Project name: 3i9g:H

Chain sequence(s)	H: EVQLVQSGAEVKKPGESLKISCQSFGYIFIDHTIHWMRQMPGQGLEWMGAISPRHDITKYNEMFRGQVTISADKSSSTAYLQWSSLKASDTAMYFCARGGFYGSTIWFDFWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0623
• Maximal score value: 2.448
• Average score: -0.5085
• Total score value: -112.877

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.8016
2	V	H	-0.5577
3	Q	H	-0.6561
4	L	H	0.0000
5	V	H	0.4745
6	Q	H	0.0000
7	S	H	-0.5091
8	G	H	-0.4704
9	A	H	-0.0550
10	E	H	-0.2755
11	V	H	0.2107
12	K	H	-1.0312
13	K	H	-1.7188
14	P	H	-1.9067
15	G	H	-1.8770
16	E	H	-2.0790
17	S	H	-1.7699
18	L	H	0.0000
19	K	H	-1.9755
20	I	H	0.0000
21	S	H	-0.4174
22	C	H	0.0000
23	Q	H	-0.0715
24	S	H	0.0000
25	F	H	0.9132
26	G	H	-0.0915
27	Y	H	0.6989
28	I	H	1.8005
29	F	H	0.0000
30	I	H	-0.9739
31	D	H	-1.2006
32	H	H	-0.6996
33	T	H	0.0000
34	I	H	0.0000
35	H	H	0.0000
36	W	H	0.0000
37	M	H	0.0000
38	R	H	-0.1221
39	Q	H	-0.4428
40	M	H	-0.5746
41	P	H	-0.8703
42	G	H	-1.2856
43	Q	H	-1.5557
44	G	H	-0.7353
45	L	H	0.6139
46	E	H	0.0635
47	W	H	0.3993
48	M	H	0.0000
49	G	H	0.0000
50	A	H	0.0000
51	I	H	0.0000
52	S	H	0.0000
52A	P	H	0.0000
53	R	H	-2.4968
54	H	H	-1.8902
55	D	H	-2.2321
56	I	H	-0.6178
57	T	H	-0.8187
58	K	H	-1.8891
59	Y	H	-1.6986
60	N	H	-1.5953
61	E	H	-2.4822
62	M	H	-0.8070
63	F	H	0.0000
64	R	H	-3.0623
65	G	H	-2.1054
66	Q	H	-2.2075
67	V	H	0.0000
68	T	H	-1.2035
69	I	H	0.0000
70	S	H	-0.5288
71	A	H	-1.1735
72	D	H	-1.8528
73	K	H	-2.5100
74	S	H	-1.3098
75	S	H	-0.8730
76	S	H	-0.4817
77	T	H	0.0000
78	A	H	0.0000
79	Y	H	-0.5031
80	L	H	0.0000
81	Q	H	-1.4427
82	W	H	0.0000
82A	S	H	-1.3322
82B	S	H	-1.6958
82C	L	H	0.0000
83	K	H	-2.3198
84	A	H	-1.2175
85	S	H	-0.8141
86	D	H	-0.8568
87	T	H	-0.3995
88	A	H	0.0000
89	M	H	0.2735
90	Y	H	0.0000
91	F	H	0.3237
92	C	H	0.0000
93	A	H	0.0000
94	R	H	0.0696
95	G	H	0.0000
96	G	H	0.5573
97	F	H	0.9152
98	Y	H	1.2491
99	G	H	0.4544
100	S	H	0.8097
100A	T	H	1.1192
100B	I	H	1.9242
100C	W	H	1.3356
100D	F	H	0.5924
101	D	H	-0.5688
102	F	H	-0.1963
103	W	H	0.1349
104	G	H	0.0000
105	Q	H	-0.8796
106	G	H	-0.3258
107	T	H	0.0000
108	M	H	0.1915
109	V	H	0.0000
110	T	H	-0.2398
111	V	H	0.0000
112	S	H	-0.7806
113	S	H	-0.8472
114	A	H	-0.4673
115	S	H	-0.5529
116	T	H	-0.6064
117	K	H	-1.2377
118	G	H	-1.5164
119	P	H	0.0000
120	S	H	-0.0492
121	V	H	0.0000
122	F	H	1.2600
123	P	H	0.2352
124	L	H	0.4294
125	A	H	-0.9906
126	P	H	0.0000
127	S	H	0.0000
128	S	H	-1.4041
129	K	H	-2.0398
130	S	H	-1.1939
131	T	H	-0.9843
132	S	H	-0.9333
133	G	H	-0.8849
134	G	H	-0.9058
135	T	H	-0.6498
136	A	H	0.0000
137	A	H	-0.1848
138	L	H	0.0000
139	G	H	0.0000
140	C	H	0.0000
141	L	H	0.7706
142	V	H	0.0000
143	K	H	-0.2593
144	D	H	-0.5868
145	Y	H	0.0000
146	F	H	0.0000
147	P	H	0.0000
148	E	H	-0.7509
149	P	H	-1.0064
150	V	H	-0.8279
151	T	H	-0.6711
152	V	H	-0.4534
153	S	H	-0.4354
154	W	H	0.0000
155	N	H	-0.8185
156	S	H	-0.6898
157	G	H	-0.5324
158	A	H	-0.2421
159	L	H	-0.0509
160	T	H	-0.3342
161	S	H	-0.3912
162	G	H	-0.5046
163	V	H	-0.1616
164	H	H	-0.6241
165	T	H	0.0086
166	F	H	0.8154
167	P	H	0.6288
168	A	H	1.1906
169	V	H	2.4480
170	L	H	2.1127
171	Q	H	0.7096
172	S	H	0.1280
173	S	H	-0.1796
174	G	H	0.3903
175	L	H	0.1624
176	Y	H	0.7182
177	S	H	0.0000
178	L	H	0.0000
179	S	H	0.6318
180	S	H	0.0000
181	V	H	0.2998
182	V	H	0.0000
183	T	H	-0.2813
184	V	H	0.0000
185	P	H	-0.6141
186	S	H	-0.6377
187	S	H	-0.6225
188	S	H	0.0000
189	L	H	-0.8895
190	G	H	-1.0542
191	T	H	-0.7577
192	Q	H	-1.2940
193	T	H	-1.2157
194	Y	H	0.0000
195	I	H	-1.5893
196	C	H	0.0000
197	N	H	-1.5749
198	V	H	0.0000
199	N	H	-2.1200
200	H	H	0.0000
201	K	H	-2.8744
202	P	H	-1.7560
203	S	H	-1.8853
204	N	H	-2.6810
205	T	H	-2.1210
206	K	H	-2.7569
207	V	H	-1.6811
208	D	H	-2.6729
209	K	H	-2.1848
210	R	H	-2.6649
211	V	H	0.0000
212	E	H	-2.8153
213	P	H	-1.7891
214	K	H	-2.3061