Project name: 4g6j:H

Chain sequence(s)	H: QVQLVESGGGVVQPGRSLRLSCAASGFTFSVYGMNWVRQAPAKGLEWVAIIWYDGDNQYYADSVKGRFTISRDNSKNTLYLQMNGLRAEDTAVYYCARDLRTGPFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVAP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0349
• Maximal score value: 2.4546
• Average score: -0.5354
• Total score value: -116.7099

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.3502
2	V	H	-0.5931
3	Q	H	-1.1045
4	L	H	0.0000
5	V	H	0.0559
6	E	H	0.0000
7	S	H	-0.5896
8	G	H	-0.8009
9	G	H	-0.4487
10	G	H	-0.0542
11	V	H	0.0692
12	V	H	0.0000
13	Q	H	-1.8989
14	P	H	-2.2173
15	G	H	-2.1907
16	R	H	-2.7875
17	S	H	-1.7783
18	L	H	-1.2876
19	R	H	-1.7319
20	L	H	0.0000
21	S	H	-0.4683
22	C	H	0.0000
23	A	H	-0.3701
24	A	H	0.0000
25	S	H	-0.6197
26	G	H	-0.7641
27	F	H	0.0302
28	T	H	0.5983
29	F	H	0.0000
30	S	H	0.3818
31	V	H	1.8391
32	Y	H	1.0797
33	G	H	0.0000
34	M	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.4688
40	A	H	-0.9869
41	P	H	-0.8451
42	A	H	-1.0552
43	K	H	-1.8342
44	G	H	-0.8569
45	L	H	0.5222
46	E	H	-0.3816
47	W	H	0.0112
48	V	H	0.0000
49	A	H	0.0000
50	I	H	0.0000
51	I	H	0.0000
52	W	H	-0.4436
53	Y	H	0.3409
54	D	H	-1.8268
55	G	H	-1.9664
56	D	H	-2.9268
57	N	H	-2.2240
58	Q	H	-0.6624
59	Y	H	0.4855
60	Y	H	-0.3906
61	A	H	-1.1388
62	D	H	-2.2599
63	S	H	-1.7909
64	V	H	0.0000
65	K	H	-2.4449
66	G	H	-1.8426
67	R	H	-1.5009
68	F	H	0.0000
69	T	H	-0.7221
70	I	H	0.0000
71	S	H	-0.7384
72	R	H	-1.1667
73	D	H	-1.6272
74	N	H	-1.5197
75	S	H	-1.5100
76	K	H	-2.2677
77	N	H	-1.5696
78	T	H	-0.9603
79	L	H	0.0000
80	Y	H	-0.4196
81	L	H	0.0000
82	Q	H	-1.0452
83	M	H	0.0000
84	N	H	-1.9209
85	G	H	-1.8748
86	L	H	0.0000
87	R	H	-3.0349
88	A	H	-1.9147
89	E	H	-2.4171
90	D	H	0.0000
91	T	H	-0.8335
92	A	H	0.0000
93	V	H	0.2048
94	Y	H	0.0000
95	Y	H	0.3101
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.0000
99	D	H	0.0000
100	L	H	-0.5676
101	R	H	-1.7239
102	T	H	-0.7767
103	G	H	-1.0001
104	P	H	-0.4700
105	F	H	0.2884
106	D	H	0.1480
107	Y	H	0.8193
108	W	H	0.5780
109	G	H	-0.1837
110	Q	H	-1.0415
111	G	H	-0.3462
112	T	H	-0.1503
113	L	H	0.0827
114	V	H	0.0000
115	T	H	0.0000
116	V	H	0.0000
117	S	H	-1.1478
118	S	H	-0.5712
119	A	H	-0.4340
120	S	H	-0.5456
121	T	H	-0.5766
122	K	H	-1.1616
123	G	H	-1.4499
124	P	H	0.0000
125	S	H	-0.1120
126	V	H	0.0000
127	F	H	0.8508
128	P	H	0.3062
129	L	H	0.8890
130	A	H	-0.1002
131	P	H	0.0000
132	S	H	-0.8223
133	S	H	-1.1853
134	K	H	-1.9087
135	S	H	-0.9843
136	T	H	-1.0155
137	S	H	-0.9212
138	G	H	-0.8606
139	G	H	-0.9207
140	T	H	-0.6641
141	A	H	0.0000
142	A	H	-0.2083
143	L	H	0.0000
144	G	H	0.0000
145	C	H	0.0000
146	L	H	0.7709
147	V	H	0.0000
148	K	H	-0.3039
149	D	H	-0.4123
150	Y	H	0.0000
151	F	H	0.0000
152	P	H	0.0000
153	E	H	-0.2150
154	P	H	-0.5722
155	V	H	-0.3818
156	T	H	-0.5485
157	V	H	-0.1594
158	S	H	-0.4198
159	W	H	0.0000
160	N	H	-0.8432
161	S	H	-0.6718
162	G	H	-0.4920
163	A	H	-0.2160
164	L	H	-0.0311
165	T	H	-0.2749
166	S	H	-0.3876
167	G	H	-0.4925
168	V	H	-0.0307
169	H	H	-0.5163
170	T	H	0.0601
171	F	H	0.8047
172	P	H	0.5959
173	A	H	1.2575
174	V	H	2.4546
175	L	H	2.1211
176	Q	H	0.5881
177	S	H	-0.1798
178	S	H	-0.2247
179	G	H	-0.0145
180	L	H	0.2345
181	Y	H	0.7924
182	S	H	0.7251
183	L	H	0.8803
184	S	H	0.6475
185	S	H	0.0000
186	V	H	0.4362
187	V	H	0.0000
188	T	H	-0.2613
189	V	H	0.0000
190	P	H	-0.5572
191	S	H	-0.5907
192	S	H	-0.5491
193	S	H	-0.5350
194	L	H	-0.3889
195	G	H	-0.7036
196	T	H	-0.7052
197	Q	H	-1.0538
198	T	H	-0.8619
199	Y	H	0.0000
200	I	H	-1.4059
201	C	H	0.0000
202	N	H	-1.6396
203	V	H	0.0000
204	N	H	-1.9489
205	H	H	0.0000
206	K	H	-2.7008
207	P	H	-1.5591
208	S	H	-1.8388
209	N	H	-2.5010
210	T	H	-2.0645
211	K	H	-2.8131
212	V	H	-1.9235
213	D	H	-2.8368
214	K	H	-2.2935
215	R	H	-2.4036
216	V	H	0.0000
217	A	H	-0.7057
218	P	H	-0.4454