
|
| 122 |
T |
B |
-0.6755 |
|
| 123 |
K |
B |
-1.1522 |
|
| 124 |
G |
B |
-1.3881 |
|
| 125 |
P |
B |
0.0000 |
|
| 126 |
S |
B |
-0.1681 |
|
| 127 |
V |
B |
0.0000 |
|
| 128 |
F |
B |
0.8659 |
|
| 129 |
P |
B |
-0.1041 |
|
| 130 |
L |
B |
0.3708 |
|
| 131 |
A |
B |
-0.9060 |
|
| 132 |
P |
B |
-0.7377 |
|
| 139 |
G |
B |
-0.7612 |
|
| 140 |
G |
B |
-0.8810 |
|
| 141 |
T |
B |
-0.6185 |
|
| 142 |
A |
B |
-0.3451 |
|
| 143 |
A |
B |
0.0988 |
|
| 144 |
L |
B |
0.0000 |
|
| 145 |
G |
B |
0.0000 |
|
| 146 |
C |
B |
0.0000 |
|
| 147 |
L |
B |
0.6949 |
|
| 148 |
V |
B |
0.0000 |
|
| 149 |
K |
B |
-0.2126 |
|
| 150 |
D |
B |
-0.5373 |
|
| 151 |
Y |
B |
0.0000 |
|
| 152 |
F |
B |
-0.1766 |
|
| 153 |
P |
B |
0.0000 |
|
| 154 |
E |
B |
0.0116 |
|
| 155 |
P |
B |
-0.3935 |
|
| 156 |
V |
B |
-0.5378 |
|
| 157 |
T |
B |
-0.5526 |
|
| 158 |
V |
B |
-0.3159 |
|
| 159 |
S |
B |
-0.5061 |
|
| 160 |
W |
B |
0.0000 |
|
| 161 |
N |
B |
-0.9751 |
|
| 162 |
S |
B |
-0.6890 |
|
| 163 |
G |
B |
-0.5970 |
|
| 164 |
A |
B |
-0.2627 |
|
| 165 |
L |
B |
-0.0560 |
|
| 166 |
T |
B |
-0.3176 |
|
| 167 |
S |
B |
-0.3308 |
|
| 168 |
G |
B |
-0.3710 |
|
| 169 |
V |
B |
-0.1131 |
|
| 170 |
H |
B |
-0.5902 |
|
| 171 |
T |
B |
0.0404 |
|
| 172 |
F |
B |
0.8542 |
|
| 173 |
P |
B |
0.6891 |
|
| 174 |
A |
B |
1.2574 |
|
| 175 |
V |
B |
2.4571 |
|
| 176 |
L |
B |
2.1449 |
|
| 177 |
Q |
B |
0.6556 |
|
| 178 |
S |
B |
0.0667 |
|
| 179 |
S |
B |
-0.2212 |
|
| 180 |
G |
B |
0.2374 |
|
| 181 |
L |
B |
0.3819 |
|
| 182 |
Y |
B |
0.9252 |
|
| 183 |
S |
B |
0.7647 |
|
| 184 |
L |
B |
0.0000 |
|
| 185 |
S |
B |
0.6145 |
|
| 186 |
S |
B |
0.0000 |
|
| 187 |
V |
B |
0.3498 |
|
| 188 |
V |
B |
0.0000 |
|
| 189 |
T |
B |
-0.2149 |
|
| 190 |
V |
B |
0.0000 |
|
| 191 |
P |
B |
-0.5903 |
|
| 192 |
S |
B |
-0.5784 |
|
| 193 |
S |
B |
-0.6307 |
|
| 194 |
S |
B |
-0.6665 |
|
| 195 |
L |
B |
-0.8167 |
|
| 196 |
G |
B |
-0.9802 |
|
| 197 |
T |
B |
-0.7899 |
|
| 198 |
Q |
B |
-1.3752 |
|
| 199 |
T |
B |
-1.2776 |
|
| 200 |
Y |
B |
0.0000 |
|
| 201 |
I |
B |
-1.5369 |
|
| 202 |
C |
B |
0.0000 |
|
| 203 |
N |
B |
-1.4916 |
|
| 204 |
V |
B |
0.0000 |
|
| 205 |
N |
B |
-1.8920 |
|
| 206 |
H |
B |
0.0000 |
|
| 207 |
K |
B |
-2.4886 |
|
| 208 |
P |
B |
-1.4290 |
|
| 209 |
S |
B |
-1.7003 |
|
| 210 |
N |
B |
-2.4784 |
|
| 211 |
T |
B |
-2.0196 |
|
| 212 |
K |
B |
-2.6609 |
|
| 213 |
V |
B |
-1.7146 |
|
| 214 |
D |
B |
-2.3157 |
|
| 215 |
K |
B |
-2.0125 |
|
| 216 |
R |
B |
-2.6316 |
|
| 217 |
V |
B |
0.0000 |
|
| 218 |
E |
B |
-2.9116 |
|
| 219 |
P |
B |
-1.8764 |
|
| 220 |
K |
B |
-2.2457 |
|